Dissemination to research subjects: operationalizing investigator accountability

Recent articles have argued from principles of bioethics for the right of research subjects to receive the results of the studies in which they have participated. We argue that accountability is a powerful tool of meso-level analysis appropriate to reasoning about answerability in research ethics, and that it captures the responsibility of researchers to disseminate study results to research subjects. We offer the following features of the research situation as relevant to the manner of dissemination to study subject, in addition to factors already proposed in the literature (risk and impact on health outcome): (a) features of the research subject in relation to identity, personal investment, disease, and community; (b) characteristics of the research study and field of inquiry in relation to certainty and significance; and (c) relationships among the research subjects and the healthcare workers involved in their care and in the research.     

Examining reports and policies on cognitive enhancement: approaches, rationale, and recommendations

The phenomenon of cognitive enhancement is attracting attention in bioethics literature and beyond, in public policy. In response, three bodies--the British Medical Association (BMA); the Commission de l'éthique de la Science et de la technologie (CEST) du Québec; the American Academy of Neurology (AAN)--have produced reports and guidance on this topic. To gain insights into different public policy approaches, rationales, and recommendations on the topic, we analyzed these reports in depth. We found convergence on the definition (with the exception of the CEST) of cognitive enhancement. However, we noted a lack of critical reflection with respect to the underlying rationale for developing these reports, i.e., that cognitive enhancement practices are rampant and represent major social changes. As it currently stands, cognitive enhancement is constituted in a way that challenges the creation of coherent and effective policy recommendations. However, policy makers should not simply wait for definitional consensus and hope that on balance the benefits turn out to be greater than the risks. Some components of cognitive enhancement could be reduced down to clearly identified policy targets to be further examined. Then, if appropriate, policy should be created that is, amongst other criteria, beneficial to the majority of the population.     

Child custody issues and co‐occurrence of intimate partner violence and child maltreatment: controversies and points of agreement amongst practitioners

The situation of families undergoing separation in a context of co‐occurrence of intimate partner violence (IPV) and child maltreatment raises certain issues related to child custody. The results presented in this paper were collected and analysed within the framework of a qualitative study aiming to identify the principal points of agreement and the main controversies amongst practitioners in several different types of organizations. Focus groups were held with a total of 43 practitioners from six different settings concerned with child custody in cases of co‐occurrence of IPV and child maltreatment. Although they agreed on the importance of ensuring the safety of victims of violence, their views diverged on three points: (1) the importance of preserving the father–child relationship; (2) collaboration between voluntary organizations and semi‐voluntary or legal agencies; and (3) consideration of cultural differences.     

Missing siblings: seeking more adequate social responses

Little is known about the experience of family and friends when a young adult goes missing, less is known about how siblings make sense of the experience. Police assistance to locate the missing person may be sought but there is little recognition of going missing or missingness as a social issue, and there is little or no adequate social response to the needs of those left behind. This paper links knowledge of siblings, loss and grief to an understanding of this phenomenon. It presents the methodology and findings of an exploratory, qualitative study into the experiences of nine adult siblings of long-term missing people in Australia and presents the themes drawn from their accounts. The themes are briefly elaborated using direct quotations from participants in the study and represented in a diagram. The paper seeks to develop greater understanding of the inter-relationship between missingness and other social issues, to give voice to the views of participants and to encourage practitioners to engage more purposefully in work with family and friends affected by this issue. Some implications for social work practice are presented.     

Bayesian palaeoclimate reconstruction

Summary.  We consider the problem of reconstructing prehistoric climates by using fossil data that have been extracted from lake sediment cores. Such reconstructions promise to provide one of the few ways to validate modern models of climate change. A hierarchical Bayesian modelling approach is presented and its use, inversely, is demonstrated in a relatively small but statistically challenging exercise: the reconstruction of prehistoric climate at Glendalough in Ireland from fossil pollen. This computationally intensive method extends current approaches by explicitly modelling uncertainty and reconstructing entire climate histories. The statistical issues that are raised relate to the use of compositional data (pollen) with covariates (climate) which are available at many modern sites but are missing for the fossil data. The compositional data arise as mixtures and the missing covariates have a temporal structure. Novel aspects of the analysis include a spatial process model for compositional data, local modelling of lattice data, the use, as a prior, of a random walk with long-tailed increments, a two-stage implementation of the Markov chain Monte Carlo approach and a fast approximate procedure for cross-validation in inverse problems. We present some details, contrasting its reconstructions with those which have been generated by a method in use in the palaeoclimatology literature. We suggest that the method provides a basis for resolving important challenging issues in palaeoclimate research. We draw attention to several challenging statistical issues that need to be overcome.     

Vocal determinants of first impressions of young children

Audiotapes of the voices of77 preschool children were prepared. Subjects listened to the tapes, and then provided their impressions of the competence, leadership, dominance, warmth, and honesty of the children. Judgments of the voices' babyishness and attractiveness were also obtained. Perceivers reliably discriminated the children's voices along the dimensions of babyishness and attractiveness. Moreover, analyses revealed that the previously documented impact of these characteristics on first impressions of adults extends to impressions of young children. The similarity of the effects of these characteristics on impressions formed about children to those revealed for adults suggests that vocal qualities may have an impact on personality development via a process of self-fulfilling prophecy.     

The Legal Status of Turks in Germany

Turks in Germany constitute the single largest non-national group living in the member states of the European Union. This essay examines the legal dimensions of their entry, residence and integration in Germany during the 1990s up to 2002. The evidence shows that, despite long-term settlement patterns, Turks in Germany have not achieved a high level of formal inclusion. However, recent policy reforms have already gone some way to improving their situation, and the impact of planned reforms should equally ensure that this process continues in the future.     

Bayesian variable selection and regularization for time–frequency surface estimation

Summary.  We describe novel Bayesian models for time–frequency inverse modelling of non-stationary signals. These models are based on the idea of a Gabor regression , in which a time series is represented as a superposition of translated, modulated versions of a window function exhibiting good time–frequency concentration. As a necessary consequence, the resultant set of potential predictors is in general overcomplete—constituting a frame rather than a basis—and hence the resultant models require careful regularization through appropriate choices of variable selection schemes and prior distributions. We introduce prior specifications that are tailored to representative time series, and we develop effective Markov chain Monte Carlo methods for inference. To highlight the potential applications of such methods, we provide examples using two of the most distinctive time–frequency surfaces—speech and music signals—as well as standard test functions from the wavelet regression literature.     

The politics of disability and access: the Sydney 2000 Games experience

The article examines disability and access issues surrounding the Sydney 2000 Olympic and Paralympic Games. Central to this is an examination of the involvement of the Australian community of people with disabilities [1] within the Games. The Sydney Paralympic Games, in particular, was seen as a possible watershed event for developing accessible infrastructure, and raising awareness of disability and access issues. This paper draws on the official documents of the Games, newspaper accounts and disability organisation reports. The article first examines the major bodies charged with organising the Games, and the planning processes used to incorporate disability and access issues. It then examines a range of critical issues and their relationships with the disability community. Finally, the article provides an analysis of any likely legacies that the 2000 Games may have for Sydney's community of people with disabilities.