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961.
Statistical Methods & Applications - We examine general decision problems with loss functions that are bounded below. We allow the loss function to assume the value $$\infty $$ . No other...  相似文献   
962.
Population Research and Policy Review - Social surveys prospectively linked with death records provide invaluable opportunities for the study of the relationship between social and economic...  相似文献   
963.
Disabled people in Ghana continue to experience various forms of discrimination and social exclusion. These occur despite the fact that there are several anti-discriminatory laws that are meant to protect the rights of disabled people and facilitate their participation in mainstream social, political and economic activities. As it is, the laws have not completely eroded the discrimination and in some instances appear to even institutionalise the discrimination that disabled people experience. It is important that the state pays more attention to amending aspects of these laws and putting them into practice.  相似文献   
964.
Dose–response modeling of biological agents has traditionally focused on describing laboratory‐derived experimental data. Limited consideration has been given to understanding those factors that are controlled in a laboratory, but are likely to occur in real‐world scenarios. In this study, a probabilistic framework is developed that extends Brookmeyer's competing‐risks dose–response model to allow for variation in factors such as dose‐dispersion, dose‐deposition, and other within‐host parameters. With data sets drawn from dose–response experiments of inhalational anthrax, plague, and tularemia, we illustrate how for certain cases, there is the potential for overestimation of infection numbers arising from models that consider only the experimental data in isolation.  相似文献   
965.
Journal of Risk and Uncertainty - Economists have long employed hedonic wage analysis to estimate income-fatality risk trade-offs, but some scholars have raised concerns about systematic...  相似文献   
966.
The Bayesian information criterion (BIC) is widely used for variable selection. We focus on the regression setting for which variations of the BIC have been proposed. A version that includes the Fisher Information matrix of the predictor variables performed best in one published study. In this article, we extend the evaluation, introduce a performance measure involving how closely posterior probabilities are approximated, and conclude that the version that includes the Fisher Information often favors regression models having more predictors, depending on the scale and correlation structure of the predictor matrix. In the image analysis application that we describe, we therefore prefer the standard BIC approximation because of its relative simplicity and competitive performance at approximating the true posterior probabilities.  相似文献   
967.
In group sequential clinical trials, there are several sample size re-estimation methods proposed in the literature that allow for change of sample size at the interim analysis. Most of these methods are based on either the conditional error function or the interim effect size. Our simulation studies compared the operating characteristics of three commonly used sample size re-estimation methods, Chen et al. (2004), Cui et al. (1999), and Muller and Schafer (2001). Gao et al. (2008) extended the CDL method and provided an analytical expression of lower and upper threshold of conditional power where the type I error is preserved. Recently, Mehta and Pocock (2010) extensively discussed that the real benefit of the adaptive approach is to invest the sample size resources in stages and increasing the sample size only if the interim results are in the so called “promising zone” which they define in their article. We incorporated this concept in our simulations while comparing the three methods. To test the robustness of these methods, we explored the impact of incorrect variance assumption on the operating characteristics. We found that the operating characteristics of the three methods are very comparable. In addition, the concept of promising zone, as suggested by MP, gives the desired power and smaller average sample size, and thus increases the efficiency of the trial design.  相似文献   
968.
Abstract

By modeling double exponential smoothing as a weighted directed acyclic graph, we design an implementation of rolling window double exponential smoothing which is incremental-decremental in the sense that points can be added to and removed from the window with overhead and computation independent of the window size. This has applications to real-time streaming analytics systems having certain universality and flexibility requirements.  相似文献   
969.
This article provides the analytical characterization of the inverse of the information matrix for second-order SPD. A particular feature of these explicit expressions is that they are functions of the design parameters enabling the development of analytical functions to efficiently compute exact design optimality criteria. The application of these analytical expressions is demonstrated using the generalized variance of the parameter estimates for second-order SPD. An example illustrating the use of these expressions is also presented.  相似文献   
970.
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