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141.
The Norwegian Fertility Survey of 1977 shows that most of the population make adequate use of contraception. Only 7 per cent of those who did not desire to become pregnant dit not use birth control. The reduction in fertility and changes in the age-specific fertility pattern have not been as great as one would expect. The younger cohorts have not had changes in fertility as great as the changes in contraception would imply, whereas the older ones have had even greater changes. We conclude that changes in the age-specific fertility pattern have not been causally dependent on the contraceptive pattern  相似文献   
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A mechanistic model and associated procedures are proposed for cancer risk assessment of genotoxic chemicals. As previously shown for ionizing radiation, a linear multiplicative model was found to be compatible with published experimental data for ethylene oxide, acrylamide, and butadiene. The validity of this model was anticipated in view of the multiplicative interaction of mutation with inherited and acquired growth-promoting conditions. Concurrent analysis led to rejection of an additive model (i.e. the model commonly applied for cancer risk assessment). A reanalysis of data for radiogenic cancer in mouse, dog and man shows that the relative risk coefficient is approximately the same (0.4 to 0.5 percent per rad) for tumours induced in the three species.Doses in vivo, defined as the time-integrated concentrations of ultimate mutagens, expressed in millimol × kg–1 × h (mMh) are, like radiation doses given in Gy or rad, proportional to frequencies of potentially mutagenic events. The radiation dose equivalents of chemical doses are, calculated by multiplying chemical doses (in mMh) with the relative genotoxic potencies (in rad × mMh–1) determined in vitro. In this way the relative cancer incidence increments in rats and mice exposed to ethylene oxide were shown to be about 0.4 percent per rad-equivalent, in agreement with the data for radiogenic cancer.Our analyses suggest that values of the relative risk coefficients for genotoxic chemicals are independent of species and that relative cancer risks determined in animal tests apply also to humans. If reliable animal test data are not available, cancer risks may be estimated by the relative potency. In both cases exposure dose/target dose relationships, the latter via macromolecule adducts, should be determined.  相似文献   
145.
This study replicated and extended Wright (2006) and Whitehurst, Ironsmith, and Goldfein (1974) by examining whether preschool aged children would increase their use of passive grammatical voice rather than using the more age-appropriate active grammatical construction when the former was modeled by an adult. Results showed that 5 of the 6 participants began using the passive voice after this verbal behavior had been modeled. For 3 of the participants, this change was large. The change occurred even though the adult model explicitly rewarded the participant with praise and stickers for using the active voice, while providing no praise or stickers for using the passive form that was modeled. For 1 participant, the modeling procedure had no effect on use of the passive voice. These results indicate a strong automatic reinforcement effect of achieving parity with the grammatical structures used by adults, compared to the effects of explicit reinforcement by the adult. This might help to explain why children acquire grammatical structures prevalent in their language community apparently without explicit instruction.  相似文献   
146.
When evaluating human-machine interaction it is central to consider anthropometric diversity to ensure intended accommodation levels. A well-known method is the use of boundary cases where manikins with extreme but likely measurement combinations are derived by mathematical treatment of anthropometric data. The supposition by that method is that the use of these manikins will facilitate accommodation of the expected part of the total, less extreme, population. In literature sources there are differences in how many and in what way these manikins should be defined. A similar field to the boundary case method is the use of experimental design in where relationships between affecting factors of a process is studied by a systematic approach. This paper examines the possibilities to adopt methodology used in experimental design to define a group of manikins. Different experimental designs were adopted to be used together with a confidence region and its axes. The result from the study shows that it is possible to adapt the methodology of experimental design when creating groups of manikins. The size of these groups of manikins depends heavily on the number of key measurements but also on the type of chosen experimental design.  相似文献   
147.
