Bayes shrinkage estimator for consistency assessment of treatment effects in multi-regional clinical trials

The primary objective of a multi-regional clinical trial is to investigate the overall efficacy of the drug across regions and evaluate the possibility of applying the overall trial result to some specific region. A challenge arises when there is not enough regional sample size. We focus on the problem of evaluating applicability of a drug to a specific region of interest under the criterion of preserving a certain proportion of the overall treatment effect in the region. We propose a variant of James-Stein shrinkage estimator in the empirical Bayes context for the region-specific treatment effect. The estimator has the features of accommodating the between-region variation and finiteness correction of bias. We also propose a truncated version of the proposed shrinkage estimator to further protect risk in the presence of extreme value of regional treatment effect. Based on the proposed estimator, we provide the consistency assessment criterion and sample size calculation for the region of interest. Simulations are conducted to demonstrate the performance of the proposed estimators in comparison with some existing methods. A hypothetical example is presented to illustrate the application of the proposed method.     

大学章程在大学法人化治理中的价值向度与法律限度

大学章程通过对举办者、办学者及其他利益相关者的意志与权利进行确认,并对各相关权利主体进行制度性的规约,起到了理性化的价值引导与依法治理的保障作用.在创建中国特色的现代大学制度过程中,大学章程能不能被视作一种法律,在多大范围内多大程度上发挥作用,需要理性地审视.研究以中外比较、历史比较、现实发展的视角探讨了我国大学章程的法律效力及其限度.大学章程需要基于“自主管理”的诉求,以“共治”的方式实现现代大学制度的“法治”化,以期实现大学的本质价值追求.     

基于项目教学的《化工生产工艺组织》课程评价体系的构建

化工生产工艺组织课程改革中,建立符合课程特色的评价体系非常重要。评价客体多样化、评价主体多元化、评价指标定量化使本课程的评价更加具有发展性,课程组在此基础上构建了过程性考核和终结性考核相结合的评价体系,实施效果很好。     

吉林省手风琴音乐创作的调查研究

目前,吉林省手风琴音乐的创作现状并不乐观,进行手风琴音乐创作的老艺人们大都年逾古稀,很多都已离世,只能从老艺人留下的历史资料或艺人们的口述中探寻当年吉林省手风琴音乐创作情况的蛛丝马迹.艺人们从事手风琴音乐创作的出发点除教学需要和个人兴趣之外,重要的一点是传承民族文化.要改善吉林省手风琴音乐创作的现状,一是要思考手风琴表演形式的创新,二是音乐创作素材的挖掘与思考.     

Bayesian estimation of rare sensitive attribute

Randomized response models have been used to estimate a population proportion of a sensitive attribute. A randomized device is typically employed to protect respondent's privacy in a survey. In addition, an unrelated question is asked to improve the statistical efficiency. In this article, we propose Bayesian estimation of rare sensitive attribute using randomized response technique, which includes a rare unrelated attribute. Two cases are considered, the proportion of a rare unrelated attribute is known and unknown. A simulation study is conducted to assess the performance of the models using mean absolute error and coverage probability. The results show that the performance depends on the parameters and is robust to priors.     

基于HHM-RFRM的船舶航行风险评估方法研究

船舶航行风险是由各种风险因素交互作用产生。综合 HHM-RFRM 理论，构建船舶航行多维风险情景危险度测度模型，以风险因素耦合视角探讨船舶航行风险管理问题。在船舶航行多维风险情景危险度测度模型中结合贝叶斯定理，对船舶航行风险情景进行了定性与定量化过滤、评级。最后以大连港某从事商务活动的货船为例，验证了所提出方法的可行性。传统的风险评估方法只能评估单个风险因素对系统的影响，此评估方法克服了这一局限性，为船舶航行风险管理提供新的视角。     

适于DSP的模拟信号调制方式自动识别方法研究

提出一种适用于DSP的基于Bessel插值结构的正交数字下变频方案，可实现已调信号调制方式的自动识别。该方案能够实现提取信号的正交分量和同相分量，并且能够提取出较高精度的信号的基本参数，由此得到的特征参数可以准确地识别出信号的调制模式。最后，通过计算机和DSP仿真，证明了它的可行性。     

中国金融产业发展的就业效应研究

文章基于2004-2015年我国31个省市的面板数据,应用空间计量模型研究了我国金融产业的就业效应.研究结果表明,金融集聚、金融发展规模和金融发展效率对金融业就业增长有显著的正效应,且金融集聚与金融发展规模和效率之间的交互作用能促进金融业就业的增长,但金融集聚与金融发展规模之间的交互作用要强于与金融发展效率之间的作用.     

Knowledge and Skills of Sexual Abuse Prevention: A Study on School-Aged Children in Beijing,China

To examine the level of child sexual abuse prevention knowledge and skills in a sample of school-aged children, a total of 559 children from first to fifth grade were recruited from one primary school in Beijing, China. Participants were asked to finish a questionnaire surveying their knowledge and skills of child sexual abuse prevention. Results showed that accurate rate of knowledge on child sexual abuse prevention were between 44.0% and 80.0%. Percentage of participants having applied the self-protection skills of “saying ‘no,’” “going away,” and “telling adults” properly in hypothetical situations was 57.4%, 28.3%, and 48.3%, respectively. Third-to-fifth graders had a better performance than first-to-second graders, and girls performed better than boys. Findings suggest that Chinese school-aged children are in need of knowledge and skills related to child sexual abuse prevention, and education programs should be developed as soon as possible.     

地下钱庄行为的定性与防控——刑法与经济法互动的视角

地下钱庄并非规范的法律概念，我国对地下钱庄法律价值的判断是基于其组织的非正规性而非其行为的违法性，对地下钱庄行为更多地是借助刑法规制和执法严惩而非制度规范和监管指引。以刑法与经济法互动为视角，对地下钱庄所从事的三类主要业务进行具体分析，对相关法律法规予以细致梳理和客观评价，并结合我国金融生态环境和地下钱庄行为特点提出相应的立法建议和防控对策。提出在治理地下钱庄的过程中应当做到经济法规制在前、刑法惩治在后，监管在前、执法在后，宽严相济、疏堵结合。