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31.
İlknur Aykurt Karlıbel Seyhan Dülger Meliha Kasapoğlu Aksoy Muhammet Güzelsoy Ali Rıza Türkoğlu Lale Altan 《The aging male》2019,22(2):109-115
Objective: This study aims to investigate the effect of smoking on sexual functions in AS patients.Patients and methods: A total of 67 male AS patients with a median age of 34 years (range: 18–57) reporting sexual activity at least for the past 4 weeks period were included. Patients were divided into smokers (Group 1, n?=?47) and non-smokers (Group 2, n?=?20). Fagerström test for nicotine dependence, smoking history, exhaled carbon monoxide test were recorded for smoking AS patients. Visual analogue scale (VAS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Quality of Life (ASQoL), International Index of Erectile Function (IIEF), Beck Depression Inventory (BDI) were filled for both groups.Results: There was no significant difference between smokers and non-smokers in all evaluation parameters. BASMI scores were significantly lower in the mild dependency subgroup as compared to those with moderate or severe dependency (p?=?.005 and p?=?.007, respectively). Total IIEF score and IIEF categories correlated significantly with BASDAI, BASFI, BASMI, ASQoL, pain, fatigue, and cumulative smoking. BDI showed an inverse correlation with the IIEF score and IIEF category (p?.001 r?=?–0.520, p?.001 r?=?–0.508, respectively).Conclusions: Sexual function in AS patients is associated with the pain, fatigue, disease activity, functional status, quality of life, depression as well as the cumulative exposure to smoking, and that sexual functions tend to decline with increasing degree of cigarette dependency. 相似文献
32.
Many optimisation problems arise in managing the Blood Donation (BD) supply chain. Most of them have been addressed in the literature, while other problems, e.g. donation scheduling, have not been sufficiently addressed so far. However, blood collection from donors may have a disruptive impact on the entire BD supply chain if not properly managed. For example, scheduling donation appointments based on some system metrics may improve the flow of blood units through the BD supply chain and increase the quality of service perceived by donors. In this short communication, we present the donation scheduling problem and highlight the lack of work in the literature that deals with this problem. Then, we analyse the impact of an unbalanced flow of blood units on the BD system and the benefits that may derive from a suitable appointment scheduling. Finally, we propose suggestions for future research in BD collection scheduling that may improve the BD process. 相似文献
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Prior information is often incorporated informally when planning a clinical trial. Here, we present an approach on how to incorporate prior information, such as data from historical clinical trials, into the nuisance parameter–based sample size re‐estimation in a design with an internal pilot study. We focus on trials with continuous endpoints in which the outcome variance is the nuisance parameter. For planning and analyzing the trial, frequentist methods are considered. Moreover, the external information on the variance is summarized by the Bayesian meta‐analytic‐predictive approach. To incorporate external information into the sample size re‐estimation, we propose to update the meta‐analytic‐predictive prior based on the results of the internal pilot study and to re‐estimate the sample size using an estimator from the posterior. By means of a simulation study, we compare the operating characteristics such as power and sample size distribution of the proposed procedure with the traditional sample size re‐estimation approach that uses the pooled variance estimator. The simulation study shows that, if no prior‐data conflict is present, incorporating external information into the sample size re‐estimation improves the operating characteristics compared to the traditional approach. In the case of a prior‐data conflict, that is, when the variance of the ongoing clinical trial is unequal to the prior location, the performance of the traditional sample size re‐estimation procedure is in general superior, even when the prior information is robustified. When considering to include prior information in sample size re‐estimation, the potential gains should be balanced against the risks. 相似文献
35.
Demographic ageing is a challenge for many countries. Even though Turkey has a relatively younger demographic composition, the proportion of the older people (65+) within the population is rapidly increasing. Within this framework, older people are becoming more important clients for both social work students and social workers in Turkey. This study aims to reveal the attitudes of social work students towards older people and determine the various factors that affect their views on older persons. In the scope of the project, Kogan's Attitude Towards Old People Scale was applied to 419 social work undergraduate students at a university located in Central Anatolia. The findings showed that social work students scored a mean of 130.96 and they generally had positive attitudes towards older people. The correlation between year of study, gender and age was not statistically significant. However, having lived mostly in urban areas was positively correlated with the mean Kogan scores and this finding was found to be statistically significant. Exposure to personal contact with older people at both the personal and professional levels was influential in shaping attitudes about the older people. 相似文献
36.