This article proposes an interactionist update of “street‐level bureaucracy,” one of the most influential approaches for studying how public policy is translated into street‐level practice. While the street‐level approach assumes that bureaucrats are alone in enacting policy, the present article argues for seeing “street‐level policy” as formed in negotiation between bureaucrats and clients. To demonstrate this, the article uses ethnographic data and a Straussian framework to analyze how nurses and patients negotiated access in a Norwegian emergency service. The article thus sets a new course for street‐level research, helping researchers look beyond the individual to explore inter‐individual negotiation and its influence on street‐level decision‐making.  相似文献   
148.
The purpose of this study is to increase knowledge about social workers’ opportunities to work with safer sex among at-risk adolescents and young adults. To investigate this issue, a survey has been sent to outreach work and non-institutional offices whose work focuses on alcohol and drugs to some extent. The survey was sent to 89 workplaces distributed throughout 33 municipalities in the region of Skåne in southern Sweden. Altogether 229 responses were collected, a response rate of 60.1%. The study shows that social workers have limited opportunities to work with safer sex issues and that the organizational resources to support this work are weak. Michael Lipsky’s theory of street-level bureaucrats was applied to the data, with the analysis indicating that knowledge and organizational resources are key to enabling work with safer sex. It is also important that the personnel are interested in the subject and that they feel comfortable working with safer sex. The factors found to have the strongest direct effect on the personnel’s work with safer sex are: having the possibility to set aside time to work with safer sex, experiencing that safer sex is discussed at the workplace and being personally interested in the subject.  相似文献   
149.
The overarching objective of this article is to describe the Swedish public's knowledge about HIV and attitudes toward people living with HIV during the period 1987–2011. Within the framework of this objective, the article also directs a special focus at the association between knowledge about HIV transmission and attitudes toward people who are HIV positive. The study is based on the results of a questionnaire sent to a stratified random sample on eight occasions between 1987 and 2011. The study population comprises the Swedish general public aged 16–44 and is stratified on the basis of the respondents' age, with each of five age groups (16–17, 18–19, 20–24, 25–34, and 35–44) comprising 20% of the study respondents. A total of 21,027 individuals have completed the questionnaire in the eight surveys. The survey instrument is relatively short and comprises 27 questions on knowledge, attitudes and sexual behaviour relating to HIV. The eight surveys show that the public's knowledge about HIV and its different transmission routes is high and has increased over time. Above all there has been an increase in the level of knowledge about how HIV is not transmitted between people. However, the public's knowledge about the infectiousness of individuals receiving treatment for HIV infection is low. Public attitudes toward people with HIV have also undergone a clear shift over time, toward increased tolerance and a decline in the level of fear, especially in social situations. Despite this, a residual suspicion and stigmatisation can be seen in the public's attitudes to people who are HIV positive. This is most obvious from the questions that link HIV to sexuality and here the changes are very modest over time. Public knowledge about HIV and its transmission routes has increased between 1987 and 2011. Attitudes toward people who are HIV positive have generally become more tolerant and positive, not least in relation to different social situations. The fear of becoming infected has declined. At the same time there remains a stigma, which continues to direct suspicion at people who are living with HIV and to ascribe them negative characteristics and behaviors that are based on prejudice. The results show, however, that the public's attitudes toward same-sex relationships are clearly more accepting today than they were previously, and that the symbolic association between HIV and this group is tending to become weaker.  相似文献   
150.
This prospective population-based study examined associations between children’s behaviour problems and maternal employment. Information on children’s behaviour problems at 3 years from 22,115 mothers employed before pregnancy and participating in the Norwegian Mother and Child Cohort Study were linked to national register data on employment and relevant social background factors, mothers’ self-reported susceptibility to anxiety/depression and mother-reports of day-care attendance and fathers’ income. Mothers reporting their child to have severe (>2 SD) internalizing or severe combined behaviour problems (5 %) had excess risk of leaving paid employment irrespective of other important characteristics generally associated with maternal employment (RR 1.24–1.31). The attributable risk percent ranged from 30.3 % (internalizing problems) to 32.4 % (combined problems). Externalizing behaviour problems were not uniquely associated with mothers leaving employment.  相似文献   
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