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Contingency theory has had a strong influence in recent administration analysis and organization theory. Much of the previous work has been limited by the number of contingencies analyzed. This article reports on the findings from 56 Norwegian companies and attempts to analyze the contingencies of effectiveness, efficiency, innovation and satisfaction using the independent variables of environment, structure, technology, communication, motivation, decision making and job design. 相似文献
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This paper illustrates an approach to setting the decision framework for a study in early clinical drug development. It shows how the criteria for a go and a stop decision are calculated based on pre‐specified target and lower reference values. The framework can lead to a three‐outcome approach by including a consider zone; this could enable smaller studies to be performed in early development, with other information either external to or within the study used to reach a go or stop decision. In this way, Phase I/II trials can be geared towards providing actionable decision‐making rather than the traditional focus on statistical significance. The example provided illustrates how the decision criteria were calculated for a Phase II study, including an interim analysis, and how the operating characteristics were assessed to ensure the decision criteria were robust. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
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David Bremner Dan Chen John Iacono Stefan Langerman Pat Morin 《Statistics and Computing》2008,18(3):259-266
The Tukey depth (Proceedings of the International Congress of Mathematicians, vol. 2, pp. 523–531, 1975) of a point p with respect to a finite set S of points is the minimum number of elements of S contained in any closed halfspace that contains p. Algorithms for computing the Tukey depth of a point in various dimensions are considered. The running times of these algorithms
depend on the value of the output, making them suited to situations, such as outlier removal, where the value of the output
is typically small.
This research was partly funded by the NSERC Canada. 相似文献
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Pat Conway Ph.D. 《Journal of Family Social Work》2013,16(1):91-92
ABSTRACT For children in foster care, continued contact with biological parents may have significant implications. This article seeks to synthesize literature examining attachment theory and visitation between children in foster care and their parents. The results of the research synthesis indicate that although the exploration of attachment theory began over 40 years ago, the questions regarding the implications of foster care visitation and attachment continuation surprisingly remain unanswered. 相似文献
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The article presents the results of a nationwide study that examined the written criteria that is currently being used by graduate schools of social work for the appointment, retention, and promotion of their faculties. A content analysis of the study is discussed, and a unique behavioral model for the evaluation of faculty competence is offered. 相似文献
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Yiqing Ding Sean Duggan Matthew Ferranti Michael Jagadpramana Rushal Rege Yuriy Zhovtobryukh M.-Elisabeth Paté-Cornell 《Risk analysis》2020,40(4):842-857
The Europa mission approved in 2019 is still in the development phase. It is designed to conduct a detailed reconnaissance of that moon of Jupiter as it could possibly support life as we know it. This article is based on a top-down approach (mission → system → subsystems → components) to model the probability of mission failure. The focus here is on the case where the (uncertain) radiation load exceeds the (uncertain) capacity of critical subsystems of the spacecraft. The model is an illustrative quantification of the uncertainties about (1) the complex external radiation environment in repeated exposures, (2) the effectiveness of the shielding in different zones of the spacecraft, and (3) the components’ capacities, by modeling all three as dynamic random variables. A simulation including a sensitivity analysis is used to obtain the failure probability of the whole mission in forty-five revolutions around Jupiter. This article illustrates how probabilistic risk analysis based on engineering models, test results and expert opinions can be used in the early stages of the design of space missions when uncertainties are large. It also describes the optimization of the spacecraft design, taking into account the decisionmakers’ risk attitude and the mission resource constraints. 相似文献
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