Conditional Generalized Liouville Distributions on the Simplex

Liouville and generalized Liouville distributions on the simplex have been proposed for modeling compositional data and have been shown to be free from the extreme independence structure that characterizes the Dirichlet class. In this article, generalized Liouville distributions are shown to be rich enough to distinguish some lesser modes of independence as well. Unfortunately, it is noted that the applicability of the Liouville family will be limited, owing to the lack of invariance with respect to the chosen fill-up value. As an alternative, a new family of simplex distributions is proposed, one that admits invariance with respect to choice of fill-up value, as well as the ability to differentiate among many forms of independence.     

Using regression mixture models with non-normal data: examining an ordered polytomous approach

Mild to moderate skew in errors can substantially impact regression mixture model results; one approach for overcoming this includes transforming the outcome into an ordered categorical variable and using a polytomous regression mixture model. This is effective for retaining differential effects in the population; however, bias in parameter estimates and model fit warrant further examination of this approach at higher levels of skew. The current study used Monte Carlo simulations; 3000 observations were drawn from each of two subpopulations differing in the effect of X on Y. Five hundred simulations were performed in each of the 10 scenarios varying in levels of skew in one or both classes. Model comparison criteria supported the accurate two-class model, preserving the differential effects, while parameter estimates were notably biased. The appropriate number of effects can be captured with this approach but we suggest caution when interpreting the magnitude of the effects.     

A Recursive Formulation of the Old Problem of Obtaining Moments from Cumulants and Vice Versa

It seems difficult to find a formula in the literature that relates moments to cumulants (and vice versa) and is useful in computational work rather than in an algebraic approach. Hence I present four very simple recursive formulas that translate moments to cumulants and vice versa in the univariate and multivariate situations.     

Spatial Cluster Detection for Longitudinal Outcomes Using Administrative Regions

This article proposes a new spatial cluster detection method for longitudinal outcomes that detects neighborhoods and regions with elevated rates of disease while controlling for individual level confounders. The proposed method, CumResPerm, utilizes cumulative geographic residuals through a permutation test to detect potential clusters which are defined as sets of administrative regions, such as a town or group of administrative regions. Previous cluster detection methods are not able to incorporate individual level data including covariate adjustment, while still being able to define potential clusters using informative neighborhood or town boundaries. Often, it is of interest to detect such spatial clusters because individuals residing in a town may have similar environmental exposures or socioeconomic backgrounds due to administrative reasons, such as zoning laws. Therefore, these boundaries can be very informative and more relevant than arbitrary clusters such as the standard circle or square. Application of the CumResPerm method will be illustrated by the Home Allergens and Asthma prospective cohort study analyzing the relationship between area or neighborhood residence and repeated measured outcome, occurrence of wheeze in the last six months, while taking into account mobile locations.     

An experimenter’s view of the application of statistics to cloud-seeding experiments

An experimenter in the field of cloud seeding describes aspects of experiments which he would like statisticians to take into account and suggects Problems which he would like statisficians solve.     

Combinatoric classification of multivariate normal variates

Consider classifying an n × I observation vector as coming from one of two multivariate normal distributions which differ both in mean vectors and covariance matrices. A class of dis-crimination rules based upon n independent univariate discrim-inate functions is developed yielding exact misclassification probabilities when the population parameters are known. An efficient search of this class to select the procedure with minimum expected misclassification is made by employing an algorithm of the implicit enumeration type used in integer programming. The procedure is applied to the classification of male twins as either monozygotic or dizygotic.     

Determining the effects of intraclass correlation on factorial experiments

This paper considers the effects of the presence of eqmi-correlation between observations in a k-way factorial experiment, A technique to provide unbiased F-tests is also constructed.     

Practical bayesian approaches to the analystcs of a 2×2 contingency table with incompletely categorized data

To assess the efficacy of a treatment, patients are administered a pre-test, the treatment, and a post-test (identical to the pre-test). These patients are then categorized according to their outcomes observed on both tests,e.g., (S,S), (S,F), etc. Also, we observe "incomplete" information on the pre-tests' outcomes for some patients and the results of only the post-test being known for thers, A Bayesian framework is fit to the problem and Bayes factors, posterior odds ratios, and utility functions are given to evaluate th e treatment, A method of assessing the prior distribution is specified and a numerical example is worked.