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51.
本文提出用复模态影响系数来解决转了大衡的在线以别和诊断问题,讨论了影响系数矩阵的力学意义.试验中可不加试重求出影响系数,并编制了相应的计算程序.  相似文献   
52.
In this paper, the notion of average total inspection (ATI) is introduced to ChSP-4(c1,c2) sampling plans. Procedures have been developed for the construction and selection of ChSP-4(c1, c2 plans, minimizing ATI at a given process average, while protection to the consumer is given in terms of the (i) average outgoing quality limit and (ii) limiting quality level.A wide range of c1 and c2 values are considered for developing tables which cover almost all practical situations. The procedure described is similar to that of Dodge and Romig.  相似文献   
53.
培养学生用英语进行交际的能力是大学英语教学的重点。要提高学生的交际能力 ,就要注意学生听说能力的培养 ,这需要我们教师从课堂教学入手。  相似文献   
54.
农业在国民经济中的重要性众所周知。本文通过对最能体现农业重要性的例子、四大文明的诞生和英国的工业革命等人类文明史的阐述,用哲学的思维对当代中国的农业、农村、农民做了初步的探讨。  相似文献   
55.
The benchmark dose (BMD) is an exposure level that would induce a small risk increase (BMR level) above the background. The BMD approach to deriving a reference dose for risk assessment of noncancer effects is advantageous in that the estimate of BMD is not restricted to experimental doses and utilizes most available dose-response information. To quantify statistical uncertainty of a BMD estimate, we often calculate and report its lower confidence limit (i.e., BMDL), and may even consider it as a more conservative alternative to BMD itself. Computation of BMDL may involve normal confidence limits to BMD in conjunction with the delta method. Therefore, factors, such as small sample size and nonlinearity in model parameters, can affect the performance of the delta method BMDL, and alternative methods are useful. In this article, we propose a bootstrap method to estimate BMDL utilizing a scheme that consists of a resampling of residuals after model fitting and a one-step formula for parameter estimation. We illustrate the method with clustered binary data from developmental toxicity experiments. Our analysis shows that with moderately elevated dose-response data, the distribution of BMD estimator tends to be left-skewed and bootstrap BMDL s are smaller than the delta method BMDL s on average, hence quantifying risk more conservatively. Statistically, the bootstrap BMDL quantifies the uncertainty of the true BMD more honestly than the delta method BMDL as its coverage probability is closer to the nominal level than that of delta method BMDL. We find that BMD and BMDL estimates are generally insensitive to model choices provided that the models fit the data comparably well near the region of BMD. Our analysis also suggests that, in the presence of a significant and moderately strong dose-response relationship, the developmental toxicity experiments under the standard protocol support dose-response assessment at 5% BMR for BMD and 95% confidence level for BMDL.  相似文献   
56.
What do we mean by progress and cumulation in the social and human sciences? Recent thinking in the philosophy and history of science has led to an abandonment of some versions of logical positivism and of verificationism that had a strong deductive and theory testing orientation. What is to replace them is less clear. This paper argues that progress and cumulation can be seen as a process of evaluation and retention within an epistemic community. Scholarly disciplines differ in their social structure and in their epistemic and normative commitments. Since sociology is a fragmented discipline, progress and cumulation differ within its multiple subdisciplines, which to varying extents represent epistemic communities. Brief sketches of progress (advance) and cumulation in several subdisciplines are offered.  相似文献   
57.
The skin is a route of exposure that needs to be considered when conducting a risk assessment. It is necessary to identify the potential for dermal penetration by a chemical as well as to determine the overall importance of the dermal route of exposure as compared with inhalation or oral routes of exposure. The physical state of the chemical, vapor or liquid, the concentration, neat or dilute, and the vehicle, lipid or aqueous, is also important. Dermal risk is related to the product of the amounts of penetration and toxicity. Toxicity involves local effects on the skin itself and the potential for systemic effects. Dermal penetration is described in large part by the permeability constant. When permeability constants are not known, partition coefficients can be used to estimate a chemical's potential to permeate the skin. With these concepts in mind, a tiered approach is proposed for dermal risk assessment. A key first step is the determination of a skin-to-air or skin-to-medium partition coefficient to estimate a potential for dermal absorption. Building a physiologically-based pharmacokinetic (PBPK) model is another step in the tiered approach and is useful prior to classical in vivo toxicity tests. A PBPK model can be used to determine a permeability constant for a chemical as well as to show the distribution of the chemical systemically. A detailed understanding of species differences in the structure and function of the skin and how they relate to differences in penetration rates is necessary in order to extrapolate animal data from PBPK models to the human. A study is in progress to examine anatomical differences for four species.  相似文献   
58.
The 1995 wave of the Add Health study is used to investigate the relative influence of parent gender and residence on patterns of parental involvement with adolescents. Adolescent reports (N =17,330) of shared activities, shared communication, and relationship quality with both biological parents are utilized. A multidimensional scaling analysis reveals that parent gender explains most of the variance in parent‐adolescent involvement, with residential status playing a secondary yet a fundamental role in accounting for these patterns. Resident mothers who do not live with adolescents’ biological fathers engage in the broadest range of activities with their children. Unpartnered resident fathers display patterns of parenting that are as similar to mothers as they are to other fathers.  相似文献   
59.
Are the decisions of American policymakers informed by generaltrends in the public’s ideology or by the public’spolicy-specific preferences? In this article we discuss twoexplanations for the types of public opinion information thatpoliticians collect and use. Using a unique data set of privatepolls from the White House of Richard Nixon, we find that whenopinion data on specific policies were available, the presidentrelied on them and not on general ideology data. On less importantissues, however, we find that the president often chose notto collect policy-specific data and instead relied on generalideology data. The differential collection and use of informationby policymakers reflect varying strategic calculations. Theyalso have profound implications for representative democracyand the demands placed on citizens and governors.  相似文献   
60.
:以费秀元、费金绶父子为首的周庄枪匪集团 ,是清末太湖地区众多枪匪中势力较大的一支。费氏通过捐输取得官衔、功名 ,约束土匪劣性 ,获地主士绅和清政府的支持。太平军攻占苏州后 ,该集团负隅顽抗 ,继而被迫假意受抚 ,最终公开投降清军。在李鸿章率淮军攻占太平天国苏福省的战斗中 ,周庄枪匪绘呈地图、担任向导、随军作战 ,出力颇巨 ,后为李鸿章收编。  相似文献   
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