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141.
This report on practice discusses the pertinence of agile principles on the basis of the case “Universitätskolleg”, a central organisational unit of Universität Hamburg to promote the quality of studies and teaching. It describes previous experience with the framework scrum and the method Lean Kanban in mind. Odds and challenges of agile principles in university context are described and reflected and next steps are named.  相似文献   
142.
Before the fall of the Berlin Wall, mortality was considerably higher in the former East Germany than in West Germany. The gap narrowed rapidly after German reunification. The convergence was particularly strong for women, to the point that Eastern women aged 50–69 now have lower mortality despite lower incomes and worse overall living conditions. Prior research has shown that lower smoking rates among East German female cohorts born in the 1940s and 1950s were a major contributor to this crossover. However, after 1990, smoking behavior changed dramatically, with higher smoking intensity observed among women in the eastern part of Germany. We forecast the impact of this changing smoking behavior on East-West mortality differences and find that the higher smoking rates among younger East German cohorts will reverse their contemporary mortality advantage. Mortality forecasting methods that do not account for smoking would, perhaps misleadingly, forecast a growing mortality advantage for East German women. Experience from other countries shows that smoking can be effectively reduced by strict anti-smoking policies. Instead, East Germany is becoming an example warning of the consequences of weakening anti-smoking policies and changing behavioral norms.  相似文献   
143.
Non-heterosexual young women have a higher rate of unintended pregnancy than their heterosexual peers, but their fertility behaviors are understudied. We use longitudinal data from the Relationship Dynamics and Social Life study to investigate mechanisms contributing to non-heterosexual women’s higher pregnancy risk. These data include weekly reports of relationships, sex, and contraceptive use over 30 months. We compare the relationships and fertility behaviors of three groups: exclusively heterosexual (consistent heterosexual behavior, identity, and attraction); mostly heterosexual (heterosexual identity with same-sex behavior and/or same-sex attraction); and LGBTQ (any non-heterosexual identity). We find that mostly heterosexual and LGBTQ women behave differently from exclusively heterosexual women in ways likely to elevate their risk of unintended pregnancy: more distinct partners during the study period, more sexual intercourse with men, less frequent contraceptive use, less use of a dual method (condom plus hormonal method), and more gaps in contraceptive coverage. Mostly heterosexual women resemble LGBTQ women in their contraceptive behavior but have significantly more intercourse with men, which may increase their pregnancy risk relative to both LGBTQ and exclusively heterosexual women. We conclude by considering implications for LGBTQ health and the measurement of sexual minority populations.  相似文献   
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The world is ageing both at an individual and a population level, and population ageing is truly a global phenomenon. Life expectancies at birth have increased at the global level from 47 years in the mid-20th century to around 70 years today, and are expected to rise to 76 years by the mid-21st century. The proportion of the world’s population aged 60 years and over has increased from 8 % in the mid-20th century to 12 %, and by 2050 it is expected to reach 21 %. The emergence of large numbers of centenarians has accompanied this development. This paper outlines this emergence historically and the likely growth in the number of centenarians in the 21st century, in particular in England and Wales, analysing mortality trends since 1840 and the rise in the number of centenarians in the 20th and 21st centuries. The number of centenarians in England and Wales increased from around 160 in 1922 to almost 12,500 by 2012, but if mortality at all ages had remained constant from 1912 to 2012, then by 2012 the number of centenarians would only have been around 720. By 2100, the number of centenarians is expected to reach around 1.4 million, but if future mortality at all ages were to remain constant, then by 2100 the number of centenarians would be around 78,000. However, if predicted mortality for those aged 55 years and over was to decrease by an additional 5 % every 5 years until 2100, then the number of centenarians in England and Wales would reach around 1.8 million by the end of the century.  相似文献   
147.
The objective of this study is to analyze the aspects that allowed a critical part of Social Economy Organizations (SEOs) to survive a recession period, especially participation in collaborative networks. The financial stress of an SEO will depend on the resources and capabilities available to the organization. To analyze the financial stress of Spanish SEOs, we defined a sample of 714 SEOs. Approximately half of these organizations suffered from financial stress in the analyzed period (2009–2012). The results obtained in this study reveal the existence of three factors that distinguish organizations under financial stress: (a) a high dependence on government funding; (b) changes in the relationship between staff and volunteers; and (c) a lack of access to markets. The combination of these three elements results in an unsustainable situation for the organization. The development of a collaborative profile increases the SEO’s probability of surviving the adverse manifestations of its environment.  相似文献   
148.
We consider the task of generating discrete-time realisations of a nonlinear multivariate diffusion process satisfying an Itô stochastic differential equation conditional on an observation taken at a fixed future time-point. Such realisations are typically termed diffusion bridges. Since, in general, no closed form expression exists for the transition densities of the process of interest, a widely adopted solution works with the Euler–Maruyama approximation, by replacing the intractable transition densities with Gaussian approximations. However, the density of the conditioned discrete-time process remains intractable, necessitating the use of computationally intensive methods such as Markov chain Monte Carlo. Designing an efficient proposal mechanism which can be applied to a noisy and partially observed system that exhibits nonlinear dynamics is a challenging problem, and is the focus of this paper. By partitioning the process into two parts, one that accounts for nonlinear dynamics in a deterministic way, and another as a residual stochastic process, we develop a class of novel constructs that bridge the residual process via a linear approximation. In addition, we adapt a recently proposed construct to a partial and noisy observation regime. We compare the performance of each new construct with a number of existing approaches, using three applications.  相似文献   
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A new numerical method to solve the downdating problem (and variants thereof), namely removing the effect of some observations from the generalized least squares (GLS) estimator of the general linear model (GLM) after it has been estimated, is extensively investigated. It is verified that the solution of the downdated least squares problem can be obtained from the estimation of an equivalent GLM, where the original model is updated with the imaginary deleted observations. This updated GLM has a non positive definite dispersion matrix which comprises complex covariance values and it is proved herein to yield the same normal equations as the downdated model. Additionally, the problem of deleting observations from the seemingly unrelated regressions model is addressed, demonstrating the direct applicability of this method to other multivariate linear models. The algorithms which implement the novel downdating method utilize efficiently the previous computations from the estimation of the original model. As a result, the computational cost is significantly reduced. This shows the great usability potential of the downdating method in computationally intensive problems. The downdating algorithms have been applied to real and synthetic data to illustrate their efficiency.  相似文献   
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