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131.
Time series data are increasingly common in many areas of the health sciences, and in some instances, may have natural boundaries serving as performance guidelines or as thresholds associated with adverse outcomes. Such boundaries may be labeled as semi-reflective, in that the time series values have an increased chance of returning towards middle levels as the boundaries are approached, but boundaries can still be breached. In this paper we review a model that was previously proposed for such data and we investigate its statistical properties. Specifically, this model consists of a third-order auto-regressive projection component, parameterized as a constrained linear combination of linear, flat, and quadratic trends, and an error term that uses a logistic regression model for its sign. We describe and compare a previously-proposed estimation method with a modified version thereof, using computer simulations, as well as data examples from heart monitoring and from a driving simulator. We find that the two methods tend to give different results, with the modified technique having lower bias and more accurate confidence intervals than the previously-proposed method. 相似文献
132.
Babak Shahbaba Shiwei Lan Wesley O. Johnson Radford M. Neal 《Statistics and Computing》2014,24(3):339-349
We show how the Hamiltonian Monte Carlo algorithm can sometimes be speeded up by “splitting” the Hamiltonian in a way that allows much of the movement around the state space to be done at low computational cost. One context where this is possible is when the log density of the distribution of interest (the potential energy function) can be written as the log of a Gaussian density, which is a quadratic function, plus a slowly-varying function. Hamiltonian dynamics for quadratic energy functions can be analytically solved. With the splitting technique, only the slowly-varying part of the energy needs to be handled numerically, and this can be done with a larger stepsize (and hence fewer steps) than would be necessary with a direct simulation of the dynamics. Another context where splitting helps is when the most important terms of the potential energy function and its gradient can be evaluated quickly, with only a slowly-varying part requiring costly computations. With splitting, the quick portion can be handled with a small stepsize, while the costly portion uses a larger stepsize. We show that both of these splitting approaches can reduce the computational cost of sampling from the posterior distribution for a logistic regression model, using either a Gaussian approximation centered on the posterior mode, or a Hamiltonian split into a term that depends on only a small number of critical cases, and another term that involves the larger number of cases whose influence on the posterior distribution is small. 相似文献
133.
Partial least squares regression (PLS) is one method to estimate parameters in a linear model when predictor variables are nearly collinear. One way to characterize PLS is in terms of the scaling (shrinkage or expansion) along each eigenvector of the predictor correlation matrix. This characterization is useful in providing a link between PLS and other shrinkage estimators, such as principal components regression (PCR) and ridge regression (RR), thus facilitating a direct comparison of PLS with these methods. This paper gives a detailed analysis of the shrinkage structure of PLS, and several new results are presented regarding the nature and extent of shrinkage. 相似文献
134.
In the paper we present a new method of calculating sampling intervals, so-called windows, allowing an experimenter some flexibility in timing the sample collection, while a minimum required design efficiency for parameter estimation is assured. The method is based on the Equivalence Theorem for D-optimality what makes the length of each window related to the parameter sensitivities. An example of calculating the windows in a pharmacokinetic study is presented. Some other methods of calculating efficient sampling windows are briefly discussed. 相似文献
135.
136.
We are trapped in two divergent worlds when it comes to global views on homosexuality. There is the liberal world epitomized by Spain and other nations, where homosexuality is increasingly accepted; gays and lesbians are claiming their human rights; and laws are changing to codify that transformation. The second is the extremely anti-gay world symbolized by Africa, the Middle East and parts of Asia, where attitudes are favorable to criminalization. This research explains the “African Gap” in attitudes toward homosexuality in a comparative analysis of six African nations and Argentina and Canada, South and North America's most liberal nations on gay rights. Using Pew's 2015 Spring Global Attitudes Survey data, we find that the major variables have essentially similar effects on opinion in any context. Africa's distinction is explained by its comparatively higher levels of factors such as religion, morality dogma, and low socioeconomic status that generally retard support for homosexuality, at the same time of lower levels of factors such as education, urbanization, and personal liberty that increase gay support. Africa's extreme anti-gay outlook is mutable. Two social forces will facilitate this softening: expansion of liberalizing agents such as education and urbanization, and repositioning away from “traditionalism” toward modernism emphasizing individualism, civil rights, and personal liberties. 相似文献
137.
