Through observations from real life hub networks, we introduce the multimodal hub location and hub network design problem. We approach the hub location problem from a network design perspective. In addition to the location and allocation decisions, we also study the decision on how the hub networks with different possible transportation modes must be designed. In this multimodal hub location and hub network design problem, we jointly consider transportation costs and travel times, which are studied separately in most hub location problems presented in the literature. We allow different transportation modes between hubs and different types of service time promises between origin–destination pairs while designing the hub network in the multimodal problem. We first propose a linear mixed integer programming model for this problem and then derive variants of the problem that might arise in certain applications. The models are enhanced via a set of effective valid inequalities and an efficient heuristic is developed. Computational analyses are presented on the various instances from the Turkish network and CAB data set. 相似文献
This article presents a quasi-experimental study of a mindfulness-based intervention for traumatically bereaved individuals using a single group with pre-test and post-test design. The intervention consists of the ATTEND model, which is comprised of the following elements practiced by the clinician: attunement, trust, therapeutic touch, egalitarianism, nuance, and death education. The study is based on the charts of 42 clients seeking grief counseling at a mental health agency viewed retrospectively. Participants’ intake scores on the Impact of Event Scale-Revised (IES-R), which measures trauma symptoms, and 25-item Hopkins Symptom Checklist (HSCL-25), which measures depressive and anxious symptoms, were compared to their scores after an average of 14.64 hours of counseling. Paired samples t tests showed a statistically significant decline in trauma symptoms on the IES-R, and in anxious and depressive symptoms on the HSCL-25. These results provide preliminary support for the use of this mindfulness-based approach for difficulties associated with traumatic bereavement, though more extensive research is needed to determine the effectiveness of this approach. 相似文献
This study addresses how journalists respond to public relations (PR) practitioners in co-creating value for their audiences. The co-creation perspective is conceptualized by synthesizing extant literature from public relations and relationship marketing, including cultivation strategies in organization-public relationships studies, two-way symmetrical model in excellence theory, intereffication model, service-dominant (S-D) logic of co-creation in marketing, and customer engagement theories. Using long-interview technique with 18 journalists, the study investigates how journalists perceive media relations activities of PR practitioners from a value co-creation dimension. A new theoretical model titled press engagement behavior (PEB) with sub-dimensions in press participation behavior (PPB) and press citizenship behavior (PCB) is proposed. A thirty-item scale is proposed to guide future study on scale development and validation. The proposed new model can explain the context of journalist engagement, enriching the operational value of cultivation strategies in dyadic relationship settings. 相似文献
Little is known about social work practice via public libraries. Faced with patron needs, libraries seek creative ways to provide social services. One suburban library carried out community engagement using a community-university partnership. Students reviewed literature, surveyed 32 library patrons, and conducted interviews with five staff members. Patrons identified need for services related to children’s success in school as well as resources needed for health care, food resources, and employment services. They also identified concerns with homelessness, mental illness, and unemployment. Implications support the provision of social work practice at this library to address opportunities to maximize quality of life. 相似文献
Introduction: The aim of this study is to evaluate prostate-specific antigen decline pattern including prostate-specific antigen kinetics following androgen deprivation therapy on prostate-specific antigen progression in the patients with advanced prostate cancer.
Materials and methods: Ninety-seven advanced prostate cancer patients receiving maximum androgen deprivation therapy were enrolled in case–control study. Baseline prostate-specific antigen, Gleason Score, bone metastase, nadir prostate-specific antigen, time to nadir prostate-specific antigen, declining slope to nadir prostate-specific antigen, estimated baseline prostate-specific antigen half-time, current prostate-specific antigen, post-nadir prostate-specific antigen time, estimated prostate-specific antigen, estimated decline of baseline prostate-specific antigen as quantitative, and ratio were recorded and calculated.
Results: The ratio of prostate-specific antigen progression was significantly lower at the patients who had slower declining slope to prostate-specific antigen, longer time to nadir prostate-specific antigen, and lower estimated decline ratio of baseline prostate-specific antigen (p: .016, p: .020, and p: .026, respectively).
Conclusions: The shorter time to nadir prostate-specific antigen following androgen deprivation therapy, faster declining slope to nadir prostate-specific antigen and higher estimated decline ratio of baseline prostate-specific antigen are associated with higher risk of disease progression in patients with hormone-sensitive prostate cancer. 相似文献
Cross-national health research devotes considerable attention to lifespan and survival rate disparities that are found between countries. However, the distribution of mortality across the world is shaped mostly by what happens within countries. We address this striking gap in the literature by modeling length-of-life inequality for individual nation-states. We use life tables from the United Nation’s (2015) World Population Prospects to estimate inequality levels for 200 countries across 13 waves between 1950 and 2015. We find that lifespan inequality is steadily declining across the world, but that each country’s level of inequality, and the rate at which it declines, vary considerably. Our models account for more than 90% of the longitudinal and cross-sectional variation in country-level lifespan inequality during the 1990–2015 period. Maternal mortality is the strongest predictor in our model, while disease prevalence, access to safe water, and health interventions figure prominently, as well. Gross domestic product per capita shows the expected curvilinear association with lifespan inequality, while primary education (both overall enrollment and gender equity in enrollment), external debt, and migration also play critical roles in shaping health outcomes. By contrast, the distribution of political and economic resources (i.e., democracy and income inequality) is less important.
This paper argues that a group of white residents on the Lower East Side of Manhattan use a New York City English (NYCE) feature – non‐rhoticity in the syllable coda – in the construction of a place identity, one aspect of identity tied to localness and authenticity. A quantitative analysis confirms that the change in progress towards rhoticity in NYCE ( Labov 1966 ) continues to advance slowly, so that non‐rhoticity remains a resource for New Yorkers, imbued with local social meaning. Ethnographic observation of the Lower East Side reveals conflict among residents, which motivates one group to highlight their place identity by using non‐rhoticity. These Lower East Siders utilize micro‐variation of /r/ in stretches of interview talk, increasing non‐rhoticity when discussing neighborhood topics. Results support a social practice approach to stylistic and sociolinguistic variation, where Lower East Siders use /r/ in constructing a place identity in order to present themselves as authentic neighborhood residents. 相似文献