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31.
The paper analyses the distribution of times from HIV seroconversion to the first AIDS defining illness for a subcohort of the Western Australian HIV Cohort Study for whom the seroconversion date is known to fall within a calendar time window. The analysis is based on a generalised gamma model for the incubation times and a piecewise constant distribution for the conditional times of seroconversion given the seroconversion windows. This allows flexible hazard shapes and also allows comparison of goodness of fit of the gamma and Weibull distributions which are often used for modelling incubation times. Computational issues are discussed. In these data, neither age at seroconversion, nor calendar time of seroconversion, nor the identification of a seroconversion illness appears to afFect incubation distributions. The Weibull distribution appears to provide a reasonable fit. The distribution of times from seroconversion to an HIV-related death is also briefly considered.  相似文献   
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I consider nonparametric identification of nonseparable instrumental variables models with continuous endogenous variables. If both the outcome and first stage equations are strictly increasing in a scalar unobservable, then many kinds of continuous, discrete, and even binary instruments can be used to point‐identify the levels of the outcome equation. This contrasts sharply with related work by Imbens and Newey, 2009 that requires continuous instruments with large support. One implication is that assumptions about the dimension of heterogeneity can provide nonparametric point‐identification of the distribution of treatment response for a continuous treatment in a randomized controlled experiment with partial compliance.  相似文献   
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Prolapse is an extremely common condition, for which 11% of women will have a surgical procedure at some point in their lives. The recurrence rate after most of the traditional surgical procedures is high and upto 29% of women who have had surgery for prolapse will require a further operation. In order to improve the surgical outcome, there is currently much interest in the use of grafts to augment traditional repairs and new procedures have been developed using specifically developed grafts. These have been combined with minimally invasive surgical techniques in an attempt to reduce surgical morbidity. These procedures may improve the outcome of surgery for prolapse. However, there is currently a lack of long-term data from randomized trials to demonstrate their effectiveness and safety.  相似文献   
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The proportion of young people taken into the care of the state has increased recently and there is evidence that this social group suffer negative long‐term outcomes that might be conceptualised by the emergent criminological category of ‘social harm’. Debates in social work around an ethics of care and justice offer different ways of thinking about responding to social harm. This paper reports findings from an innovative arts‐based intervention with Looked After Children and young people and concludes that holding these competing value sets in creative tension is central to the success of the programme in helping young people to cope with and contest social harm.  相似文献   
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Review of Economics of the Household - Two theories of intimate partner violence (IPV) have differing predictions on how women’s bargaining power affects rates of IPV. If an abuser enjoys and...  相似文献   
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