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111.
"高铁经济"的发展对区域经济与社会发展具有重要的带动作用与战略意义,高铁枢纽及其周边地区也将成为城市发展新引擎。对其功能定位与产业发展则是高铁枢纽地区开发建设的前提与成功与否的关键因素之一。以广州南站枢纽地区为例,以区域竞合发展的视角,剖析南站地区发展面临的阶段困境,探索基于新一轮国家对外开放战略与地区合作升级机遇的背景下,南站地区如何利用高铁枢纽和区位优势,对接不同层面的战略需求来清晰定位其功能,并对产业发展路径与空间布局提出相应的合理化建议。  相似文献   
112.
Youth’s perceptions of peer norms have profound effects on their attitudes and behaviors. Unfortunately, their perceptions of peers tend to be biased. To investigate the role of media in the formation of misperceived peer norms, the current study tested and compared two media-effect mechanisms: the direct exemplar mechanism and the indirect influence of presumed influence (IPI) mechanism. The two mechanisms were tested in a sample (n = 1746) that is representative of college students in one large university in China, based on which the actual and perceived campus smoking rates were examined. The individual-level perceived peer smoking prevalence was then analyzed in comparison with the campus-level actual smoking prevalence. The results revealed serious overestimations of peer smoking prevalence. As predicted, pro-smoking media content significantly heightened smoking prevalence estimates through both exemplar and IPI mechanisms. In contrast, anti-smoking messages did not elicit any intended effect through the IPI mechanism, but showed a boomerang effect through the exemplar mechanism. These findings suggest that both pro- and anti-smoking media content may be responsible for inflated perceptions of peer smoking among youth.  相似文献   
113.
The varying coefficient (VC) model introduced by Hastie and Tibshirani [26 T. Hastie and R. Tibshirani, Varying-coefficient models, J. R. Statist. Soc. (Ser. B) 55 (1993), pp. 757796.[Web of Science ®] [Google Scholar]] is arguably one of the most remarkable recent developments in nonparametric regression theory. The VC model is an extension of the ordinary regression model where the coefficients are allowed to vary as smooth functions of an effect modifier possibly different from the regressors. The VC model reduces the modelling bias with its unique structure while also avoiding the ‘curse of dimensionality’ problem. While the VC model has been applied widely in a variety of disciplines, its application in economics has been minimal. The central goal of this paper is to apply VC modelling to the estimation of a hedonic house price function using data from Hong Kong, one of the world's most buoyant real estate markets. We demonstrate the advantages of the VC approach over traditional parametric and semi-parametric regressions in the face of a large number of regressors. We further combine VC modelling with quantile regression to examine the heterogeneity of the marginal effects of attributes across the distribution of housing prices.  相似文献   
114.
High-content automated imaging platforms allow the multiplexing of several targets simultaneously to generate multi-parametric single-cell data sets over extended periods of time. Typically, standard simple measures such as mean value of all cells at every time point are calculated to summarize the temporal process, resulting in loss of time dynamics of the single cells. Multiple experiments are performed but observation time points are not necessarily identical, leading to difficulties when integrating summary measures from different experiments. We used functional data analysis to analyze continuous curve data, where the temporal process of a response variable for each single cell can be described using a smooth curve. This allows analyses to be performed on continuous functions, rather than on original discrete data points. Functional regression models were applied to determine common temporal characteristics of a set of single cell curves and random effects were employed in the models to explain variation between experiments. The aim of the multiplexing approach is to simultaneously analyze the effect of a large number of compounds in comparison to control to discriminate between their mode of action. Functional principal component analysis based on T-statistic curves for pairwise comparison to control was used to study time-dependent compound effects.  相似文献   
115.
116.
In semidefinite programming (SDP), we minimize a linear objective function subject to a linear matrix being positive semidefinite. A powerful program, SeDuMi, has been developed in MATLAB to solve SDP problems. In this article, we show in detail how to formulate A-optimal and E-optimal design problems as SDP problems and solve them by SeDuMi. This technique can be used to construct approximate A-optimal and E-optimal designs for all linear and nonlinear regression models with discrete design spaces. In addition, the results on discrete design spaces provide useful guidance for finding optimal designs on any continuous design space, and a convergence result is derived. Moreover, restrictions in the designs can be easily incorporated in the SDP problems and solved by SeDuMi. Several representative examples and one MATLAB program are given.  相似文献   
117.
Quality of life is a complicated concept that has attracted broad attention from multiple disciplines. This article introduces a set of studies that employ diverse approaches to explore how work, vocational, and career experiences shape quality of life among migrants, and proposes a future agenda to extend this stream of research. Specifically, operationalizing quality of life in different ways, research showcased in this special issue has demonstrated how international and intranational migrants achieve, maintain, and enhance their well-being in different life domains. Reflecting on the literature and the showcased studies, this article proposes that future research should advance the current inquiry by better categorizing vocational experiences, uniquely operationalizing of quality of life in migration contexts, taking a more culturally sensitive perspective, and broadening methodological approaches.  相似文献   
118.
In recent years, population health research has focused on understanding the determinants of later-life health. Two strands of that work have focused on (1) international comparisons of later-life health and (2) assessing the early-life origins of disease and disability and the importance of life course processes. However, the less frequently examined intersection of these approaches remains an important frontier. The present study contributes to the integration of these approaches. We use the Health and Retirement Study family of data sets and a cohort dynamic approach to compare functional health trajectories across 12 high-income countries and to examine the role of life course processes and cohort dynamics in contributing to variation in those trajectories. We find substantial international variation in functional health trajectories and an important role of cohort dynamics in generating that variation, with younger cohorts often less healthy at comparable ages than the older cohorts they are replacing. We further find evidence of heterogeneous effects of life course processes on health trajectories. The results have important implications for future trends in morbidity and mortality as well as public policy.  相似文献   
119.
Over the past decade, health insurance coverage has expanded dramatically in China. Health insurance benefits, however, remain shallow or ambiguous. This study examines the effect of Chinese national health insurance policy on health service utilization and economic burden in urban settings using the Urban Resident Basic Medical Insurance Household Survey. We employ the Heckman selection model to correct for selection bias among hospital inpatients, and find that compared to individuals without health insurance, those with health insurance are more likely to be admitted to the hospital when their physicians recommended them to enter the hospital as inpatients. Health insurance is also associated with about 45.6 % decrease in out-of-pocket inpatient expenditures. Individuals with urban employee basic medical insurance see the largest decrease in economic burden, followed by individuals with urban resident basic medical Insurance, and those with new rural cooperative medical insurance.  相似文献   
120.
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