The use of population‐level data to advance interdisciplinary methodology: a cell‐through‐society sampling framework for child development research

The authors argue that population‐level data should be used to advance interdisciplinary research about community effects on early development. These data permit the identification of neighborhoods in which development patterns deviate from predictions based on local socioeconomic status (SES). So‐called ‘off‐diagonal’ places signal where researchers are likely to discover processes that either deflect the risks of low SES or dampen the salutary impact of favorable SES. Since such neighborhoods will be best understood relative to nearby ‘on‐diagonal’ neighborhoods where macro‐economic and/or public policy factors are constant, the authors present a methodology for illuminating these regional clusters. The method is deployed in British Columbia, Canada, where a team has collected developmental observations from two censuses of kindergarten children (n = 82,632). The article discusses how these clusters can be used to coordinate sampling decisions among academics representing the range of disciplines needed to study child development from cell‐through‐society, as is recommended in the literature.     

The current state of Bayesian methods in nonclinical pharmaceutical statistics: Survey results and recommendations from the DIA/ASA-BIOP Nonclinical Bayesian Working Group

The use of Bayesian methods to support pharmaceutical product development has grown in recent years. In clinical statistics, the drive to provide faster access for patients to medical treatments has led to a heightened focus by industry and regulatory authorities on innovative clinical trial designs, including those that apply Bayesian methods. In nonclinical statistics, Bayesian applications have also made advances. However, they have been embraced far more slowly in the nonclinical area than in the clinical counterpart. In this article, we explore some of the reasons for this slower rate of adoption. We also present the results of a survey conducted for the purpose of understanding the current state of Bayesian application in nonclinical areas and for identifying areas of priority for the DIA/ASA-BIOP Nonclinical Bayesian Working Group. The survey explored current usage, hurdles, perceptions, and training needs for Bayesian methods among nonclinical statisticians. Based on the survey results, a set of recommendations is provided to help guide the future advancement of Bayesian applications in nonclinical pharmaceutical statistics.     

Revised GRASP with path-relinking for the linear ordering problem

The linear ordering problem (LOP) is an NP\mathcal{NP}-hard combinatorial optimization problem with a wide range of applications in economics, archaeology, the social sciences, scheduling, and biology. It has, however, drawn little attention compared to other closely related problems such as the quadratic assignment problem and the traveling salesman problem. Due to its computational complexity, it is essential in practice to develop solution approaches to rapidly search for solution of high-quality. In this paper we propose a new algorithm based on a greedy randomized adaptive search procedure (GRASP) to efficiently solve the LOP. The algorithm is integrated with a Path-Relinking (PR) procedure and a new local search scheme. We tested our implementation on the set of 49 real-world instances of input-output tables (LOLIB instances) proposed in Reinelt (Linear ordering library (LOLIB) 2002). In addition, we tested a set of 30 large randomly-generated instances proposed in Mitchell (Computational experience with an interior point cutting plane algorithm, Tech. rep., Mathematical Sciences, Rensellaer Polytechnic Institute, Troy, NY 12180-3590, USA 1997). Most of the LOLIB instances were solved to optimality within 0.87 seconds on average. The average gap for the randomly-generated instances was 0.0173% with an average running time of 21.98 seconds. The results indicate the efficiency and high-quality of the proposed heuristic procedure.     

The Impact of Rainfall on the First Out-Migration: A Multi-level Event-History Analysis in Burkina Faso

Using event history analyses, we investigate the impact of rainfall conditions — a crucial environmental factor in the livelihood of Sahelian households— on the risk of the first village departure in Burkina Faso. The distinction of migrations by destination and duration proves critical in studying this relationship. Findings suggest that people from the drier regions are more likely than those from wetter areas to engage in both temporary and permanent migrations to other rural areas. Also, short-term rainfall deficits tend to increase the risk of long-term migration to rural areas and decrease the risk of short-term moves to distant destinations.     

Does Weighting Capture What’s Important? Revisiting Subjective Importance Weighting with a Quality of Life Measure

The present study evaluated subjective importance weighting using data collected with the Injection Drug User Quality of Life Scale (IDUQOL). Weighted and unweighted IDUQOL scores from 241 adults were correlated with convergent, discriminant, and criterion measures. Regression analysis was used to examine the contribution of importance ratings to scores on a global measure of life satisfaction and the corrected weighted IDUQOL total scores. Overall, the results showed that weighted scores did not perform better than unweighted scores in measuring quality of life. However, the mean satisfaction ratings for important domains correlated significantly higher with convergent measures than did the mean satisfaction ratings for unimportant domains. This finding suggests further attention needs to be paid to the meaning and measurement of subjective importance and how it may be incorporated more effectively into measures of quality of life.     

Contents of Volume 68

Volume Contents

Contents of Volume 68     

Effects of international student exchange on pre-service teachers: a quasi-experimental study

This contribution provides empirical answers to the question of how teaching-specific competencies develop during participation in an international student exchange programme. The quantitative analyses of this quasi-experimental study suggest that, generally speaking, no specific developments occur during an exchange experience. These findings contradict the majority of existing literature. Possible reasons for this divergence are discussed. The interpretation of the results suggests future research should focus on the key question of pre-conditions for productive exchange experiences.     

‘The whole is always smaller than its parts’ – a digital test of Gabriel Tardes' monads

In this paper we argue that the new availability of digital data sets allows one to revisit Gabriel Tarde's (1843–1904) social theory that entirely dispensed with using notions such as individual or society. Our argument is that when it was impossible, cumbersome or simply slow to assemble and to navigate through the masses of information on particular items, it made sense to treat data about social connections by defining two levels: one for the element, the other for the aggregates. But once we have the experience of following individuals through their connections (which is often the case with profiles) it might be more rewarding to begin navigating datasets without making the distinction between the level of individual component and that of aggregated structure. It becomes possible to give some credibility to Tarde's strange notion of ‘monads’. We claim that it is just this sort of navigational practice that is now made possible by digitally available databases and that such a practice could modify social theory if we could visualize this new type of exploration in a coherent way.     

Chronic pain,pain severity and analgesia use in Australian women of reproductive age

Background

The increasing prevalence and adverse outcomes associated with opioid analgesia use in women of reproductive age have become a significant public health issue internationally, with use during pregnancy potentially affecting maternal and infant health outcomes.