Leg-extension strength and chair-rise performance in elderly women with Parkinson's disease

The lower extremity performance in elderly female patients with mild to moderate Parkinson's disease (PD; n = 12) and controls (n = 16) was compared. Isometric dynamometry and force-plate measurements were used. PD patients had lower (p < .05) bilateral (BL) maximal isometric leg-extension force (MF), BL isometric MF relative to body mass, and maximal rate of isometric force development than control participants. BL strength deficit was greater (p < .05) in PD patients than in controls. A significantly longer chair-rise time and lower maximal rate of vertical-ground-reaction-force development while rising from a chair was found in PD patients than in controls. These findings suggest that elderly women with PD have lowered voluntary isometric force-generation capacity of the leg-extensor muscles. Reduced BL leg-extension strength might contribute to the difficulty of individuals with PD to rise from a chair.     

基于细胞的生物传感器:用石英晶体微天平方法研究膜蛋白相互作用

在药物开发早期选择最优的候选目标物对于避免后期药物研发失败是至关重要的。Attana200细胞生物传感器能检测目标物在生物基质条件下的无标、全实时动力学情况,提供一个信息丰富的生物学相关的测量方法。细胞能在传感器表面生长,和传统传感器一样通过连续流引入相互作用的生物分子。该仪器还兼容标准生物传感器表面,而且可用于比较键合的纯化目标和相互作用的细胞。     

Attachment and leader's development via experiences

Apart from biographies and memoirs of outstanding leaders, studies on the development of leaders in everyday life from childhood to maturity are rare. We propose a developmental model of leaders in which certain variables formed in early childhood are the basic components for leadership development in later life. These are a low level of trait anxiety [Spielberger, C.D. (1972). Conceptual and methodological issues in anxiety research. In C.D. Spielberger (Ed.), Anxiety: Current trends in theory and research. New York: Academic Press, vol. 1] and openness to experiences [Costa, P.T. Jr., & McCrae, R.R. (1992a). Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) professional manual. Odessa, FL: Psychological Assessment Resources]. We argue that secure attachment style [Bowlby, J. (1969). Attachment and loss: Vol. 1. Attachment. New York: Basic Books] explains the formation and influence of these basic components, which in turn affect the leader's development through experience in leadership roles. Questionnaires were administered to 286 subjects. The data obtained were analyzed by structural equation modeling (SEM).The findings show that trait anxiety and openness to experience affect leaders' development via experiences. Alternative models in which formative variables may affect the magnitude and intensity of leadership experiences are discussed.     

Globalisierung und die Veränderung sozialer Ungleichheiten in modernen Gesellschaften

This article deals with the effects of globalization on individual life courses and employment careers and the resulting changes in patterns of social inequality in modern societies. Empirically, we draw back to results from the international research project GLOBALIFE which studied the effects of globalization on modern life courses for the first time. The results show that the effects of globalization on individual life courses show marked differentiation with regards to specific life course phases: while especially the employment of mid-career men remained considerably stable under globalization, the careers of young adults, mid-career women as well as late-career workers underwent significant alterations. At the same time, results from the GLOABLIFE study indicate that the changes induced by globalization have not yet led to identical results at the national level. Globalization appears to be differentially filtered by deeply embedded and path-dependent national institutions. These “institutional packages” entail variable forms of labour market “flexibilisation” which themselves differentially shape patterns of social inequality in modern societies: While Scandinavian countries have largely succeeded in limiting an increase in social inequality under globalization through active public welfare engagement, globalization has led to a significant amplification of social inequalities in other regime types, either between labour market insiders and outsiders (in conservative and Southern European countries) or between individuals with different human capital resources (in liberal countries).     

Deepwater Horizon Oil Spill Exposure,Industry Sector,and Child Health

Population Research and Policy Review - The historic 2010 BP Deepwater Horizon Oil Spill (DHOS) led to public distress regarding potential impacts on children in nearby Gulf Coast communities....     

Perspectives on Social Care Practice in Romania: Supporting the Development of Professional Learning and Practice

This paper examines the authors’ experiences of developingand delivering training for workers in social care servicesin Romania, through a European Union PHARE¹ funded project.The authors use their experiences to draw on the past and currentpractices of those social workers who were participants in thetraining and to explore their understanding of the emergingissues and themes for social work in Romania. There is alsoan exploration of the potential opportunities for the furtherdevelopment of professional social work learning and practicewithin Romania. The case is made that learning and developmentof social workers could be supported through the encouragementof participatory networks and ‘communities of practice’.     

Performance Evaluations as Gender Barriers in Professional Organizations: A Study of Auditing Firms

Gendering processes often take the form of organizational subtexts, that is, seemingly gender‐neutral practices that have gender implications. The purpose of this article is to study performance evaluations, which, based on management by objectives systems, may appear neutral, but tend to be based on male norms of what is regarded as good performance. We analysed the careers and performance evaluations of 391 newly licenced Swedish auditors, using an open‐ended question survey. In this industry 50 per cent of new employees and 92 per cent of partners are men. Even in the early stages of their careers, there are notable differences between women and men. The women achieved less and show lower career ambitions and expectations as well as greater intentions to leave the auditing industry. Performance evaluations are also perceived differently, men focusing on what is evaluated (reflecting the perceptions of those at higher hierarchical levels) and women focusing on who does the evaluating and how.