Cord A. Müller 《Journal of applied statistics》2019,46(13):2338-2356
ABSTRACTAcceptance sampling plans offered by ISO 2859-1 are far from optimal under the conditions for statistical verification in modules F and F1 as prescribed by Annex II of the Measuring Instruments Directive (MID) 2014/32/EU, resulting in sample sizes that are larger than necessary. An optimised single-sampling scheme is derived, both for large lots using the binomial distribution and for finite-sized lots using the exact hypergeometric distribution, resulting in smaller sample sizes that are economically more efficient while offering the full statistical protection required by the MID. 相似文献
37.
Xinyun Wu Shengfeng Yan Xin Wan Zhipeng Lü 《Journal of Combinatorial Optimization》2016,32(2):445-468
The routing and wavelength assignment problem (RWA) has shown to be NP-hard if the wavelength continuity constraint and the objective of minimizing the number of wavelengths are considered. This paper introduces a multi-neighborhood based iterated tabu search algorithm (MN-ITS), which consists of three neighborhoods with a unified incremental evaluation method, to solve the min-RWA problem. The proposed MN-ITS algorithm is tested on a set of widely studied real world instances as well as a set of challenging random ones in the literature. Comparison with other reference algorithms shows that the MN-ITS algorithm is able to improve five best upper bounds obtained by other competitive reference algorithms in the literature. This paper also presents an analysis to show the significance of the unified incremental evaluation technique and the combination of multiple neighborhoods. 相似文献
38.
Utz Schäffer Jan-Philipp Lüdtke Diedrich Bremer Matthias Häußler 《Zeitschrift für Betriebswirtschaft》2012,82(1):47-73
This paper investigates the influence of accounting standards on systematic earnings understatement. To isolate the effect
of reporting regulations from those of other institutional drivers of earnings management, Holthausen (2003) proposes analyzing
reporting practices in a country undergoing a transition in accounting standards. We respond to this call by analyzing earnings
management practices of large German-listed companies before and after their transitions from German GAAP to IFRS. Specifically,
we focus on Big Bath behavior following Chief Financial Officer turnovers between 1999 and 2006. Our findings provide evidence
of the effect of accounting standards on the existence of this particular earnings understatement pattern. However, while
we detect Big Bath behavior for our sample of German GAAP firms, we find no such indication for those firms reporting under
IFRS. Controlling for alternative explanations such as self-selection bias does not change our findings. We conclude that
accounting standards seem to have a considerable influence on earnings management behavior, independent of managers’ and auditors’
incentives. 相似文献
39.
This article asks what strategies are available to dominated actors in fields of cultural production. Using archival and biographical materials on Ottoman/Turkish women intellectuals, we show that they effectively used, depending on their social and cultural capital and their past practices, at least four strategies. Apart from the well-theorized strategy of subversion, they could also deploy acquiescence, collaboration, and defiance. These four strategies, we argue, constitute a two-dimensional space defined by loyalty vs. resistance on one hand and the overtness vs. covertness of loyalty or resistance on the other. While much of this space is best understood in terms of reciprocal social exchange, the assumptions of exchange break down in the case of overt resistance, showing that strategy goes beyond negotiation and that the understanding of power as always-already implicated with resistance has limits. 相似文献
40.
Günther Josef Mohr 《Organisationsberatung, Supervision, Coaching》2016,23(4):411-426
In the article results of resilience research are presented and a systemic concept of resilience is derived, which differentiates the term from other models regarding psychic health. The resilience square shows essential factors for resilience. Based on this the idea of resilience is transferred to systems and organizations. The article deepens the resilience approach of Mohr (2016). 相似文献