排序方式: 共有44条查询结果,搜索用时 46 毫秒
11.
Takahiro Hasegawa Saori Misawa Shintaro Nakagawa Shinichi Tanaka Takanori Tanase Hiroyuki Ugai Akira Wakana Yasuhide Yodo Satoru Tsuchiya Hideki Suganami 《Pharmaceutical statistics》2020,19(4):436-453
Many clinical research studies evaluate a time‐to‐event outcome, illustrate survival functions, and conventionally report estimated hazard ratios to express the magnitude of the treatment effect when comparing between groups. However, it may not be straightforward to interpret the hazard ratio clinically and statistically when the proportional hazards assumption is invalid. In some recent papers published in clinical journals, the use of restricted mean survival time (RMST) or τ ‐year mean survival time is discussed as one of the alternative summary measures for the time‐to‐event outcome. The RMST is defined as the expected value of time to event limited to a specific time point corresponding to the area under the survival curve up to the specific time point. This article summarizes the necessary information to conduct statistical analysis using the RMST, including the definition and statistical properties of the RMST, adjusted analysis methods, sample size calculation, information fraction for the RMST difference, and clinical and statistical meaning and interpretation. Additionally, we discuss how to set the specific time point to define the RMST from two main points of view. We also provide developed SAS codes to determine the sample size required to detect an expected RMST difference with appropriate power and reconstruct individual survival data to estimate an RMST reference value from a reported survival curve. 相似文献
12.
Hideki Yoshihara 《Long Range Planning》1977,10(2):41-45
In this article the author examines the four features found in the emerging Japanese multinational enterprises, (1) joint ventures with participation of trading companies, (2) the R & D capabilities, (3) the Japanese style of management, and (4) socio-political reactions in Asian countries. These features provide the Japanese multinational enterprises with both opportunities and challenges for their future development. Proper consideration is given to the comparison with the American multinational enterprises. 相似文献
13.
在伪满洲国的文学研究中,即使有关于个别作家及作品的论述,把历史小说作为一个种类进行论述并不多见.但是在拥有悠久历史文化积蓄的中国,以这种丰富的历史典故为题材的文学作品对于五四以后的新文学也是有力的表现方法.尤其是在严厉的言论统治、不能自由表达的伪满洲国,是有效的欺骗敌人的表达手段.作家们以历史上有名人物及故事为题材,描写异民族支配下的中国人民的苦恼及悲哀.在伪满洲国,历史小说是值得重视的文学题材. 相似文献
14.
Kazuhiko Hashimoto 《Social Choice and Welfare》2008,31(3):457-473
We study the optimal design of an organization in which a team of fallible individuals with heterogeneous abilities collectively
decides whether to accept or reject projects. Conventional wisdom tells us that the opinion of those individuals with better
decision-making abilities should be given a “larger” weight in the decision. We formalize this intuition in a sequential evaluation
process and provide specific ways to characterize the optimal decision weights, as well as demonstrate that the magnitude
of the weights depends on the relative abilities of the decision-makers, as well as where the decision-makers are placed in
the project evaluation sequence. 相似文献
15.
16.
This paper presents an approach for time-series livability assessment using DEA (Data Envelopment Analysis), a mathematical
programming technique for measuring the relative efficiency of DMUs (Decision Making Units) with multiple inputs and multiple
outputs. Regarding each year as a separate DMU in DEA, and replacing the inputs and the outputs with negative and positive
social indicators respectively, we evaluate Japan's livability for the period 1956–1990. Results of the analysis using eight
social indicators identify 20 DEA livable years out of the 35 and find eight best-balanced years. It is concluded that DEA,
which enables non-uniform, multi-dimensional and relative evaluation, can be a valuable analytic tool in quality-of-life research
as well.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
17.
Hideki Nakamura 《Journal of Economic Inequality》2013,11(4):517-533
In this paper, we develop a model characterized by skill-biased technological change and increasing costs of education to investigate income inequality. Irregular workers cannot escape poverty by commencing investment in education because wage inequality between regular and irregular workers widens and the price of education increases with the average level of education. Moreover, if the productivity of elementary education is low relative to that of higher education, middle-income individuals are eventually unable to pursue higher education because the threshold for education expenditure rises with the price of education. Thus, income inequality may widen, even among regular workers. 相似文献
18.
Hideki Nagatsuka N. Balakrishnan 《Journal of Statistical Computation and Simulation》2013,83(9):1629-1647
Lognormal distribution is one of the popular distributions used for modelling positively skewed data, especially those encountered in economic and financial data. In this paper, we propose an efficient method for the estimation of parameters and quantiles of the three-parameter lognormal distribution, which avoids the problem of unbounded likelihood, by using statistics that are invariant to unknown location. Through a Monte Carlo simulation study, we then show that the proposed method performs well compared to other prominent methods in terms of both bias and mean-squared error. Finally, we present two illustrative examples. 相似文献
19.
In this paper, we propose a cure rate survival model by assuming that the number of competing causes of the event of interest follows the Poisson distribution and the time to event has the Birnbaum–Saunders (BS) distribution. We define the Poisson BS distribution and provide two useful representations for its density function which facilitate to obtain some mathematical properties. Two closed-form expressions for the moments of the new distribution are given. We estimate the parameters of the model with cure rate using maximum likelihood. For different parameter settings, sample sizes and censoring percentages, several simulations are performed. We derive the appropriate matrices for assessing local influence on the parameter estimates under different perturbation schemes and present some ways to perform a global influence study. We analyse a real data set from the medical area. 相似文献
20.
Edwin M.M. Ortega Gauss M. Cordeiro Elizabeth M. Hashimoto Kahadawala Cooray 《Journal of applied statistics》2014,41(9):1859-1880
We introduce the log-odd Weibull regression model based on the odd Weibull distribution (Cooray, 2006). We derive some mathematical properties of the log-transformed distribution. The new regression model represents a parametric family of models that includes as sub-models some widely known regression models that can be applied to censored survival data. We employ a frequentist analysis and a parametric bootstrap for the parameters of the proposed model. We derive the appropriate matrices for assessing local influence on the parameter estimates under different perturbation schemes and present some ways to assess global influence. Further, for different parameter settings, sample sizes and censoring percentages, some simulations are performed. In addition, the empirical distribution of some modified residuals are given and compared with the standard normal distribution. These studies suggest that the residual analysis usually performed in normal linear regression models can be extended to a modified deviance residual in the proposed regression model applied to censored data. We define martingale and deviance residuals to check the model assumptions. The extended regression model is very useful for the analysis of real data. 相似文献