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81.
82.
Abstract

“Physical Dependence on Nicotine in Gum: A Placebo Substitution Trial,” JOHN R. HUGHES, et al. To test whether ex-smokers become physically dependent on nicotine in gum, we entered eight ex-smokers who were using nicotine gum into a randomized, double-blind, placebo-substitution trial. When placebo was substituted, seven of the eight subjects were observed to have withdrawal symptoms and two relapsed to smoking or nicotine gum. This result suggests that physical dependence (i.e., withdrawal) may be a cause of behavioral dependence on nicotine gum (i.e., use of gum beyond the recommended period) and physicians should emphasize the need for gradual reduction of nicotine gum. (Journal of the American Medical Association 1986;255:3277–3279.)

“Absence of Therapeutic Benefit From Antacids or Cimetidine in Non-Ulcer Dyspepsia,” OLOF NYREN, et al. We randomly assigned 159 patients with non-ulcer dyspepsia, defined as chronic or recurrent epigastric pain without concomitant symptoms of the irritable bowel syndrome and with no evidence of organic disease, to treatment for three weeks with an antacid suspension one and three hours after meals, 400 mg of cimetidine twice a day, or placebo, according to a double-blind, double-dummy model. The intensity and duration of epigastric pain were recorded by the patients four times daily during a one-week period without therapy and during the three weeks of treatment. The mean reduction in pain intensity after three weeks in the placebo group was 25 percent. Neither antacid nor cimetidine treatment resulted in more than a 4 percent better effect. The reduction of pain was statistically significant (P < 0.01) in all three groups. The time course of the pain scores in the groups receiving active drugs followed closely those in the placebo group, and there were no significant differences between the groups at any stage of the treatment. We conclude that the neutralization or suppression of gastric acid is of no clinical value in patients with this syndrome. (New England Journal of Medicine 1986;314:339–43.)  相似文献   
83.
Abstract

