A Definition and Categorization System for Advanced Materials: The Foundation for Risk‐Informed Environmental Health and Safety Testing

Novel materials with unique or enhanced properties relative to conventional materials are being developed at an increasing rate. These materials are often referred to as advanced materials (AdMs) and they enable technological innovations that can benefit society. Despite their benefits, however, the unique characteristics of many AdMs, including many nanomaterials, are poorly understood and may pose environmental safety and occupational health (ESOH) risks that are not readily determined by traditional risk assessment methods. To assess these risks while keeping up with the pace of development, technology developers and risk assessors frequently employ risk‐screening methods that depend on a clear definition for the materials that are to be assessed (e.g., engineered nanomaterial) as well as a method for binning materials into categories for ESOH risk prioritization. The term advanced material lacks a consensus definition and associated categorization or grouping system for risk screening. In this study, we aim to establish a practitioner‐driven definition for AdMs and a practitioner‐validated framework for categorizing AdMs into conceptual groupings based on material characteristics. Results from multiple workshops and interviews with practitioners provide consistent differentiation between AdMs and conventional materials, offer functional nomenclature for application science, and provide utility for future ESOH risk assessment prioritization. The definition and categorization framework established here serve as a first step in determining if and when there is a need for specific ESOH and regulatory screening for an AdM as well as the type and extent of risk‐related information that should be collected or generated for AdMs and AdM‐enabled technologies.     

Competing risk analysis in a large cardiovascular clinical trial: An APEX substudy

Competing risk methods are time‐to‐event analyses that account for fatal and/or nonfatal events that may potentially alter or prevent a subject from experiencing the primary endpoint. Competing risk methods may provide a more accurate and less biased estimate of the incidence of an outcome but are rarely applied in cardiology trials. APEX investigated the efficacy of extended‐duration betrixaban versus standard‐duration enoxaparin to prevent a composite of symptomatic deep‐vein thrombosis (proximal or distal), nonfatal pulmonary embolism, or venous thromboembolism (VTE)–related death in acute medically ill patients (n = 7513). The aim of the current analysis was to determine the efficacy of betrixaban vs standard‐duration enoxaparin accounting for non‐VTE–related deaths using the Fine and Gray method for competing risks. The proportion of non‐VTE–related death was similar in both the betrixaban (133, 3.6%) and enoxaparin (136, 3.7%) arms, P = .85. Both the traditional Kaplan‐Meier method and the Fine and Gray method accounting for non‐VTE–related death as a competing risk showed equal reduction of VTE events when comparing betrixaban to enoxaparin (HR/SHR = 0.65, 95% 0.42‐0.99, P = 0.046). Due to the similar proportion of non‐VTE–related deaths in both treatment arms and the use of a univariate model, the Fine and Gray method provided identical results to the traditional Cox model. Using the Fine and Gray method in addition to the traditional Cox proportional hazards method can indicate whether the presence of a competing risk, which is dependent of the outcome, altered the risk estimate.     

The relation of economic class and fertility: An analysis of some Indonesian data

Summary Many recent fertility studies in developing societies put forward the hypothesis of a negative relation between economic class and fertility. Data showing a positive relationship are frequently dismissed a priori as resulting from the reporting errors of illiterate women. This study draws on data from Indonesia's 1971 Census, a 1973 sample survey of fertility and mortality, and an intensive community study in Java, to argue that an observed positive relation between class and fertility is real, and is related to differences in patterns of marital disruption, postpartum abstinence, and fecundity. The positive relation may be reversed in the future as changes in these patterns, and the impact of the national family planning programme, affect the family structure of each class differently. Had the positive relation in this context been attributed offhand to reporting errors, these important socio-economic changes would have been misunderstood, and possibly ignored.     

Factor structure of quality of life: The Lehman interview

This study of 67 chronically mentally ill outpatients with psychotic disorders examined subjective quality of life scores from Lehman's Quality of Life (QOL) interview. Factor analyses identified ‘Affiliative’ and ‘Instrumental’ dimensions which accounted for 67% of the variance in subjective satisfaction ratings. The results suggest a model in which instrumental and affiliative needs comprise significant portions of subjective life satisfaction and that global QOL satisfaction is related more to instrumental than affiliative needs. These findings further clarify the concept of life satisfaction in this population of severely mentally ill individuals and suggest modifications in how quality of life information is evaluated.     

MEASURING HUMAN WELLNESS

A conceptual framework is presented as a means to organize the many measures of human wellness that are now available. Health and human wellness are now often used interchangeably and there has been considerable augmentation of the indicators of progress – in addition to traditional indicators such as life expectancy and mortality rates, there is now an ability to use more positive indicators such as self-related health and self-esteem.     

Publication Rates of Undergraduate Social Work Programs in Selected Journals

Abstract

Scholarship is receiving an ever-increasing emphasis within social work education, particularly at the undergraduate level. Decisions on recruitment, reappointment, tenure, salary, and promotion often are influenced by publication productivity. The authors extend previous research on publication activity of graduate faculty by reporting the journal article production of undergraduate social work faculty over a 7-year period in seven major social work journals. As expected from earlier studies, relatively few faculty produced a sizable proportion of the articles. However, articles written by only one author were less common than previous research suggested. The majority of articles appeared in three of the journals reviewed: Social Work, Journal of Social Work Education, and Families in Society (formerly Social Casework). The most prolific undergraduate faculty were likely to come from programs located in combined bachelor of social work/master of social work settings in relatively large public universities. Gender differences were noted in only one area: twice as many women authors were among the most prolific baccalaureate contributors.