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991.
Over ninety years ago Lev Vygotsky warned of a growing crisis in psychology and social science research. Vygotsky’s warning has been echoed on many occasions but his solution to the problem has not been widely acknowledged. He advocated for a form of meta-science which he called “general science”, an integrative science that could connect and guide the development of specialised disciplines and schools of research. In this paper I explore the parallels between Vygotsky’s general science and contemporary forms of meta-level research and discuss their relevance and implications for addressing global challenges.  相似文献   
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993.
The present study addresses the distinction between contemporary and old-fashioned prejudice using survey data from a national sample (n = 600) of self-identified whites living in the United States and interviewed by telephone in 2001. First, we examine associations among indicators of contemporary and old-fashioned prejudice. Consistent with the literature, contemporary and old-fashioned prejudice indicators represent two distinct but correlated common factors. Second, we examine whether belief in genetic race differences uniformly predicts both types of prejudice. As might be expected, belief in genetic race differences predicts old-fashioned prejudice but contrary to recent theorizing, it also predicts contemporary prejudice.  相似文献   
994.
We consider the use of smoothing splines for the adaptive modelling of dose–response relationships. A smoothing spline is a nonparametric estimator of a function that is a compromise between the fit to the data and the degree of smoothness and thus provides a flexible way of modelling dose–response data. In conjunction with decision rules for which doses to continue with after an interim analysis, it can be used to give an adaptive way of modelling the relationship between dose and response. We fit smoothing splines using the generalized cross‐validation criterion for deciding on the degree of smoothness and we use estimated bootstrap percentiles of the predicted values for each dose to decide upon which doses to continue with after an interim analysis. We compare this approach with a corresponding adaptive analysis of variance approach based upon new simulations of the scenarios previously used by the PhRMA Working Group on Adaptive Dose‐Ranging Studies. The results obtained for the adaptive modelling of dose–response data using smoothing splines are mostly comparable with those previously obtained by the PhRMA Working Group for the Bayesian Normal Dynamic Linear model (GADA) procedure. These methods may be useful for carrying out adaptations, detecting dose–response relationships and identifying clinically relevant doses. Copyright © 2009 John Wiley & Sons, Ltd.  相似文献   
995.
As the social context in which gay men live changes due to greater visibility, greater acceptance, and easier access to gay subculture, gay males may self-identify and take part in gay social activities at earlier ages than in the past. This study examined whether developmental milestones associated with sexual orientation for gay men have changed over the past several decades. A large and diverse sample of 2,402 gay men who responded to a 1994 survey published in a national magazine provided retrospective information on the age at which they reached individual psychological, social, and sexual behavior developmental milestones. We found evidence that individual psychological and sexual behavior milestones (e.g., awareness of attraction to males, having an orgasm with other male) are slowly moving toward earlier chronological ages (by 1 year of age every 8-25 years, p < 0.05), whereas social milestones (e.g., coming out) are moving more rapidly in a similar direction (by 1 year of age every 2-5 years, p < 0.001). The authors perform an innovative sensitivity test to demonstrate the persistence of the finding after correcting for the bias attributable to underrepresentation of those who have not yet self-identified as gay in such samples.  相似文献   
996.
Since the mid-1980s, New Zealand has experienced extensive economic, social and political reforms. The economic impact of these changes has been closely monitored and much commented upon. However, the social impacts of the reforms on different family types are less well understood. This paper outlines a project designed to monitor how the reforms impacted upon specific family types via the use of indicators of family wellbeing constructed from census data. These indicators show that for a range of family types, the reforms of the 1980s and 1990s varied in their impact, with single-parent families faring worst.
Gerard CotterellEmail:
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997.
Two studies examined the role of various fault attributions and other factors in children's anticipated response to hypothetical peers described as having an undesirable characteristic. The children were found to distinguish among various fault attributions (i.e., general, onset, and perpetuation; study 1), and they tended to agree more strongly that the peers were responsible for the perpetuation than the onset of these characteristics (studies 1 and 2). In study 1, perceiving an aggressive or overweight peer as similar to a friend and believing that the overweight peer will overcome this undesirable characteristic were found to be associated with a relatively favorable response to these peers. The more strongly the children agreed that (1) an aggressive peer is generally at fault for his/her undesirable characteristic (study 1) and (2) peers who are aggressive, overweight, shy, or a poor student are at fault for the onset of their undesirable characteristics (study 2), the less favorably they anticipated responding to these peers. Unexpectedly, attributing responsibility to forces ‘outside the peer's control’ (i.e., parents and biology) for his/her undesirable characteristic in study 2 was not found to be associated with a relatively favorable response to any peer with an undesirable characteristic.  相似文献   
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999.
1000.
Our objective was to evaluate the effect that complexity in the form of different levels of spatial, population, and contact heterogeneity has in the predictions of a mechanistic epidemic model. A model that simulates the spatiotemporal spread of infectious diseases between animal populations was developed. Sixteen scenarios of foot‐and‐mouth disease infection in cattle were analyzed, involving combinations of the following factors: multiple production‐types (PT) with heterogeneous contact and population structure versus single PT, random versus actual spatial distribution of population units, high versus low infectivity, and no vaccination versus preemptive vaccination. The epidemic size and duration was larger for scenarios with multiple PT versus single PT. Ignoring the actual unit locations did not affect the epidemic size in scenarios with multiple PT/high infectivity, but resulted in smaller epidemic sizes in scenarios using multiple PT/low infectivity. In conclusion, when modeling fast‐spreading epidemics, knowing the actual locations of population units may not be as relevant as collecting information on population and contact heterogeneity. In contrast, both population and spatial heterogeneity might be important to model slower spreading epidemic diseases. Our findings can be used to inform data collection and modeling efforts to inform health policy and planning.  相似文献   
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