Modelling human immunodeficiency virus ribonucleic acid levels with finite mixtures for censored longitudinal data

The measurement of human immunodeficiency virus ribonucleic acid levels over time leads to censored longitudinal data. Suitable models for dynamic modelling of these levels need to take this data characteristic into account. If groups of patients with different developments of the levels over time are suspected the model class of finite mixtures of mixed effects models with censored data is required. We describe the model specification and derive the estimation with a suitable expectation-maximization algorithm. We propose a convenient implementation using closed form formulae for the expected mean and variance of the truncated multivariate distribution. Only efficient evaluation of the cumulative multivariate normal distribution function is required. Model selection as well as methods for inference are discussed. The application is demonstrated on the clinical trial ACTG 315 data.     

The Slaughtered and the Survivors: Collaboration Between Social Economy Organizations as a Key to Success in Times of Financial Crisis

The objective of this study is to analyze the aspects that allowed a critical part of Social Economy Organizations (SEOs) to survive a recession period, especially participation in collaborative networks. The financial stress of an SEO will depend on the resources and capabilities available to the organization. To analyze the financial stress of Spanish SEOs, we defined a sample of 714 SEOs. Approximately half of these organizations suffered from financial stress in the analyzed period (2009–2012). The results obtained in this study reveal the existence of three factors that distinguish organizations under financial stress: (a) a high dependence on government funding; (b) changes in the relationship between staff and volunteers; and (c) a lack of access to markets. The combination of these three elements results in an unsustainable situation for the organization. The development of a collaborative profile increases the SEO’s probability of surviving the adverse manifestations of its environment.     

Immigrant Occupational Mobility: Longitudinal Evidence from Spain

This article examines the occupational mobility of immigrants between their countries of origin and Spain on the basis of one of the few surveys available internationally with longitudinal information on immigrant employment in home and host countries. The evidence shows that the occupational status of immigrants in the Spanish labour market is, in general, substantially worse than in their countries of origin. The severe loss of occupational status experienced by immigrants is explained by the combined effect of the intense initial downgrading they experience when entering the Spanish labour market and their very slow occupational progress during their stay in Spain. These findings are more in line with the segmented assimilation theory, which suggests a limited or blocked immigrant occupational mobility, than with the assimilation theory, which predicts a U shaped evolution in the occupational status of immigrants between their home and host countries. As a result, the Spanish case contrasts sharply with previous evidence for other advanced countries, which tends to support the assimilation perspective. Finally, the empirical evidence suggests that one of the elements impeding the occupational mobility of immigrants in Spain is the significant size of the secondary segment of the labour market, which restricts immigrants’ opportunities mainly to low-status occupations.     

Work as a cure for mental illnesses? Opportunism and seeking ways in psychology and psychiatry in the first decades of state socialism in Hungary

ABSTRACT

In Hungary, until the end of the 1940s, there were two main established methods of occupying the mentally ill who were fit for work. From the end of the nineteenth century, a lesser number of patients underwent work therapy in mental asylums, whereas the others were treated with so-called family therapy (otherwise known as the heterofamilial system), exploiting the capacities of families in the countryside. As an important part of this, the mentally ill helped in housekeeping and agricultural work. However, following the political and ideological turn of 1948, the latter form of treatment became debated, and then it was gradually superseded. Parallel to this process, work therapy came to be the most popular type of treatment for mental illnesses, as work formed the basis of the ideology of the communist state, and thus, healing through work harmonized with the general tendencies of the era. This article examines texts related to work therapy published in neurological–psychiatric and psychological journals and monographs between 1954 and 1964. However, although work therapy appeared to be the “handmaiden of ideology,” and even though it was supposed to fulfil a particular role, in reality, the role and perception of work therapy were a lot more complicated.     

Effects of the social dominance orientation on environmental attitudes of Chilean university students / Efectos de la orientación a la dominancia social sobre las actitudes ambientales de universitarios chilenos

By adopting a multidimensional approach to environmental attitudes (apathy, anthropocentrism, connectedness and emotional affinity with nature), this study explores the relationships between these dimensions, social dominance orientation (SDO) and political orientation. Two hundred and sixty-two Chilean university students filled out an ad hoc online questionnaire. Two confirmatory factorial analyses showed the four typologies of environmental attitudes and the two factors for SDO, which are labelled group dominance and opposition to equality. Through hierarchical regressions, group dominance showed higher explanatory power of environmental attitudes than political orientation. Furthermore, using the bootstrap procedure we showed that group dominance mediated between political orientation and attitudes of apathy, anthropocentrism and connectedness, while opposition to equality mediated between apathy and emotional affinity. We conclude that SDO is an important variable for measuring political ideology while also providing new nuances when analysing the relationships with environmental attitudes.     

Measuring operational excellence: an operational excellence profitability (OEP) approach

The pursuit of operational excellence in the manufacturing industry is at rise but its measurement still lacks of appropriate indicators to determine its financial benefits. The ambiguity is due to the impact arisen from manufacturing fluctuations such as price and cost, production mix and direct and indirect parameters variations. Manufacturing fluctuations distort the cost benefit of operational excellence. This paper, therefore, proposes the OEP (Operational Excellence Profitability) indicators to isolate the impact of manufacturing fluctuation and distinctly identify the payback of operational excellence strategies and initiatives through cost benefits of achieving higher efficiency and yield. The paper presents the conceptual and mathematical development of the proposed OEP indicators and the formulas used for their calculation. Hypothetical and industrial-based investigations and applications of the OEP indicators are conducted for their validation. The results obtained from the hypothetical exercise and industrial case suggest that OEP indicators can provide an effective cost-benefit analysis of operational excellence. This would contribute in providing manufacturing organizations with more complete information regarding the performance of their processes, which will allow their directors and managers to take better decisions related to the management and improvement of their processes.     

Social Entrepreneur: Same or Different from the Rest?

VOLUNTAS: International Journal of Voluntary and Nonprofit Organizations - A social business responds to social problems usually ignored by institutions, mobilizing resources and generating...