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41.
We consider exact and approximate Bayesian computation in the presence of latent variables or missing data. Specifically we explore the application of a posterior predictive distribution formula derived in Sweeting And Kharroubi (2003), which is a particular form of Laplace approximation, both as an importance function and a proposal distribution. We show that this formula provides a stable importance function for use within poor man’s data augmentation schemes and that it can also be used as a proposal distribution within a Metropolis-Hastings algorithm for models that are not analytically tractable. We illustrate both uses in the case of a censored regression model and a normal hierarchical model, with both normal and Student t distributed random effects. Although the predictive distribution formula is motivated by regular asymptotic theory, it is not necessary that the likelihood has a closed form or that it possesses a local maximum.  相似文献   
42.
Relatively little attention has been paid to the use and importance of labels used by men who have sex with men to describe insertive or receptive sexual behavior during intercourse. This study examines sexual self-labels, sexual behavior, HIV transmission risk, and psychological functioning among 205 HIV-seropositive men who have sex with men. The majority of participants (88%) identified as a top, a bottom, or versatile. Tops were more likely to engage in insertive anal intercourse than bottoms, and bottoms were more likely to engage in receptive anal intercourse than tops, with versatiles reporting intermediate rates of both behaviors. Although the results suggest preliminary evidence regarding the predictive utility of self-labels, sexual behaviors of self-label groups were greatly overlapping. Differences were found among self-label groups in gay self-identification, internalized homophobia, sexual sensation seeking, and anxiety. Results suggest an added value in assessing self-labels in addition to asking about sexual behavior.  相似文献   
43.
Equity-based pay in the form of executive shareoptions (ESOs) is a controversial part of thetypical, US-style governance package, and ESOsin Germany are the focus of this paper. Aconventional view would see ESOs as a US-styleorganizational innovation diffusingglobally in general, and to Germany inparticular.As an alternative to innovation diffusion,however, a translation perspective wouldsuggest that the diffusion of apparentlysimilar governance devices around the worldhides the actual adoption of differentpractices.US/German comparative case studies arepresented as an empirical contribution thatgenerally shows a pattern so far consistentwith this translation view. In addition,intriguing and contrasting results are shownfor UK/German comparisons in the sense thatactual UK ESO plans are discovered to be moredistant from the US standard than German ones.  相似文献   
44.
In this paper we examine how leaders' perceptions of the instrumental benefits of abusive supervision shape their tendencies to abuse their employees. We posit that leaders who believe abuse has a positive impact on employee performance will engage in more abusive supervision than their peers, with downstream implications for employees' counterproductive work behaviors. Furthermore, we position leader empathic concern as a boundary condition, whereby empathic concern mitigates the effects of leaders' perceptions of abusive supervision's instrumentality. Data from two studies employing both experimental and field survey designs offer convergent support for our hypotheses. Overall, our findings challenge the prevailing view that abusive supervision is primarily motivated by a desire to aggress, instead demonstrating that leaders sometimes abuse their employees in the pursuit of more pro-organizational goals.  相似文献   
45.
Few studies have examined the role of religiosity and social capital on civic engagement in the context of a Muslim country. In this paper, we explore the impact of religiosity and social capital on charitable donations and volunteerism in Qatar. Drawing on a nationally representative survey from Qatar, we consider various attitudinal and behavioral measures for capturing religiosity and social capital. The results indicate that, even after controlling for a wide range of demographic variables, behavioral measures have a stronger effect than attitudes. Individuals who regularly perform daily prayers are more likely to donate than those individuals who simply describe themselves as religious. Similarly, individuals who are more active in their neighborhood engagement are more likely to volunteer than those who merely report high levels of social trust. These results suggest that when it comes to the relationship between religiosity, social capital and civic engagement, individual behavior is much more predictive than attitudes alone. We also find that even in the case of Qatar, where citizen wealth has rapidly increased in the last few decades, there is little evidence of substitution effects: citizens do not appear to trade-off or substitute between time and money. Instead, more religious and active citizens are likely to do both.  相似文献   
46.

