Defining the linear portion of a sigmoid‐shaped curve: bend points

Formulae are provided that define the ‘bend points’, the beginning and end of the essentially linear dose–response region, for the four‐parameter logistic model. The formulae are expressed in both response and dose units. The derivation of the formulae is shown in order to illustrate the general nature of the methodology. Examples are given that describe how the formulae may be used while planning and conducting bioassays. Copyright © 2003 John Wiley & Sons, Ltd.     

Four‐Month‐Olds' Discrimination of Voice Changes in Multimodal Displays as a Function of Discrimination Protocol

Past studies have found equivocal support for the ability of young infants to discriminate infant‐directed (ID) speech information in the presence of auditory‐only versus auditory + visual displays (faces + voices). Generally, younger infants appear to have more difficulty discriminating a change in the vocal properties of ID speech when they are accompanied by faces. Forty 4‐month‐old infants were tested using either an infant‐controlled habituation procedure (Experiment 1) or a fixed‐trial habituation procedure (Experiment 2). The prediction was that the infant‐controlled habituation procedure would be a more sensitive measure of infant attention to complex displays. The results indicated that 4‐month‐old infants discriminated voice changes in dynamic face + voice displays depending on the order in which they were viewed during the infant‐controlled habituation procedure. In contrast, no evidence of discrimination was found in the fixed‐trial procedure. The findings suggest that the selection of experimental methodology plays a significant role in the empirical observations of infant perceptual abilities.     

A Numerical Solution to the Nonhomogeneous Two-Stage MVK Model of Cancer

In this article, we describe a straightforward method for solving the probability of at least one malignant cell by time t, and the associated hazard function, in the general (i.e., nonhomogeneous) two-stage Moolgavkar-Venzon-Knudson (MVK) model of cancer. The method consists of solving four coupled ordinary differential equations derived from the Kolmogorov backward equations for this process. The relationship of this method to previously proposed solutions is discussed.     

A sea change on the island continent: frameworks for risk assessment,prevention and intervention in child health in Australia

This article overviews prevention and early intervention approaches focusing specifically on their relevance to the health of children and young people in Australia. Australian public health has a sound track record although concealed within the aggregate profile are a number of sub-populations with poorer health indicators. Recognition of this has increased efforts to improve the health of children and young people especially in exploring the impact of social environments within the communities where children are raised. This paper examines emerging research in this area drawing out key lessons and learning from Australian experience in the field of early intervention and prevention in community settings.     

Joint impact of multiple observations on a subset of variables in multiple linear regression

In multiple linear regression analysis, each observation affects the fitted regression equation differently and has varying influences on the regression coefficients of the different variables. Chatterjee & Hadi (1988) have proposed some measures such as DSSE_ij (Impact on Residual Sum of Squares of simultaneously omitting the ith observation and the jth variable), F_j (Partial F-test for the jth variable) and F_j(i) (Partial F-test for the jth variable omitting the ith observation) to show the joint impact and the interrelationship that exists among a variable and an observation. In this paper we have proposed more extended form of those measures DSSE_IJ, F_J and F_J(I) to deal with the interrelationships that exist among the multiple observations and a subset of variables by monitoring the effects of the simultaneous omission of multiple variables and multiple observations.     

Alternative institutional responses to asbestos

The level of asbestos risk varies widely, with insulation workers facing risks many orders of magnitude greater than other groups, such as school children. After a period of regulatory neglect, asbestos risks are now among the mos stringently regulated risks, with costs per case of cancer prevented on the order of $100 million. Asbestos litigation triggered much of the public action against asbestos, as asbestos cases constituted the majority of all product liability cases in the federal courts from 1988 to 1991. The litigation costs have, however, been substantial, almost three times as great as the amounts transferred to asbestos disease victims. Risk communication potentially could promote efficient risk levels and victim compensation.     

The Ecology of Family Guidance in Low-Income Mexican-American and European-American Families*

This two-part study applied an ecocultural perspective to socialization of daily and long-term goals in low-income Mexican-American and European-American families with children in third, fifth, and seventh grades. The first part of the study examined family members' participation and parents' socialization goals and guidance strategies for their children's daily household chores and homework activities. The second part of the study examined parents' long-term aspirations and guidance strategies for their children's educational, vocational, and moral development. For daily activities, results showed that in Mexican-American families both parents and siblings played important roles, whereas in European-American families parents were the primary socialization agents. As predicted, in both groups parents' expertise influenced their guidance strategies. Finally, Mexican-American and European-American parents differed in their relative endorsement of gender, relational, and self-reliance goals for household chores. For long-term goals, parents in both groups held high educational, vocational, and moral aspirations for their children. However, some parents of seventh-graders had lower educational and vocational aspirations than those of fifth- and third-graders. Although expertise consistently influenced Mexican-American parents' guidance strategies, the pattern for European-American parents was mixed. The discussion highlights between- and within-group differences in daily and long-term socialization practices with an emphasis on resources and vulnerabilities in the families.     

I'm Telling! The Content, Context, and Consequences of Children's Tattling on their Siblings

Tattling on siblings was observed in 40 families with 2- and 4-year-old children. All but 5 children reported sibling misbehaviour to parents with younger siblings tattling largely to recruit parental help in resolving conflict issues, and older siblings tattling both in the context of conflict and merely to inform parents of their siblings' misbehaviour. Parents rarely reprimanded children for tattling, but either ignored it, or responded to information in tattlers' reports regardless of context or whether older or younger children tattled. Children did not tattle equally on all sibling transgressions, but emphasized physical aggression and property damage, issues that also elicited parental discipline. Tattling is discussed in relation to children's understanding of the dynamics and moral standards of family life.     

Married women's retirement behavior

In this paper we examine the economic and family determinants of married women's retirement behavior. A life cycle model of wives' retirement decisions is tested empirically using data on working married women from the Longitudinal Retirement History Survey. This exploratory analysis indicates that family considerations are more important in wives' retirement decisions than own economic opportunities. These findings contrast with those obtained previously for male workers and if substantiated by other research could have important implications for policy questions regarding pension and Social Security reform.This research was funded by the 1986–7 Small Grants Program sponsored by the University of Wisconsin, Madison, Institute for Research on Poverty, the Cornell Institute of Social and Economic Research, and the New York State School of Industrial and Labor Relations. Excellent programming assistance was provided by Vivian Fields. We are grateful to Glen Cain and two anonymous referees for useful comments. Any opinions expressed herein are those of the authors and not those of the above-named persons or institutions.