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931.
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933.
Three experiments were conducted to examine whether the temporal dynamics of Duchenne-smiles influenced the perception of smile authenticity. Realistic computer-generated Duchenne-smiles that varied in their onset- and offset-durations (Experiment 1), or only in their offset-duration (Experiment 2), or in both their onset- and apex-durations (Experiment 3), were created using Poser 4 software. Perceived genuineness varied monotonically with the duration of each manipulated dynamic component. The results are in accordance with Ekman and Friesens (1982) observations regarding the duration of smiles of enjoyment, which suggest that each dynamic component has a distinct duration range that can influence the perceived genuineness of smiles.We wish to thank Jesse Spencer-Smith for sharing the AU morph targets that have been developed in the context of his research. 相似文献
934.
A meta-analysis of college students' physical activity behaviors 总被引:1,自引:0,他引:1
Keating XD Guan J Piñero JC Bridges DM 《Journal of American college health : J of ACH》2005,54(2):116-125
The authors reviewed studies on college students' physical activity (PA) behaviors and found that previous research on this topic focused on describing college students' PA patterns and their determinants. Researchers reported that about 40% to 50% of college students are physically inactive. More important, health and PA professionals in higher education have not been able to effectively increase students' PA behaviors. Interventions to promote students' PA are still at an early stage and have only produced moderate effects. The authors found primary problems with the current research on this topic to be 3-fold: (1) college students' PA has been seriously neglected as a research topic, (2) there is a lack of multiple-level approaches (ie, personal, psychosocial, and environmental levels) for examining PA behaviors in the college student population, and (3) measures of PA are subjective and inconsistent, which makes comparisons of PA patterns among different samples very difficult or impossible. 相似文献
935.
A Distribution for Multivariate Frailty Based on the Compound Poisson Distribution with Random Scale
Frailty models are often used to model heterogeneity in survival analysis. The most common frailty model has an individual intensity which is a product of a random factor and a basic intensity common to all individuals. This paper uses the compound Poisson distribution as the random factor. It allows some individuals to be non-susceptible, which can be useful in many settings. In some diseases, one may suppose that a number of families have an increased susceptibility due to genetic circumstances. Then, it is logical to use a frailty model where the individuals within each family have some shared factor, while individuals between families have different factors. This can be attained by randomizing the Poisson parameter in the compound Poisson distribution. To our knowledge, this is a new distribution. The power variance function distributions are used for the Poisson parameter. The subsequent appearing distributions are studied in some detail, both regarding appearance and various statistical properties. An application to infant mortality data from the Medical Birth Registry of Norway is included, where the model is compared to more traditional shared frailty models. 相似文献
936.
The new generation of psychopharmacological products have proved their efficacy. Some neuro-degenerative diseases, such as Parkinsons and Alzheimers diseases, could be treated by means of the gene therapy. Although the aetiology of such diseases is still not completely known, it has been proven that the patients lack some substances that could be produced by means of the transfer of in vivo or ex vivo genes that codify them in the proper places of the brain. Furthermore, it is announced that the implantation in laboratory grown stem cells of diverse origins is very hopeful. Cerebral (micro)electronic implants could be effective to fight some motor diseases as well as sensory functions. All of these kinds of new treatments need to be tested through clinical research. Most national legislation includes provisions on the clinical trials of drugs and a series of guarantees, procedures and conditions which are designed to ensure protection for individuals used in experiments and to assure that the trial is indeed of scientific relevance. However, few lay down similar regulations or provide for specific controls for the research of other treatments. Finally, enhancement of psychic capacities pose new problems for society as well as do the need for new legal decisions.
相似文献
Zusammenfassung Eine neue Generation psychopharmakologischer Produkte hat ihre Wirksamkeit bewiesen. Manche neurodegenerative Krankheiten, zum Beispiel Parkinson und Alzheimer, konnten mit gentherapeutischen Methoden behandelt werden. Obgleich die Äthiologie solcher Krankheiten noch nicht ganz bekannt ist, konnte gezeigt werden, dass die betroffenen Patienten einen Mangel an bestimmten Substanzen aufweisen, der durch den Transfer von in vivo oder ex vivo Genen, in denen diese Substanzen kodiert sind, an die entsprechenden Stellen im Gehirn behoben werden kann. Außerdem setzt man inzwischen große Hoffnungen auf die Implantation der im Laboratorium kultivierten Stammzellen verschiedenen Ursprungs. Mit (mikro-)elektronischen Gehirnimplantaten könnten bald verschiedene motorische und sensorische Erkrankungen wirksam bekämpft werden. Bevor sie zur Anwendung kommen können, müssen all diese verschiedenen neuen Behandlungsmethoden einer klinischen Erprobung und klinischer Forschung unterzogen werden. In den meisten Ländern sind Gesetze in Kraft, die Bestimmungen hinsichtlich der klinischen Erprobung von Medikamenten enthalten und eine Reihe von Garantien, Prozeduren und Bedingungen vorsehen, die für die Sicherheit von Individuen sorgen sollen, die für solche Experimente herangezogen werden. Außerdem sollen diese Bestimmungen sicherstellen, dass die Versuche auch wissenschaftlich sinnvoll sind. Für die Erforschung anderer Behandlungsarten gibt es dagegen nur wenige gesetzliche Richtlinien, die eine ähnliche Regulation oder spezifische Kontrollmechanismen hinsichtlich der Erforschung dieser Behandlungsmethoden gewährleisten könnten. In diesem Zusammenhang stellen auch Maßnahmen zur Erhöhung psychischer Fähigkeiten die Gesellschaft vor neue Probleme und machen neue gesetzgeberische Entscheidungen notwendig.
