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Previous studies of the apparent influence of daylight level and hour changes on the incidence of road casualties are reviewed and refined, by analysis of official databases for Great Britain (1969–1973 and 1985–1994) and the USA (1991–1995). New statistical methods, based on precisely computed altitudes of the sun for each accident location, are used to model casualty frequencies aggregated by week and hour of day, and locally evaluated associations between individual casualty incidence and solar altitude. Estimates of the altitude factor are interpreted causally to give counterfactual estimates of the effect of different clock time schedules on countrywide casualty numbers.  相似文献   
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Sociological Forum -  相似文献   
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This study examined the influence offamily-responsive variables and the moderating influence of gender on the retention-relevant outcomes of organizational commitment and turnover intentions. Data were obtained with the aid of structured questionnaires from employed parents (N = 228) in a human service authority in Hong Kong. Results of regression analysis revealed that satisfaction with work schedule flexibility and supervisor work family support were related to both retention-relevant outcomes. Contrary to our prediction, gender did not moderate the influence of any of the family-responsive variables on the retention-relevant outcomes. Limitations of the study, directions for future research and implications of the findings for enhancing the effectiveness of family-responsive human resource policies are discussed.  相似文献   
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State Medicaid programs have expanded home and community-based services (HCBS). This article compares trends and variations in state policies for Medicaid HCBS programs in 2005 and 2010. State limitations on financial eligibility criteria and service benefits have remained stable. Although the use of consumer direction, independent providers, and family care providers has increased, some states do not have these options. The increased adoption of state cost control policies have led to large increases in persons on waiver wait lists. Access could be improved by standardizing and liberalizing state HCBS policies, but state fiscal concerns are barriers to rebalancing between HCBS and institutional services.  相似文献   
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Many oncology studies incorporate a blinded independent central review (BICR) to make an assessment of the integrity of the primary endpoint, progression free survival. Recently, it has been suggested that, in order to assess the potential for bias amongst investigators, a BICR amongst only a sample of patients could be performed; if evidence of bias is detected, according to a predefined threshold, the BICR is then assessed in all patients, otherwise, it is concluded that the sample was sufficient to rule out meaningful levels of bias. In this paper, we present an approach that adapts a method originally created for defining futility bounds in group sequential designs. The hazard ratio ratio, the ratio of the hazard ratio (HR) for the treatment effect estimated from the BICR to the corresponding HR for the investigator assessments, is used as the metric to define bias. The approach is simple to implement and ensures a high probability that a substantial true bias will be detected. In the absence of bias, there is a high probability of accepting the accuracy of local evaluations based on the sample, in which case an expensive BICR of all patients is avoided. The properties of the approach are demonstrated by retrospective application to a completed Phase III trial in colorectal cancer. The same approach could easily be adapted for other disease settings, and for test statistics other than the hazard ratio. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
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Formative research is often required for program planning, and for reducing uncertainty about generalizability of program effects. This article describes and justifies methods of formative research conducted for the REACT study (Rapid Early Action for Coronary Treatment), a multi-center collaborative randomized community trial aimed at reducing patient delay in seeking care for acute myocardial infarction (AMI). Formative research cast light on patient and community members’ decision-making process in seeking help for AMI, as well as barriers and facilitators of this process. Investigators at all five REACT Field Centers participated in the formative research. The process consisted of: (1) developing a common theoretical framework for the study intervention; (2) conducting a literature review and qualitative research to identify and address gaps in knowledge; and (3) developing a common protocol for the REACT study that accommodated the diversity of the target communities in terms of services, resources, history, and ethnicity. Analysis employed triangulation, defined as an explicit search for heterogeneous data sources to reduce uncertainty about forces at work and opportunities for intervention across settings and populations. Because the collection and interpretation of data went in stages, staff of several REACT Field Centers had independent input to the overall synthesis, then shared and revised the results. Advantages and limitations of this approach are discussed.  相似文献   
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The present paper evaluates relevant findings on long- and short-term affective states in subjective well-being and argues for a componential model that combines the two into the more general concept of happiness. Two age parameters, one for long-term and one for short-term affect are added to the simple model to account for age changes in happiness. Measures of long- and short-term affect are presented, as is a paradigm for separating the components. Support for the simple model is provided by an experimental investigation with 64 college students who were exposed to positive and/or negative mood induction. As expected, the induction had substantially greater effect on short- than on long-term affect measures, particularly the negative induction procedure. These findings are consistent with predictions. However, multiple age cohorts will have to be assessed within a longitudinal framework to obtain values for the age parameters.  相似文献   
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