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991.
Previous studies, mostly from Anglo-Saxon countries, find a positive correlation between the presence of young children in the household and self-employment probabilities among women. This has been seen as an indication of women with young children choosing self-employment as a way of balancing work and family commitments. This paper studies the relationship between children and female self-employment in a country with family friendly policies and a generous welfare system: Sweden. The initial hypothesis is that we will not find evidence of a positive effect of children on self-employment among Swedish women since there are other institutions in place aiming at facilitating the combination of work and family. Using Swedish register data for the period 2004–2008 we do, however, find that the presence of young children increases the probability of choosing self-employment also among Swedish women. The effect is strongest for women with very young children, 0–3 years of age. These results also hold in a panel data model that takes individual unobserved heterogeneity into account. We also analyze time-use data and find, contrary to what has been found in many other countries, that self-employed women spend more, or as much, time on market work than wage-earning women. This raises doubts about whether women in Sweden chose self-employment as a way of balancing work and family commitments.  相似文献   
992.
This article of the magazine Gruppe, Interaktion, Organisation (GIO) covers the role of talent management regarding the digitisation of enterprises. Talent Management contributes to this process by identifying, developing and placing talent for the digitisation of enterprises. Deutsche Bahn utilizes a variety of approaches to digitize talent management.  相似文献   
993.
Much research shows that breastfeeding provides short- and long-term health benefits for both mothers and their children. However, few studies have yet investigated the factors which may promote or inhibit breastfeeding practices in Japan. To fill this research gap, this paper uses data newly gathered in 2012 on breastfeeding initiation and duration for each child of each mother, which enable us to estimate mother fixed-effects models that control for unobserved differences among mothers. Compared to mothers who leave their jobs after childbirth, mothers who return to work within a year after childbirth do not significantly differ in breastfeeding initiation but have a breastfeeding duration which is shorter by 1.654 months. On the other hand, when fathers work under a flextime system after childbirth, breastfeeding initiation is higher, and the duration is longer by 4.418 months. Therefore, letting fathers work under a flextime system would help promote breastfeeding practices in Japan.  相似文献   
994.
995.

Background

Centenarians are a growing population in Europe and present significant variability in motor and cognitive functions. The aim of our study was to characterize health status, as well as cognitive and motor functions in a group of Portuguese centenarians. In addition, our study also aimed at analyzing the relationship between cognitive functions and the burden of diseases affecting the elderly.

Methods

Fifty-two centenarians were evaluated using the Mini-Mental State Examination, short version. Walking-related parameters (velocity and time spent in the 3 m walk test), grip strength and number of age-related illnesses were also measured. The relationship between cognitive scores and time spent in the three metre walk test, velocity, grip strength and number of diseases was analysed.

Results

Cognitive scores showed a positive correlation with both handgrip strength and time spent in the three metre walk. In contrast, no association was found between cognitive scores and the presence/absence of disease, walking velocity or number of diseases present.

Conclusions

These results suggest that in centenarians, cognitive functions may be related with motor functions.
  相似文献   
996.

Background

A low urine pH is a characteristic metabolic feature of metabolic syndrome and type 2 diabetes. The purpose of the current study was to investigate the effects of a 12-week home-based bench step exercise on the urine pH status of elderly female subjects.

Methods

The current study is a secondary analysis of a randomized controlled trial (RCT) in which 59 postmenopausal female subjects were randomized to either the exercise group (n?=?29) or the control group (n?=?30). The subjects in the exercise group were instructed to perform home-based exercises using a bench step at the anaerobic threshold (AT), with a goal of performing ≥140 min/week at home for 12 weeks. The subjects in the control group were instructed to not change their normal lifestyle. Urine was collected after overnight fasting, and the urine pH was measured using a urinary test strip. The inter-group-differences at baseline and the pre-post changes within groups were assessed using the Mann-Whitney U test and Wilcoxon’s signed-rank test, respectively. Additionally, the difference in the post-intervention urine pH levels of the two groups, adjusted for the pre-intervention values (the estimated effect size) and the precision (95% confidence intervals) were investigated using an analysis of covariance.