Résumé La nouvelle génération de produits psychopharmaceutiques a fait la preuve de son efficacité. Certaines maladies neurodégénératives, comme les maladies de Parkinson et dAlzheimer, ont pu être traitées au moyen de la thérapie génique. Bien que létiologie de telles maladies ne soit pas encore complètement connue, on a démontré quil manque aux patients certaines substances qui pourraient être produites par le transfert in vivo ou ex vivo de gènes qui les codifient au bon endroit dans le cerveau. En outre, on annonce comme très prometteuse limplantation de cellules souches de diverses origines cultivées en laboratoire. Les implants cérébraux (micro-)électroniques pourraient savérer efficace pour lutter contre certaines affections motrices et des fonctions sensorielles. Tous ces types de nouveaux traitements doivent au préalable être testés par la recherche clinique. La plupart des législations nationales prévoient des clauses sur les essais cliniques de médicaments et mettent en place une série de garanties, de procédures et de conditions visant à assurer la protection des individus participant aux essais, et à veiller à ce que les essais ont effectivement une pertinence scientifique. Cependant, leurs réglementations sont rarement similaires et elles ne prévoient en général pas de contrôles spécifiques sur la recherche dautres traitements. Enfin, lamélioration des capacités psychiques pose de nouveaux problèmes pour la société, au même titre que le besoin en nouvelles décisions législatives.
Carlos María Romeo-CasabonaEmail: Phone: +34-944-455793 |
937.
938.
Microfinance Institutions (MFIs) are special financial institutions. They have both a social nature and a for-profit nature. Their performance has been traditionally measured by means of financial ratios. The paper goes beyond simple financial ratios using a data envelopment analysis (DEA) approach to measure the efficiency of MFIs. 相似文献
939.
Women and mediaWomen in the past decades established themselves like in all public fields also in the field of journalisme and media, including leading positions. The larger presence of women as editors, however, not visibly changed the reporting regarding gender-democratic aspects. We cannot state that traditional role assignments were lastingly overcome. With supervision and coaching of media professionals there seems to be a need of a very specific consulting for women. A need of consultation, which might still require a deeper and a more realistic view of the world, a changed perspective regarding women and men in the society. This does not happen automatically, on instruction or by political correctness. To develop this changed perspective and represent it in public, is obviously not easier to women than to men. A way to learn it would be to conceive journalistic and editorial quality under the criterion of gender democracy and diversity. 相似文献
940.
Christian Dudel María Andrée López Gómez Mikko Myrskylä 《Revue europeenne de demographie》2018,34(5):769-791
While there has been considerable debate about extending the length of working life, relatively little is known about this issue. We use data from the Spanish Continuous Working Life Sample for 2004–2013 to calculate period working life tables, which in turn allows us to assess the impact of the financial crisis on working life expectancy in Spain. Before the recession hit, working life expectancy in Spain was around 38 years for males and 33 years for females. The recession had a tremendous impact on the Spanish labor market, but the effects differed considerably by gender and occupational category. Men working in skilled non-manual jobs were less affected, while men working in unskilled manual jobs lost close to 14 years of working life expectancy. Women were less affected than men. With working life expectancy decreasing, the average proportion of lifetime spent in unemployment and outside the labor market increased markedly, whereas the average number of years spent in retirement changed only a little. When we decompose losses in working life expectancy by age group, we find that economic fluctuations affect both older and younger workers. This result suggests that policies that focus on retirement ages only are incomplete. We also compare our findings to the results obtained by Sullivans method, which is based on prevalence rates rather than the incidence-based working life table approach. We find that the use of Sullivans approach does not accurately reflect the levels of and the trends in working life expectancy. 相似文献