Partitioning with Respect to a Control: Unequal Sample Sizes Case

This article describes a method for partitioning with respect to a control for the situation in which the treatment sample sizes are unequal and also for the situation where the treatment sample sizes are equal except for a few missing values. Calculation of the critical values required for finding confidence limits is discussed and tables are presented for the “almost equal” sample size case. An application of this method to length of stay data for congestive heart failure patients is also provided.     

Bivariate distributions of some ratios of independent noncentral chi-square random variables

The bivariate distributions of three pairs of ratios of in¬dependent noncentral chi-square random variables are considered. These ratios arise in the problem of computing the joint power function of simultaneous F-tests in balanced ANOVA and ANCOVA. The distributions obtained are generalizations to the noncentral case of existing results in the literature. Of particular note is the bivariate noncentral F distribution, which generalizes a special case of Krishnaiah*s (1964,1965) bivariate central F distribution. Explicit formulae for the cdf's of these distribu¬tions are given, along with computational procedures     

Tables of the exact quantiles of the top-down correlation coefficient for n - 3(1)14

Iman and Connver (1985, 1987) have suggested the top-down correlation coefficient as a measure of association when n objects are ranked by two or more independent sources and interest centers primarily on agreement in the top rankings, with disagreements on items at the bottom of the rankings being of little or no importance. The top-down correlation coefficient results from computing the ordinary Pearson correlation coefficient on Savage scores. Quantiles of the exact distribution of the top-down correlation coefficient based on the assumption of independent rankings are provided for n = 3(1)14.     

Inferences from Cross-Sectional,Stochastic Frontier Models

Conventional approaches for inference about efficiency in parametric stochastic frontier (PSF) models are based on percentiles of the estimated distribution of the one-sided error term, conditional on the composite error. When used as prediction intervals, coverage is poor when the signal-to-noise ratio is low, but improves slowly as sample size increases. We show that prediction intervals estimated by bagging yield much better coverages than the conventional approach, even with low signal-to-noise ratios. We also present a bootstrap method that gives confidence interval estimates for (conditional) expectations of efficiency, and which have good coverage properties that improve with sample size. In addition, researchers who estimate PSF models typically reject models, samples, or both when residuals have skewness in the “wrong” direction, i.e., in a direction that would seem to indicate absence of inefficiency. We show that correctly specified models can generate samples with “wrongly” skewed residuals, even when the variance of the inefficiency process is nonzero. Both our bagging and bootstrap methods provide useful information about inefficiency and model parameters irrespective of whether residuals have skewness in the desired direction.     

Computational and statistical efficiency of semiparametric gls estimators

In this note, we report a dramatic improvement in the computational efficiency of semiparametric generalized least squares(SGLS) estimation. Computation of SGLS estimates no longer presents serious problems with data sets of moderate size. We also correct a numerical error in the standard errors of the SGLS estimates reported in our recent paper in this journal (Horowitz and Neumann, 1987). The corrected standard errors of SGLS are comparable to those we reported for quantile estimates.     

Three-stage designs for monitoring clinical trials

Optimal three-stage designs with equal sample sizes at each stage are presented and compared to fixed sample designs, fully sequential designs, designs restricted to use the fixed sample critical value at the final stage, and to modifications of other group sequential designs previously proposed in the literature. Typically, the greatest savings realized with interim analyses are obtained by the first interim look. More than 50% of the savings possible with a fully sequential design can be realized with a simple two-stage design. Three-stage designs can realize as much as 75% of the possible savings. Without much loss in efficiency, the designs can be modified so that the critical value at the final stage equals the usual fixed sample value while maintaining the overall level of significance, alleviating some potential confusion should a final stage be necessary. Some common group sequential designs, modified to allow early acceptance of the null hypothesis, are shown to be nearly optimal in some settings while performing poorly in others. An example is given to illustrate the use of several three-stage plans in the design of clinical trials.     

On L 1-consistency of kernel-type density estimator for stationary markov processes

A convergence result for kernel type density estimators, proved by Devroye and Gyrofi (1985), is extended to stationary Markov processess satisfying (G ₂-condition introduced by Rosenblatt (1970).     

Inflated modified power series distributions with applications

In certain applications involving discrete data, it is sometimes found that X = 0 is observed with a frequency significantly higher than predicted by the assumed model. Zero inflated Poisson, binomial and negative binomial models have been employed in some clinical trials and in some regression analysis problems.

In this paper, we study the zero inflated modified power series distributions (IMPSD) which include among others the generalized Poisson and the generalized negative binomial distributions and hence the Poisson, binomial and negative binomial distributions. The structural properties along with the distribution of the sum of independent IMPSD variables are studied. The maximum likelihood estimation of the parameters of the model is examined and the variance-covariance matrix of the estimators is obtained. Finally, examples are presented for the generalized Poisson distribution to illustrate the results.