Building a Human Health Risk Assessment Ontology (RsO): A Proposed Framework

Over the last decade the health and environmental research communities have made significant progress in collecting and improving access to genomic, toxicology, exposure, health, and disease data useful to health risk assessment. One of the barriers to applying these growing volumes of information in fields such as risk assessment is the lack of informatics tools to organize, curate, and evaluate thousands of journal publications and hundreds of databases to provide new insights on relationships among exposure, hazard, and disease burden. Many fields are developing ontologies as a way of organizing and analyzing large amounts of complex information from multiple scientific disciplines. Ontologies include a vocabulary of terms and concepts with defined logical relationships to each other. Building from the recently published exposure ontology and other relevant health and environmental ontologies, this article proposes an ontology for health risk assessment (RsO) that provides a structural framework for organizing risk assessment information and methods. The RsO is anchored by eight major concepts that were either identified by exploratory curations of the risk literature or the exposure‐ontology working group as key for describing the risk assessment domain. These concepts are: (1) stressor, (2) receptor, (3) outcome, (4) exposure event, (5) dose‐response approach, (6) dose‐response metric, (7) uncertainty, and (8) measure of risk. We illustrate the utility of these concepts for the RsO with example curations of published risk assessments for ionizing radiation, arsenic in drinking water, and persistent pollutants in salmon.     

On An Intriguing Distributional Identity

For a continuous random variable X with support equal to (a, b), with c.d.f. F, and g: Ω₁ → Ω₂ a continuous, strictly increasing function, such that Ω₁∩Ω₂?(a, b), but otherwise arbitrary, we establish that the random variables F(X) ? F(g(X)) and F(g^{? 1}(X)) ? F(X) have the same distribution. Further developments, accompanied by illustrations and observations, address as well the equidistribution identity U ? ψ(U) = ^dψ^{? 1}(U) ? U for U ～ U(0, 1), where ψ is a continuous, strictly increasing and onto function, but otherwise arbitrary. Finally, we expand on applications with connections to variance reduction techniques, the discrepancy between distributions, and a risk identity in predictive density estimation.     

Deep Uncertainties in Sea-Level Rise and Storm Surge Projections: Implications for Coastal Flood Risk Management

Sea levels are rising in many areas around the world, posing risks to coastal communities and infrastructures. Strategies for managing these flood risks present decision challenges that require a combination of geophysical, economic, and infrastructure models. Previous studies have broken important new ground on the considerable tensions between the costs of upgrading infrastructure and the damages that could result from extreme flood events. However, many risk-based adaptation strategies remain silent on certain potentially important uncertainties, as well as the tradeoffs between competing objectives. Here, we implement and improve on a classic decision-analytical model (Van Dantzig 1956) to: (i) capture tradeoffs across conflicting stakeholder objectives, (ii) demonstrate the consequences of structural uncertainties in the sea-level rise and storm surge models, and (iii) identify the parametric uncertainties that most strongly influence each objective using global sensitivity analysis. We find that the flood adaptation model produces potentially myopic solutions when formulated using traditional mean-centric decision theory. Moving from a single-objective problem formulation to one with multiobjective tradeoffs dramatically expands the decision space, and highlights the need for compromise solutions to address stakeholder preferences. We find deep structural uncertainties that have large effects on the model outcome, with the storm surge parameters accounting for the greatest impacts. Global sensitivity analysis effectively identifies important parameter interactions that local methods overlook, and that could have critical implications for flood adaptation strategies.     

Feminist Christian Realism

While Christianity and feminism may seem at odds with one another, both make normative claims about justice and addressing the needs of those on the margins of power. This article explores what feminism contributes to Christian realism. The current revival of Niebuhrian Christian realism highlights how much it still has to offer as a theoretical underpinning for policy and governance. However, Christian realism remains wedded to masculinist abstractions and power structures, such as the balance of power, that are ultimately harmful to those on the margins. Thus, this article uses feminism to argue for a greater acceptance of vulnerability and obligation in Christian realism.     

Happy People Have Children: Choice and Self-Selection into Parenthood

There is mixed evidence in the existing literature on whether children are associated with greater subjective well-being, with the correlation depending on which countries and populations are considered. We here provide a systematic analysis of this question based on three different datasets: two cross-national and one national panel. We show that the association between children and subjective well-being is positive only in developed countries, and for those who become parents after the age of 30 and who have higher income. We also provide evidence of a positive selection into parenthood, whereby happier individuals are more likely to have children.     

Vacant land conversion to community gardens: influences on generalist arthropod predators and biocontrol services in urban greenspaces

Due to economic decline and the recent rise in home foreclosure, many U.S. cities are faced with managing large acreages of vacant land. Interest in local food production on this land has the potential to dramatically reshape the composition of greenspace found within urban landscapes. This study examined how the conversion of vacant land to urban gardens and farms influenced arthropod generalist predator populations and their ability to support biocontrol services. We found that the abundance of Coccinellidae and Syrphidae, and the activity density of Carabidae, Formicidae, and Lycosidae were equivalent among vacant lot and urban garden sites. Dolichopodidae abundance and the activity density of Linyphiidae and Opiliones were reduced in urban gardens whereas Anthocoridae abundance and the activity density of Staphylinidae were greater within urban gardens relative to vacant lots. The biocontrol service supplied by generalist predators was measured using sentinel eggs (Helicoverpa zea (Noctuiidae)) and pupae (Sarcophaga bullata (Sarcophagidae) and Musca domestica (Muscidae)). We found no difference in the biocontrol of H. zea eggs or M. domestica pupae among the focal greenspaces. We found no difference in the removal of S. bullata pupae by predators in June 2010, whereas in August 2010 a greater proportion of pupae were removed in urban garden sites relative to vacant lots. Based on these findings, we discuss the potential of the urban landscape to support generalist predators and sustainable urban gardening and farming.     

What Cruising Infants Understand about Support for Locomotion

“Cruising” infants can only walk using external support to augment their balance. We examined cruisers' understanding of support for upright locomotion under four conditions: cruising over a wooden handrail at chest height, a large gap in the handrail, a wobbly unstable handrail, and an ill‐positioned low handrail. Infants distinguished among the support properties of the handrails with differential attempts to cruise and handrail‐specific forms of haptic exploration and gait modifications. They consistently attempted the wood handrail, rarely attempted the gap, and occasionally attempted the low and wobbly handrails. On the wood and gap handrails, attempt rates matched the probability of cruising successfully, but on the low and wobbly handrails, attempt rates under‐ and overestimated the probability of success, respectively. Haptic exploration was most frequent and varied on the wobbly handrail, and gait modifications—including previously undocumented “knee cruising”—were most frequent and effective on the low handrail. Results are discussed in terms of developmental changes in the meaning of support.     

Sociological Research on Feminism and the Women’s Movement: Ideology,Identity, and Practice

This article provides an overview of sociological research on three aspects of feminism: feminism as an ideology; feminism as an identity; and feminism as a practice. I summarize the main contributions of sociological research in each of these areas, and highlight the overarching contributions for understanding contemporary feminism. Three contributions are key. First, sociological research highlights the existence multiple varieties of feminism –“feminisms” as opposed to a singular “feminism.” Second, this research reveals that feminist ideologies, identities, and movements are each dynamic – they have changed historically, and continue to change in response to shifting socio‐political, economic, and technological landscapes. Third, sociological research demonstrates that feminism is alive and well, and in many senses thriving, in the contemporary United States. Though some aspects of feminism are more widespread than others, sociological research challenges the notion that feminism, on the whole, has declined. As an ideology, an identity, and a practice, feminism remains strong in the contemporary United States.