Background

Australian midwives are regulated under the National Registration and Accreditation Scheme. Unregistered birth workers may provide midwifery services at homebirths without any regulatory oversight. To address this issue, several states have passed legislation enabling prohibition orders to be made (negative licensing) against unregistered health practitioners who fail to comply with a statutory code of conduct developed for those not covered by the National Scheme.

Aim

To explore the consequences for the availability of birth choices for women that arise from the introduction of negative licensing.

Discussion

An analysis of the regulatory framework and recent cases of unregistered birth workers attending homebirths reveals problems with equitable access to homebirth support, arising from issues with professional indemnity insurance, geography, and poor integration with hospitals and the wider healthcare system. These problems contribute to women choosing to employ the services of unregistered birth workers.

Conclusion

Negative licensing provides a useful additional tool for improving the safety of homebirths for mothers and babies, but it does not address the issues leading expectant parents to choose an unregistered birth worker to attend their births, and may contribute to an increase in high-risk behaviours, such as freebirthing.  相似文献   
47.
Most individuals will gamble during their lifetime, yet only a select few will develop gambling disorder. Gray’s Reinforcement Sensitivity Theory holds promise for providing insight into gambling disorder etiology and symptomatology as it ascertains that neurobiological differences in reward and punishment sensitivity play a crucial role in determining an individual’s affect and motives. The aim of the study was to assess a mediational pathway, which included patients’ sex, personality traits, reward and punishment sensitivity, and gambling-severity variables. The Sensitivity to Punishment and Sensitivity to Reward Questionnaire, the South Oaks Gambling Screen, the Symptom Checklist-Revised, and the Temperament and Character Inventory-Revised were administered to a sample of gambling disorder outpatients (N = 831), diagnosed according to DSM-5 criteria, attending a specialized outpatient unit. Sociodemographic variables were also recorded. A structural equation model found that both reward and punishment sensitivity were positively and directly associated with increased gambling severity, sociodemographic variables, and certain personality traits while also revealing a complex mediational role for these dimensions. To this end, our findings suggest that the Sensitivity to Punishment and Sensitivity to Reward Questionnaire could be a useful tool for gaining a better understanding of different gambling disorder phenotypes and developing tailored interventions.  相似文献   
48.
This article compares two different institutional models—state-sponsored rural partnerships and community-based development trusts—for engaging and empowering local communities in area-based regeneration, using the Isle of Wight as a case study. Following a critical review of the literature on community governance, we evaluate the effectiveness of community involvement in the Island's small towns through a comparison of the performance of the two development trusts in Cowes and Ryde, on the one hand, and that of the partnerships established under the Market Towns Initiative in Sandown, Shanklin and Ventnor, on the other. We conclude that both models reflect the structuring effect of central, regional and local state steering of the Island's regeneration policy community but also that a ‘development trust effect’ is observable in one location (Ryde), due to a capacity to stimulate new forms of community enterprise and to successfully alter political relationships within the local community. These findings support a ‘new institutionalist’ account of community empowerment which emphasises the importance of contextual variation and locally specific processes of institutionalisation rather than the determining effect of institutional design per se.  相似文献   
49.
50.
The adoption of The International Conference on Harmonization Tripartite Guideline: Statistical Principles for Clinical Trials (ICH-E9) has provided a foundation for the application of statistical principles in clinical research and raised awareness of the value of a statistical contribution to the wider pharmaceutical R&D process. In addition, over the past decade globalization of the pharmaceutical R&D process and the measures taken to address reduced productivity and spiralling costs have impacted on the roles and career opportunities for statisticians working in the pharmaceutical sector. This has enhanced the need for continuing professional development to equip statisticians with the skills to fully contribute to creating innovative solutions. In the future, key areas of focus are the establishment of professional standards for statistical work and increasing the collaboration between statisticians working in industry, regulatory agencies and academia. In addition, the diversity of roles and potential career paths for statisticians embarking on a career in the pharmaceutical sector emphasizes the importance of mentoring and coaching. For the more experienced statisticians, there are unprecedented opportunities to lead and innovate.  相似文献   
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