浅析江户时期西方医学在日本的传播

江户时期,荷兰成为唯一与日本交往的西方国家,进而荷兰成为西方文化传进日本的通道,其中以医学最为瞩目.西方医学在日本的传播使得日本"兰学"兴起,并为日本的近代化奠定了科学基础.这一时期,医学主要通过荷兰商馆医生口述、江户参府、日本翻译西方书籍、开办西医学塾等方式传播.     

论封龙山文化的形成与内涵

封龙山作为“燕赵文化名山”,有着悠久的历史传承和厚重的文化底蕴。封龙山文化的形成首先与毗邻曾为政治、经济、文化中心的特殊地理位置有关,其次是它对周边地区的广泛影响而形成了人才辈出群星璀璨的局面。封龙山作为中国古代传统文化的重要发祥地之一,为中华文明做出了卓越的贡献,并在以后封龙山文化在不断发展的过程中,表现出了极大的包融性,其丰富的文化内涵体现于三个方面：科学与信仰相容、 佛教与道教双修、修德与崇礼共存。     

Subgroup Analysis with Time‐to‐Event Data Under a Logistic‐Cox Mixture Model

Subgroup detection has received increasing attention recently in different fields such as clinical trials, public management and market segmentation analysis. In these fields, people often face time‐to‐event data, which are commonly subject to right censoring. This paper proposes a semiparametric Logistic‐Cox mixture model for subgroup analysis when the interested outcome is event time with right censoring. The proposed method mainly consists of a likelihood ratio‐based testing procedure for testing the existence of subgroups. The expectation–maximization iteration is applied to improve the testing power, and a model‐based bootstrap approach is developed to implement the testing procedure. When there exist subgroups, one can also use the proposed model to estimate the subgroup effect and construct predictive scores for the subgroup membership. The large sample properties of the proposed method are studied. The finite sample performance of the proposed method is assessed by simulation studies. A real data example is also provided for illustration.     

Validation of Nonparametric Two-sample Bootstrap in ROC Analysis on Large Datasets

The nonparametric two-sample bootstrap is applied to computing uncertainties of measures in receiver operating characteristic (ROC) analysis on large datasets in areas such as biometrics, speaker recognition, etc. when the analytical method cannot be used. Its validation was studied by computing the standard errors of the area under ROC curve using the well-established analytical Mann–Whitney statistic method and also using the bootstrap. The analytical result is unique. The bootstrap results are expressed as a probability distribution due to its stochastic nature. The comparisons were carried out using relative errors and hypothesis testing. These match very well. This validation provides a sound foundation for such computations.     

Stochastically optimal bootstrap sample size for shrinkage-type statistics

In nonregular problems where the conventional \(n\) out of \(n\) bootstrap is inconsistent, the \(m\) out of \(n\) bootstrap provides a useful remedy to restore consistency. Conventionally, optimal choice of the bootstrap sample size \(m\) is taken to be the minimiser of a frequentist error measure, estimation of which has posed a major difficulty hindering practical application of the \(m\) out of \(n\) bootstrap method. Relatively little attention has been paid to a stronger, stochastic, version of the optimal bootstrap sample size, defined as the minimiser of an error measure calculated directly from the observed sample. Motivated by this stronger notion of optimality, we develop procedures for calculating the stochastically optimal value of \(m\). Our procedures are shown to work under special forms of Edgeworth-type expansions which are typically satisfied by statistics of the shrinkage type. Theoretical and empirical properties of our methods are illustrated with three examples, namely the James–Stein estimator, the ridge regression estimator and the post-model-selection regression estimator.     

公平合理利用原则在国际水法中的适用局限及其反思

作为国际水法的基本原则,公平合理利用原则具有条约法及习惯法的规范基础,并且可指导跨界水道的利用及水资源分配,但是其抽象性及模糊性降低了适用的确定性。公平合理利用原则适用的局限性主要表现为理论基础不成熟,概念难以统一明确,非排他性考虑因素多元但无优先次序等方面。对公平合理利用原则的反思要求充分尊重跨界水道的自然特性,遵从不造成重大损害原则及国际合作原则,厘清相关考虑因素的优先次序,推动建立水道国家的利益共识,从而实现流域国家对跨界水道的公平合理利用。      

英汉“上／下”方位隐喻的认知文化对比分析

许多抽象概念的认知需借助于方位隐喻.由"上/下(up / down)"域产生的隐喻是应用最普遍的一种方位隐喻,它以"上/下(up / down)"的空间意义为核心拓展出一系列丰富的隐喻意义.本文对英汉方位隐喻中的"上/下"源域进行初步探讨,分析其认知基础,并深入剖析英汉语中"上/下"方位隐喻差异及其认知、文化根源     

地方高校服务乡村振兴的逻辑理路

乡村振兴是新时代党和国家解决“三农”问题,实现城乡统筹发展的重要途径,关系着中华民族伟大复兴中国梦的实现。地方高校作为区域人才培养的主阵地、知识生产创新的主渠道,服务乡村振兴既是内在要求,更是职责使命。研究指出,探讨地方高校服务乡村振兴的个性、共性内涵,以及历史发展脉络,是理解地方高校“何以要”服务乡村振兴的关键;而探讨地方高校服务乡村振兴的理论依据,以及实践经验,是打开地方高校“何以能”服务乡村振兴大门的钥匙。研究从内生逻辑、历史逻辑、理论逻辑和实践逻辑四个维度,明晰了地方高校“何以要”和“何以能”服务乡村振兴的逻辑理路,为地方高校高质量服务乡村振兴提供理论和实践参考。     

试论清朝初期对侗族地区土司的管理

清朝初期,清政府十分重视对侗族地区土司的管理。广加招徕,准予承袭,制定并施行一系列严密的管理措施。这对于稳定和巩固西南边疆,起了重要的作用。随着侗族地区土司制度的腐朽,其弊端日渐显露,为雍正时期清政府于此进行改土归流提供了条件。