Results

The pre-post comparison of the urine pH data using Wilcoxon’s signed-rank test showed a significant increase in the urine pH levels of the exercise group (p?<?0.05); there was no significant change in the urine pH levels of the control group. However, the estimated effect size (0.15) was small and the confidence interval straddled 0 (?0.25–0.55).

Conclusions

Based on the results of the current secondary analysis of an RCT, we could not clearly conclude that exercise has a beneficial effect on the urine pH. Further well-designed RCTs should be conducted to determine whether aerobic exercise is truly able to ameliorate urine acidification.

Trial registration

The study was retrospectively registered in the University Hospital Medical Information Network (UMIN) as “Effect of step exercise on aerobic fitness and progression of atherosclerosis in the elderly” under the registration number UMIN 000026743 (the date of registration: March 28, 2017).
  相似文献   
997.
Youth’s perceptions of peer norms have profound effects on their attitudes and behaviors. Unfortunately, their perceptions of peers tend to be biased. To investigate the role of media in the formation of misperceived peer norms, the current study tested and compared two media-effect mechanisms: the direct exemplar mechanism and the indirect influence of presumed influence (IPI) mechanism. The two mechanisms were tested in a sample (n = 1746) that is representative of college students in one large university in China, based on which the actual and perceived campus smoking rates were examined. The individual-level perceived peer smoking prevalence was then analyzed in comparison with the campus-level actual smoking prevalence. The results revealed serious overestimations of peer smoking prevalence. As predicted, pro-smoking media content significantly heightened smoking prevalence estimates through both exemplar and IPI mechanisms. In contrast, anti-smoking messages did not elicit any intended effect through the IPI mechanism, but showed a boomerang effect through the exemplar mechanism. These findings suggest that both pro- and anti-smoking media content may be responsible for inflated perceptions of peer smoking among youth.  相似文献   
998.
High-content automated imaging platforms allow the multiplexing of several targets simultaneously to generate multi-parametric single-cell data sets over extended periods of time. Typically, standard simple measures such as mean value of all cells at every time point are calculated to summarize the temporal process, resulting in loss of time dynamics of the single cells. Multiple experiments are performed but observation time points are not necessarily identical, leading to difficulties when integrating summary measures from different experiments. We used functional data analysis to analyze continuous curve data, where the temporal process of a response variable for each single cell can be described using a smooth curve. This allows analyses to be performed on continuous functions, rather than on original discrete data points. Functional regression models were applied to determine common temporal characteristics of a set of single cell curves and random effects were employed in the models to explain variation between experiments. The aim of the multiplexing approach is to simultaneously analyze the effect of a large number of compounds in comparison to control to discriminate between their mode of action. Functional principal component analysis based on T-statistic curves for pairwise comparison to control was used to study time-dependent compound effects.  相似文献   
999.
Generalised linear models are frequently used in modeling the relationship of the response variable from the general exponential family with a set of predictor variables, where a linear combination of predictors is linked to the mean of the response variable. We propose a penalised spline (P-spline) estimation for generalised partially linear single-index models, which extend the generalised linear models to include nonlinear effect for some predictors. The proposed models can allow flexible dependence on some predictors while overcome the “curse of dimensionality”. We investigate the P-spline profile likelihood estimation using the readily available R package mgcv, leading to straightforward computation. Simulation studies are considered under various link functions. In addition, we examine different choices of smoothing parameters. Simulation results and real data applications show effectiveness of the proposed approach. Finally, some large sample properties are established.  相似文献   
1000.
In 1952, von Neumann introduced the rejection method for random variate generation. We revisit this algorithm when we have a source of perfect bits at our disposal. In this random bit model, there are universal lower bounds for generating a random variate with a given density to within an accuracy \(\epsilon \) derived by Knuth and Yao, and refined by the authors. In general, von Neumann’s method fails in this model. We propose a modification that insures proper behavior for all Riemann-integrable densities on compact sets, and show that the expected number of random bits needed behaves optimally with respect to universal lower bounds. In particular, we introduce the notion of an oracle that evaluates the supremum and infimum of a function on any rectangle of \({\mathbb {R}}^{d}\), and develop a quadtree-style extension of the classical rejection method.  相似文献   
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