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The ability of children to use looking behavior as a cue to guide their mentalistic attributions was assessed. In Experiment 1 video displays were presented in which a protagonist faced one of two potential goals, half of the time standing equidistant from both targets and in the remaining trials standing closer to the target not being faced. Preschoolers consistently based their inferences of another's attention and goal on the direction in which the protagonist was facing. However, in Experiments 2 and 3 preschoolers experienced difficulty in correctly inferring an actor's desired goal when the protagonist's body was oriented in a direction opposite of where she was looking. Under these conditions, only young elementary school children consistently inferred that the protagonist's goal was the target being looked at (Experiment 2). The results from these three studies suggest that an important development occurring in childhood is the ability to consistently distinguish gaze from body orientation when inferring the goals of another. The implications of this development for children's understanding of the mind are discussed. 相似文献
73.
There is a great deal of interest in studying the joint action between chemotherapeutic agents, particularly in screening compounds for therapeutic synergism. In this paper, we propose an approach to study therapeutic synergism using logit models when the data are binary. The key is to convert the definition of therapeutic synergism to its equivalence in terms of the model parameters. Thereby, evaluating therapeutic synergism amounts to examining parameter estimates in the most parsimonious model fit to the data. The proposed approach was further applied to an experimental situation where it was desirable to rank several test articles when administered jointly with a common compound in the treatment of shock. 相似文献
74.
Differences between Southern and non-Southern blacks living in the North and West are considered for a wide variety of attributes such as employment, occupation, income, marital stability, and offspring's performance in school. Migrant blacks have generally more favorable rates than their Northern- and Western-born compatriots after standard domographic controls are applied to an unusually detailed set of cross-tabulations based on the One-Percent Sample Tapes for 1960. Perhaps the sharpest gap exists with respect to marital conditions; Southern blacks of both sexes are more likely to marry and, among those ever married, live more frequently with their spouses. Some of the results reported by earlier investigators require considerable modification; For example, the fact that Northern black men are less often at work than migrants has led to speculations about regional differences in work orientation among blacks, but a detailed analysis of labor force activity indicates this pattern does not hold for women. Likewise, the migrant income advantage is found to vary by education such that it is confined to those with low educational attainment. The use of sample tapes permits a novel analysis of differences between Northern-born blacks classified by whether they are second or at least third generation residents of the North (children of Southern- or Northern-born parents, respectively). For the attribute measured, school performance, the gap is essentially nil. Finally, an alternative is suggested to the existing causal interpretations of North-South gaps among black residents of the North. Reconsidered in particular are the higher labor force rates of migrant men and their more frequent employment in blue collar jobs; 相似文献
75.
Assuming a first-order Markov chain, we propose a structural model for the transition probabilities in vote intention. The proposed model utilizes the ordering among the categories representing vote intentions and carries the flavor of distance models. It also allows a stochastic ordering among distributions reflecting the extent of change. The model is easy to fit and provides a nice interpretation of the data. The model is applied to a panel study of vote intention acquired through six successive interviews before the 1940 Presidential election in Erie County, Ohio. 相似文献
76.
This study explored how couples of Mexican origin define power in intimate relationships, what makes men and women feel powerful in relationships, and the role of each partner in decision making about sexual and reproductive matters. Interviews were conducted with each partner of 39 sexually active couples and data were analyzed using content analysis. Results indicate that power is perceived as control over one s partner and the ability to make decisions. Women say they feel more powerful in relationships when they make unilateral decisions and have economic independence. Men feel powerful when they have control over their partner and bring home money. Respondents agreed that women make decisions about household matters and children, while men make decisions related to money. Findings indicate that whereas couples share decision making about sexual activities and contraceptive use, men are seen as initiators of sexual activity and women are more likely to suggest condom use. 相似文献
77.
Catalano MD Campagna M Doner-Galle T Chiappetta KM Neuhaus C Peters S Dale L 《Work (Reading, Mass.)》1999,12(2):189-194
OBJECTIVES: This study examined the validity of hand therapists' self-report of cumulative trauma disorder (CTD) risk factors by comparing the self-report to observations performed by the raters. Inter-rater reliability was also analyzed between the raters who observed the hand therapists. STUDY DESIGN: Two raters simultaneously observed each hand therapist during a splinting task at a therapy facility. Following this task, the raters and the hand therapist independently completed an identical assessment tool. Thirteen therapists were observed and a total of six raters observed the therapists. Responses from two categories of the self-assessment, "posture" and "mechanical stress", were compared. Percentage of agreement was calculated by dividing the number of like responses by the total number of possible responses for each category. RESULTS: Overall inter-rater reliability was 72%, significantly above the accepted minimum standard of 60-70%, and validity was 39%, significantly below the accepted minimum. CONCLUSION: The high percentage of inter-rater reliability established consistency and accuracy among the raters in their observations. However, the low percentage of validity should prompt hand therapists to investigate the accuracy of a patient's self-report before relying on it for treatment. 相似文献
78.
Christine Fletcher Christy Chuang‐Stein Marie‐Ange Paget Carol Reid Neil Hawkins 《Pharmaceutical statistics》2014,13(4):265-274
‘Success’ in drug development is bringing to patients a new medicine that has an acceptable benefit–risk profile and that is also cost‐effective. Cost‐effectiveness means that the incremental clinical benefit is deemed worth paying for by a healthcare system, and it has an important role in enabling manufacturers to obtain new medicines to patients as soon as possible following regulatory approval. Subgroup analyses are increasingly being utilised by decision‐makers in the determination of the cost‐effectiveness of new medicines when making recommendations. This paper highlights the statistical considerations when using subgroup analyses to support cost‐effectiveness for a health technology assessment. The key principles recommended for subgroup analyses supporting clinical effectiveness published by Paget et al. are evaluated with respect to subgroup analyses supporting cost‐effectiveness. A health technology assessment case study is included to highlight the importance of subgroup analyses when incorporated into cost‐effectiveness analyses. In summary, we recommend planning subgroup analyses for cost‐effectiveness analyses early in the drug development process and adhering to good statistical principles when using subgroup analyses in this context. In particular, we consider it important to provide transparency in how subgroups are defined, be able to demonstrate the robustness of the subgroup results and be able to quantify the uncertainty in the subgroup analyses of cost‐effectiveness. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
79.
Urban Ecosystems - Over a third of the world’s crops require insect pollination, and reliance on pollination services for food continues to rise as human populations increase. Furthermore, as... 相似文献
80.