Regression Models and Risk Estimation for Mixed Discrete and Continuous Outcomes in Developmental Toxicology

Multivariate dose-response models have recently been proposed for developmental toxicity data to simultaneously model malformation incidence (a binary outcome), and reductions in fetal weight (a continuous outcome). In this and other applications, the binary outcome often represents a dichotomization of another outcome or a composite of outcomes, which facilitates analysis. For example, in Segment II developmental toxicology studies, multiple malformation types (i.e., external, visceral, skeletal) are evaluated on each fetus; malformation status may also be ordinally measured (e.g., normal, signs of variation, full malformation). A model is proposed is for fetal weight and multiple malformation variables measured on an ordinal scale, where the correlations between the outcomes and between the offspring within a litter are taken into account. Fully specifying the joint distribution of outcomes within a litter is avoided by specifying only the distribution of the multivariate outcome for each fetus and using generalized estimating equation methodology to account for correlations due to litter clustering. The correlations between the outcomes are required to characterize joint risk to the fetus, and are therefore a focus of inference. Dose-response models and their application to quantitative risk assessment are illustrated using data from a recent developmental toxicology experiment of ethylene oxide in mice.     

Stress and job satisfaction in mammography radiographers

Previous research suggests that substantial numbers of health professionals experience undue levels of occupational stress. Little is yet known, however, about a recently established specialized group, namely radiographers who work in the UK National Health Service Breast Screening Programme. All 134 radiographers in the first wave of the programme were sent a postal questionnaire to determine how stressed they felt at work, how satisfied they were with the job, and what were the principal causes of stress and dissatisfaction. A total of 103 were returned, a response rate of 77 %. The results showed that 30 % reported high levels of stress, which is more than in most other professions, and that only 17% described themselves as 'very satisfied' with their jobs. The most important predictors of stress were problems of communication (mainly knowing what to tell the client) and conflicts between home and work. The most important predictor of dissatisfaction was role ambiguity. Ways of reducing stress and increasing satisfaction must be found if radiographers are to remain healthy and are to continue to work for the programme.     

Body Dysmorphic Disorder and Its Significance to Social Work

Body dysmorphic disorder (BDD) is a relatively common and often severe psychiatric disorder in which an individual has an excessive preoccupation with an imagined or slight defect in his or her appearance (American Psychiatric Association in Diagnostic and statistical manual of mental disorders. American Psychiatric Association, Washington, 2000). Despite its prevalence in the United States and worldwide, many health care and mental health professionals, including social workers, are unfamiliar with BDD. In fact, BDD is virtually absent from the social work literature and no authors or researchers have considered BDD from a social work perspective. The purpose of this article is to inform social workers about the seriousness, prevalence and treatment challenges of BDD, and to highlight its significance to social work practice and research. A clinical case presentation illustrates an example of how BDD may present in practice and the value of addressing it from a biopsychosocial perspective.     

Divergence in Age Patterns of Mortality Change Drives International Divergence in Lifespan Inequality

In the past six decades, lifespan inequality has varied greatly within and among countries even while life expectancy has continued to increase. How and why does mortality change generate this diversity? We derive a precise link between changes in age-specific mortality and lifespan inequality, measured as the variance of age at death. Key to this relationship is a young–old threshold age, below and above which mortality decline respectively decreases and increases lifespan inequality. First, we show for Sweden that shifts in the threshold’s location have modified the correlation between changes in life expectancy and lifespan inequality over the last two centuries. Second, we analyze the post–World War II (WWII) trajectories of lifespan inequality in a set of developed countries—Japan, Canada, and the United States—where thresholds centered on retirement age. Our method reveals how divergence in the age pattern of mortality change drives international divergence in lifespan inequality. Most strikingly, early in the 1980s, mortality increases in young U.S. males led to a continuation of high lifespan inequality in the United States; in Canada, however, the decline of inequality continued. In general, our wider international comparisons show that mortality change varied most at young working ages after WWII, particularly for males. We conclude that if mortality continues to stagnate at young ages yet declines steadily at old ages, increases in lifespan inequality will become a common feature of future demographic change.     

