Maximum likelihood estimation of Laplace parameters based on general type-II censored examples

In this paper, we derive the maximum likelihood estimators of the parameters of a Laplace distribution based on general Type-II censored samples. The resulting explicit MLE's turn out to be simple linear functions of the order statistics. We then examine the asymptotic variance of the estimates by calculating the elements of the Fisher information matrix.     

Do Interactions Between Environmental Chemicals and the Human Microbiome Need to Be Considered in Risk Assessments?

One of the most dynamic and fruitful areas of current health‐related research concerns the various roles of the human microbiome in disease. Evidence is accumulating that interactions between substances in the environment and the microbiome can affect risks of disease, in both beneficial and adverse ways. Although most of the research has concerned the roles of diet and certain pharmaceutical agents, there is increasing interest in the possible roles of environmental chemicals. Chemical risk assessment has, to date, not included consideration of the influence of the microbiome. We suggest that failure to consider the possible roles of the microbiome could lead to significant error in risk assessment results. Our purpose in this commentary is to summarize some of the evidence supporting our hypothesis and to urge the risk assessment community to begin considering and influencing how results from microbiome‐related research could be incorporated into chemical risk assessments. An additional emphasis in our commentary concerns the distinct possibility that research on chemical–microbiome interactions will also reduce some of the significant uncertainties that accompany current risk assessments. Of particular interest is evidence suggesting that the microbiome has an influence on variability in disease risk across populations and (of particular interest to chemical risk) in animal and human responses to chemical exposure. The possible explanatory power of the microbiome regarding sources of variability could reduce what might be the most significant source of uncertainty in chemical risk assessment.     

Exploring Nonnormative Coresidence in Urban China: Living With Wives’ Parents

We model histories between two cohorts of urban Chinese couples (N = 1,191) of a rarely studied living arrangement—coresidence with the wife's parents—using a dynamic life history analysis in contrast to previous cross‐sectional studies of coresidence. We examine patterns of entry into and exit from coresidence with the wife's parents, comparing the predictive power of modernization theory to the effect of demographic change and the resources and needs of each generation. Given China's well‐known patrilineal family system, we find a surprisingly high number of couples ever residing nonnormatively, and significant differences between cohorts in what determines the pattern of coresidence. Resources and needs that reflect conscious choices to coreside most strongly influence nonnormative coresidence. Its importance may increase as the children of the One‐Child Family Policy grow up and marry.     

The Victim of Rape: WHAT Progress?

This article utilizes a recent statement made by a member of the judiciary, in which female 'hitch-hikers' are admonished on the basis that such behaviour is likely to provoke a sexual assault. The attitudes, recent research and genesis of sex-role stereotypes are explored in order to elucidate the rationale underlying this statement. Particular attention is drawn to the fact that such statements are addressed exclusively to females.     

Symbiotic mothers and infantilized only children: A subtype of single-parent family

One single-parent family pattern is the enmeshed mother/onlychild dyad. Women marry to have children, and then divorce, while mother and child live out the reciprocally gratifying symbiotic period. When these mothers hamper offspring moves toward separation-individuation, post-divorce difficulties bring them to treatment. These difficulties are distinct from those found in other single-parent families. Intervention can move mother and child from the prolonged symbiosis. Treatment stresses modification of low maternal selfesteem, and correction of pathogenic maternal behavior. Re-introduction of the father to the system can also free both mother and child for further growth.     

Assessing clinical progress: A case study of Daryl

In this single case study, the authors conceptually framed their understanding of dissociation and splitting as defensive/adaptive coping mechanisms through which children respond to abusive/neglectful environments and the developmental deficits of abused/neglected children as related to failure in separation/individuation. Case study methodology with a nested experimental research design employed content analysis of process recordings to identify targeted defenses and developmental themes and then to assess therapeutic effectiveness during the first six months of psychodynamic play therapy with Daryl. In-session cliniial progress was assessed through charting changes in defenses and developmental themes, identifying degree of goal achievement, and clinically observing treatment stage progression. Visual analysis of the frequency charts identified a slight cyclical decline in use of splitting and guarding against dissociation and a somewhat uneven increase in the developmental theme of coexistence/integration. While these changes in targeted outcome variables were not statistically significant, the amount of change did exceed the predetermined outcome goals for decreased splitting and increased coexistence but not the goal of decreased guarding against dissociation. Review of the process recordings also identified clear markers of treatment progression through two therapeutic stages in the first six months of long term psychodynamic play therapy and further supported the clinical meaningfulness of the observed changes.