Numerous studies of the relationship between urban population density and distance from the city's center have shown that: (1) Cross-sectionally, the relationship between density and distance is negative, such that density crests in the interior of the city and declines toward the periphery. (2) Longitudinally, the slope of the density-distance relationship becomes flatter as central densities decline as neighborhoods age and thin and as fringe areas develop and increase in population. Most studies have worked with the total relationship between density and distance, ignoring cross-sectional and longitudinal variants from the general pattern for subareas of the metropolis. Large cities seldom develop uniformily in concentric patterns focused upon the CBD. More typical is the axial pattern described by Hurd or the sectoral pattern by Hoyt in which development is axial along principal arteries of transportation with inner-axial areas developing at later points in time. This paper pursues intra-urban differences in growth and development as expressed in the density-distance relationship. Our focus is on between-sector differences in the density-distance relationship at given points in time and upon temporal differences in the relationship through time for individual sectors. Our aim is to specify in a more detailed fashion the link between general urban dynamics and the changing density-distance relationship. The data are for the Cleveland metropolitan area, 1930–1970.  相似文献   
84.
Abstract. Objective: “Drunkorexia,” limiting food intake before alcohol consumption, increases college students’ risk for negative alcohol-related health consequences. The current study tested whether (1) women engage in drunkorexia more frequently than men; (2) weight control motivations explain sex differences in drunkorexia; and (3) among women, weight control motivations are a particularly strong predictor of drunkorexia for heavier drinkers. Participants: Undergraduate males and females (N = 63) recruited during fall of 2011. Methods: Participants self-reported their alcohol consumption, drunkorexia, and weight control motivations online. Results: Findings supported hypotheses: weight control motivations explained why women engage in drunkorexia more than men; and the weight control motivation → drunkorexia relation was strongest for heavier- (vs lighter-) drinking women. Conclusion: Women have more weight concerns than men, which makes them more likely to engage in drunkorexia. Heavy-drinking women with strong weight control motivations are at greatest risk for drunkorexia. Interventions should help students more safely reconcile pressures to be thin and drink alcohol.  相似文献   
85.
This article reviews Nordic research, published from 1995 and onwards, on the relationship between unemployment and mental health among young adults. Cross‐sectional, longitudinal and time‐series studies are included. Cross‐sectional studies show that the unemployed experience more mental health problems than the non‐unemployed. Leaving unemployment is associated with increased well‐being. Economic problems, feelings of shame and poor social support increase the likelihood of psychological distress. The longitudinal studies show that unemployment increases the risk of psychological distress and attempted suicide, after initial mental health status and confounding factors are accounted for. The relationship remains significant when time‐invariant characteristics of the individuals are controlled for. The time‐series studies found no relationship between unemployment and suicide, but levels of psychological distress were found to vary with changes in the labour market. This relationship remained significant after excluding the non‐employed, indicating that unemployment trends have effects beyond those directly associated with unemployment.  相似文献   
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88.
This paper proposes a comparison of the results of tax policy analysis obtained on the basis of unitary and collective representations of the household. We first generate labour supplies consistent with the collective rationality, by use of a model calibrated on microdata as described in Vermeulen et al. [Collective Models of Household Labor Supply with Nonconvex Budget Sets and Nonparticipation: A Calibration Approach (2006)]. A unitary model is then estimated on these collective data and unitary and collective responses to a tax reform are compared. We focus on the introduction of linear taxation in Germany. The exercise is replicated for other European countries and other topical reforms. Distortions due to the use of a unitary model turn out to be important in predicting labour supply adjustments, in the design of tax revenue neutral reforms, and in predicting a reform’s welfare implications.
Denis BeningerEmail:
  相似文献   
89.
Multicultural Meanings of Social Support among Immigrants and Refugees   总被引:1,自引:1,他引:0  
Canada continues to be a prominent immigrant and refugee‐receiving country in worldwide migration, resettlement, and search for refuge, yet there is a gap in our understanding of these newcomers’ views of the specific meanings of social support and their support needs and resources. The purpose of this study was to understand the meanings of social support for immigrants and refugees in Canada, and to explore the types and adequacy of formal supports. Individual interviews were conducted with 60 service providers and policymakers initially (Phase 1), and 120 immigrants and refugees (60 Chinese, 60 Somali) in the second phase. The implications of these findings were elicited in group interviews (Phase 3) of policy decision‐makers, advocates, service providers, and managers. This investigation revealed many interrelated challenges facing refugees and immigrants such as language difficulties, inadequate information on services, poor health, racism, needs for retraining, rejection of foreign qualifications, unemployment, social isolation, social insecurity, dwindling social networks, and family conflicts. The study also illuminated culturally and socio‐economically determined perceptions of social support and support‐seeking strategies. Limited personal resources and dwindling social networks are an impediment to coping with integration and settlement challenges. In many cases, newcomers’ efforts to seek help are thwarted by systemic obstacles. Newcomers experienced extensive unmet support needs, which service providers cannot adequately meet due to bureaucratic and resource constraints. Policies in various sectors that affect the lives of immigrants and refugees are inadequate for bridging their support deficiencies. These support gaps hinder the successful settlement and integration of newcomers. Policies and programs fostering culturally relevant support, and inter‐sectoral collaboration among organizations addressing the support needs of immigrants and refugees are timely.  相似文献   
90.
This paper addresses the issue of child protection protocols within research conducted with children. Based partly on primary data this paper raises questions about the role of ethics committees in defining the limits of confidentiality in relation to child protection protocols within research, the perceptions of both children and parents about the meanings of confidentiality and notions of ‘harm’, and the role of the researcher in relation to legal and professional guidance about the protection of vulnerable people in society. We explore the concept of confidentiality within a research setting from a child protection perspective. In doing so we examine the legal and moral obligations of researchers to report child protection concerns, how children themselves perceive ‘harm’, and the need for much clearer guidance to researchers, as well as child participants and parents, about the limitations of confidentiality.  相似文献   
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