Coming out and coming back: Rural gay migration and the city

This research focuses on the complex meaning and role of the city in American and French rural gay men’s imaginary and life experience. It explores how gay men who grew up in the country build their sense of self through back-and-forth movement from rural to urban spaces. Therefore, it questions traditional gay migration studies, which have often equated gay migration and rural–urban migration, positing a unidirectional pattern. After contextualizing rural male homosexuality, this paper presents four life itineraries which highlight the central role the city has for rural gay men when exploring their same-sex desires and attractions. Based on the analysis of their life narratives, we show that for most of them, their coming out, their first same-sex experience, and coming to terms with their sexuality happens “far from home” in a city or a college town. However, this research suggests that the city has a more ambivalent role for rural gay men. While the city exists as a space of social practices where alternative sexualities can be experienced and explored, at the same time for many rural gay men the city remains substantially unattractive. In their view, the perceived “effeminizing power” of the city questions and challenges their attraction for this space. Therefore, the experience of the city becomes both liberating and disciplinary – liberating because it allows the exploration of their same-sex desires and attractions, disciplinary because it (re)presents a gay identity in which they find no resonance. Thus this research indicates that rural gay migration to the urban spaces, which is key to identity formation, includes not only departure to the city but also a necessary return to the country to maintain rural gay men’s understanding of themselves.     

Implicit theories of leadership: Stability and change over two decades

Much has changed in the last 20 years, but have people's naïve conceptions of leaders changed as well? Paralleling Offermann et al.'s (1994) study of the content of implicit leadership theories with new samples, the present study investigates ILT stability and change across a 20-year period. Results indicate that, as in 1994, Sensitivity, Dedication, Tyranny, Charisma, Strength, Masculinity, and Intelligence were confirmed as ILT factors. Analyses revealed a new factor, Creativity, and the rearranging of some characteristics across factors. The nine-factor, 46-item scale was confirmed with an independent sample, yielding superior fit indices to the eight-factor solution. This supports the view of ILTs as having both remarkably stable elements despite organizational and societal changes as well as contextually-sensitive elements. Open-ended characteristics had no references to females despite reference to males, as in 1994; thus, “think leader, think male” appears to persist in terms of naïve conceptions of leadership.     

A parent gesture intervention as a means to increase parent declarative pointing and child vocabulary

This study examined whether a brief parent gesture training resulted in a change in the communicative intent of pointing gestures used by parents of infants from age 10–12 months and whether specific types of points (declarative vs. imperative) were more or less likely to predict later child language skill at 18 months. Compared to parents who were randomized to the control group, parents in the intervention group produced significantly more declarative pointing gestures as a result of the intervention. Moreover, parents’ use of declarative points at 12 months was predictive of later child vocabulary comprehension at 18 months. These findings suggest that a short-term parent training can have important effects on the communicative intentions conveyed through gesture which predict vocabulary development.     

Choose who’s in your circle: how women’s relationship actions during and following residential treatment help create recovery-oriented networks

ABSTRACT

Women in recovery from substance use disorders often have difficulty establishing recovery-supportive networks. This exploratory study uses qualitative thematic analysis to examine how 88 women in recovery describe the actions they take to manage their personal social networks 12 months after intake into residential substance use treatment. Participants describe disconnecting or limiting contact with recovery-endangering people and adding recovery-supportive people to their networks as primary relationship actions for maintaining recovery. Their actions to build recovery-supportive networks can provide a focus for clinical work to help them become integrated into their communities.     

The impact of the Victorian infringements system on disadvantaged groups: findings from a qualitative study

This article focuses on the infringements system currently operating in the state of Victoria, Australia and, in particular, its impact on disadvantaged groups, such as people suffering homelessness, drug and alcohol dependency, mental illness, acquired brain injury, poverty, and domestic violence. The concerns of lawyers working in community legal centres striving to address the needs of people in these disadvantaged groups prompted this qualitative study, which involved in‐depth interviews with key stakeholders in the infringements system. Participants included those who issue and enforce fines, those who represent vulnerable fine recipients, and the fine recipients themselves. The research sought participants' understanding of the system, its aims, and its outcomes. This article presents an overview of the research findings in relation to the complex Victorian infringements system process, net‐widening, proportionality, and the 'special circumstances' process. Our findings suggest that the Victorian infringements system is expedient and efficient when people can promptly pay their fines. However, multiple issues need to be addressed if the system is to be just and fair to people suffering various types of disadvantage. A number of systemic changes and educational initiatives are recommended, along with law reform that addresses the unreasonable and unacceptable impacts on disadvantaged groups in Victoria.