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Comparison of accuracy between two diagnostic tests can be implemented by investigating the difference in paired Youden indices. However, few literature articles have discussed the inferences for the difference in paired Youden indices. In this paper, we propose an exact confidence interval for the difference in paired Youden indices based on the generalized pivotal quantities. For comparison, the maximum likelihood estimate‐based interval and a bootstrap‐based interval are also included in the study for the difference in paired Youden indices. Abundant simulation studies are conducted to compare the relative performance of these intervals by evaluating the coverage probability and average interval length. Our simulation results demonstrate that the exact confidence interval outperforms the other two intervals even with small sample size when the underlying distributions are normal. A real application is also used to illustrate the proposed intervals. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
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国内外学者对我国GDP数据质量的质疑重点已从年度数据转到季度数据,从全国数据转向地方数据。本文通过设计一套较为系统且可操作性强的季度GDP评估指标体系,运用空间面板数据模型对各省区的季度GDP数据质量进行了实证检验。结果表明,整体来看,中国各省区季度GDP同各经济指标的匹配性较好,数据质量较高,并不存在明显的失真现象;从时间上来看,每年一、二季度的GDP存在一定程度的高估,而每年三、四季度的GDP则存在一定程度的低估,但是这种偏差在统计上不显著;分地区来看,尽管一半省区的季度GDP存在一定程度的高估,另一半省区存在一定程度的低估,但大部分省区高估或低估的程度在统计上不显著。文章进一步分析了其中的原因。 相似文献
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For Canada's boreal forest region, the accurate modelling of the timing of the appearance of aspen leaves is important to forest fire management, as it signifies the end of the spring fire season that occurs after snowmelt. This article compares two methods, a midpoint rule and a conditional expectation method used to estimate the true flush date for interval-censored data from a large set of fire-weather stations in Alberta, Canada. The conditional expectation method uses the interval censored kernel density estimator of Braun et al. (2005). The methods are compared via simulation, where true flush dates were generated from a normal distribution and then converted into intervals by adding and subtracting exponential random variables. The simulation parameters were estimated from the data set and several scenarios were considered. The study reveals that the conditional expectation method is never worse than the midpoint method, and that there is a significant advantage to this method when the intervals are large. An illustration of the methodology applied to the Alberta data set is also provided. 相似文献
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ABSTRACTDiscrepancies are measures which are defined as the deviation between the empirical and the theoretical uniform distribution. In this way, discrepancy is a measure of uniformity which provides a way of construction a special kind of space filling designs, namely uniform designs. Several discrepancies have been proposed in recent literature. A brief, selective review of these measures including some construction algorithms are given in this paper. Furthermore, a critical discussion along with some comparisons is provided, as well. 相似文献
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The goal of uniform mixture design is to scatter the design points in the experimental region uniformly. The commonly used criteria, such as mean square distance, are based on the Euclidean distance. Based on the Lee distance, a new criterion is proposed in this article. And an algorithm, called NTLBG, is also proposed to refine the randomly generated design for the experimental design with mixtures. Some examples show that the design generated by the NTLBG algorithm has a lower criteria value. 相似文献
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In this paper, we are concerned with a test for the index parameter and index function in the single-index model. Based on the estimates obtained by the quantile regression, we extend the generalized analysis-of-variance-type test to the single-index model. We investigate the asymptotic behavior of the proposed test and demonstrate that its limiting null distribution follows an asymptotically χ2-distribution. The simulation studies and real data applications are conducted to illustrate the finite sample performance of the proposed methods. 相似文献
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In many situations the diagnostic decision is not limited to a binary choice. Binary statistical tools such as receiver operating characteristic (ROC) curve and area under the ROC curve (AUC) need to be expanded to address three-category classification problem. Previous authors have suggest various ways to model the extension of AUC but not the ROC surface. Only simple parametric approaches are proposed for modeling the ROC measure under the assumption that test results all follow normal distributions. We study the estimation methods of three-dimensional ROC surfaces with nonparametric and semiparametric estimators. Asymptotical results are provided as a basis for statistical inference. Simulation studies are performed to assess the validity of our proposed methods in finite samples. We consider an Alzheimer's disease example from a clinical study in the US as an illustration. The nonparametric and semiparametric modelling approaches for the three way ROC analysis can be readily generalized to diagnostic problems with more than three classes. 相似文献