The authors describe the curricular changes made as part of a 20-year commitment by Smith College School for Social Work (SCSSW), a graduate school with a clinical social work specialization, to become an antiracism institution. Unaware of precedents, faculty, administration, and students needed to develop structures and processes to confront inherent institutional racism at the SCSSW. In addition to multiple administrative actions, every aspect of the curriculum was reevaluated, leading to changes in courses offered and everything about them, from syllabi to pedagogy, as well as how faculty are trained and supported. The authors found that explicit and implicit curriculum must work together in intentional and synchronous ways. Critical intention across design, implementation, evaluation, accountability, and openness to process is emphasized here. They conclude that an antiracism commitment requires continuous engagement, connection, challenge, learning, and teaching and a curriculum that is fluid, flexible, proactive, and responsive. 相似文献
138.
ABSTRACT Homeless populations often suffer from mental illness, substance abuse, and criminality. Interventions, such as supportive housing, can have positive impacts, although benefits can be limited. This study examined outcomes for clients (N = 102) of a new supportive housing intervention. Use of formal treatment, jail contact, and community stability were compared pre- and post-housing. Jail bookings and residential substance abuse treatment significantly declined post-housing, while clients improved in income level, access to food, and housing stability. Results from official justice and treatment system data suggest that supportive housing can lead to significant changes. Future research is necessary to understand the relationship between client characteristics and outcomes. 相似文献
139.
Caroline K. Pemberton Roben Anneliese J. Bass Ginger A. Moore Laura Murray‐Kolb Patricia Z. Tan Rick O. Gilmore Kristin A. Buss Pamela M. Cole Laureen O. Teti 《Infancy》2012,17(5):558-577
Infants’ emerging ability to move independently by crawling is associated with changes in multiple domains, including an increase in expressions of anger in situations that block infants’ goals, but it is unknown whether increased anger is specifically because of experience with being able to move autonomously or simply related to age. To examine the influence of locomotion on developmental change in anger, infants’ (N = 20) anger expressions during an arm restraint procedure were observed longitudinally at a precrawling baseline assessment and 2 and 6 weeks after the onset of crawling. Infant age at each crawling stage was unrelated to the frequency of anger expressed in response to arm restraint. At 6 weeks postcrawling onset, infants whose mothers rated them as temperamentally higher in distress to limitations, compared with those rated lower, showed a greater increase in the frequency of anger expressed during the arm restraint relative to earlier assessments and took longer to reduce the frequency of anger expressed when no longer restrained. Findings suggest that experience with autonomous crawling has an effect on anger expression, independent of age, and that a temperamental tendency to become distressed by limitations may exacerbate the effect of crawling on anger expression. 相似文献
140.
Leanne ten Brinke Stephen Porter Natasha Korva Katherine Fowler Scott O. Lilienfeld Christopher J. Patrick 《Journal of Nonverbal Behavior》2017,41(3):269-287
Psychopathic individuals are characterized as “intra-species predators”—callous, impulsive, aggressive, and proficient at interpersonal manipulation. For example, despite their high risk for re-offending, psychopathic offenders often receive early release on parole. While reputed to be social chameleons, research suggests that even naive observers can accurately infer high levels of psychopathic traits in others with very brief exposures to behavior, but accuracy degrades with extended observation. We utilized a lens model approach to examine the communication styles (emotional facial expressions, body language, and verbal content) of offenders varying in levels of psychopathic traits using “thin slice” video clips of psychological assessment interviews and to reveal which cues observers use to inform their evaluations of psychopathy. Psychopathic traits were associated with more (a) Duchenne smiles, (b) negative (angry) emotional language, and (c) hand gestures (illustrators). Further, psychopathy was associated with a marked behavioral incongruence; when individuals scoring high in psychopathic traits engaged in Duchenne smiles they were also more likely to use angry language. Naïve observers relied on each of these valid behavioral signals to quickly and accurately detect psychopathic traits. These findings provide insight into psychopathic communication styles, opportunities for improving the detection of psychopathic personality traits, and may provide an avenue for understanding successful psychopathic manipulation. 相似文献