Model Uncertainty and Bayesian Model Averaged Benchmark Dose Estimation for Continuous Data

The benchmark dose (BMD) approach has gained acceptance as a valuable risk assessment tool, but risk assessors still face significant challenges associated with selecting an appropriate BMD/BMDL estimate from the results of a set of acceptable dose‐response models. Current approaches do not explicitly address model uncertainty, and there is an existing need to more fully inform health risk assessors in this regard. In this study, a Bayesian model averaging (BMA) BMD estimation method taking model uncertainty into account is proposed as an alternative to current BMD estimation approaches for continuous data. Using the “hybrid” method proposed by Crump, two strategies of BMA, including both “maximum likelihood estimation based” and “Markov Chain Monte Carlo based” methods, are first applied as a demonstration to calculate model averaged BMD estimates from real continuous dose‐response data. The outcomes from the example data sets examined suggest that the BMA BMD estimates have higher reliability than the estimates from the individual models with highest posterior weight in terms of higher BMDL and smaller 90th percentile intervals. In addition, a simulation study is performed to evaluate the accuracy of the BMA BMD estimator. The results from the simulation study recommend that the BMA BMD estimates have smaller bias than the BMDs selected using other criteria. To further validate the BMA method, some technical issues, including the selection of models and the use of bootstrap methods for BMDL derivation, need further investigation over a more extensive, representative set of dose‐response data.     

The Development of Cross-Cultural Talent

正I believe that there are many different elements to an outstanding education today.But the element that may be the most new,the most different from what constituted an outstanding education in the past,is the need to help today’s talents to become cross-cultural talents.     

In search of message design best practices: The Silver Anvil Award winners archive

We investigated specific award-winning public relations efforts to derive best practices that bridge industry practices with academic research and pedagogy. The data for this project were the winning entries for the annual Public Relations Society of America's (PRSA) Silver Anvil Award, which is considered the top award recognizing excellence in public relations. We found, however, that the archive of award winners does not provide sufficiently definitive information about what defines any public relations discourse genre or why any genre as used is “excellent.” This archival research provides us with a key rationale for employing rhetorical, narrative, and linguistic theories prospectively to guide public relations message design and planning, theories which hitherto have been used to judge campaigns post hoc or retrospectively.     

Using the contradiction paradigm to assess ageism

Ageism is an important topic in our society, considering the burgeoning older adult population. Ageism is often measured using explicit questionnaires; however, given the impact of social desirability, implicit measures of ageism have been developed. In this study, the contradiction paradigm, an implicit measure of stereotypes (Lassonde, under review) was used to measure age-related stereotypes in passages describing older adults. Participants read passages with target sentences more slowly when these sentences described behaviors that were inconsistent rather than consistent with age-related stereotypes. Participants also completed a series of self-report questionnaires measuring ageism. Results demonstrated that reading times using the contradiction paradigm were not related to outcomes on the self-report questionnaires. A comparison of the contradiction paradigm to a social desirability scale revealed that it was not vulnerable to social desirability. This confirms the contradiction paradigm's use as an implicit measure of age-related stereotypes. Although there is no clear relation between the contradiction paradigm and popular explicit measures, a next important step would be to determine the point in which implicit knowledge and intentional behavioral responses interact.     

The breakdown and influence properties of outlier rejection-plus-mean procedures

In a recent paper, Hampel (1985) studied the properties of rejection-plus-mean procedures as estimators of a location parameter. He reported that these procedures have low breakdown and high variance. In this article it is pointed out that these results are due to the outliers being rejected in a forwards-stepping manner, and when a more appropriate backwards-stepping approach is used, rejection-plus-mean procedures lead to estimators with high breakdown and high variance. In this article it is pointed out that these results are due to the outliers being rejected in a forwards-stepping manner, and when a more appropriate backwards-stepping approach is used, rejection-plus-mean procedures lead to estimator with high breakdown and redescending theoretical influence function.     

A Telephone Intervention for Substance-Using Adult Male Perpetrators of Intimate Partner Violence

OBJECTIVE: To preliminarily evaluate telephone-delivered motivational enhancement therapy (MET) in motivating unadjudicated and nontreatment seeking intimate partner violence (IPV) perpetrators, who also use substances, to self-refer into treatment. METHOD: 124 adult men were recruited via a multimedia marketing campaign and were randomly assigned to the intervention (MET) or comparison group following a baseline assessment. Participants in the MET condition received a personalized feedback report on their IPV and substance-use behaviors, consequences, and social norms beliefs. RESULTS: Results supported the likely effectiveness of MET in short-term reduction of IPV behavior, increasing motivation for treatment seeking, and changing perceived norms for IPV and substance abuse (SA). CONCLUSIONS: Applications for brief MET interventions to facilitate voluntary treatment entry among substance-using IPV perpetrators are discussed.     

Summer learning programs and student success in the global economy

In the United States and around the rest of the world, there is a renewed focus on ensuring that schools are providing students with the skills necessary to compete in the global economy. High-quality summer learning programs are an ideal vehicle to help students gain content knowledge and develop innovative skills: they provide time for individual exploration and hands-on, experiential opportunities that can instill a lifelong love of learning that carries into the classroom and the workforce.     

The demography of disability and the effects of immigrant history: Older Asians in the United States

Using data from the 2000 U.S. census, we compare the older Asian population with U.S.-born, non-Hispanic whites with respect to three indicators of disability. Insofar as any Asian "advantage" in health vis-a-vis whites exists among the population aged 65 and over, our evidence suggests that it occurs primarily among the U.S.-born segments of this population. We also investigate how differences in disability levels among Asian immigrant groups are influenced by country of birth and by the combined effects of duration of residence in the United States and life cycle stage at entry. These results highlight the diversity of the older Asian population with respect to the ways in which immigration and origin history are linked to disability outcomes. We conclude that in later life, immigrant status confers few disability advantages among the Asian population in the United States.