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Individual participant data meta-analyses (IPD-MAs) have several benefits over standard aggregate data meta-analyses, including the consideration of additional participants, follow-up time, and the joint consideration of study- and participant-level heterogeneity for improved diagnostic and prognostic model development and evaluation. However, IPD-MAs are resource-intensive and require careful budgeting of time from data contributing groups, a dedicated management team, diversity of expertise, clearly documented data sharing and authorship agreements, and consistent and clear communication. We present a toolkit to facilitate the implementation and management of IPD-MAs, from study recruitment to retrospective harmonization. The toolkit was developed and refined over our work on multiple multinational IPD-MA projects over the last 13 years. The toolkit's budget and email templates, agreements, project management spreadsheets, and standard operating procedures are meant to facilitate routine IPD-MA tasks to expedite implementing and managing future IPD-MA projects.  相似文献   
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Pluriactivity in rural Norway   总被引:2,自引:0,他引:2  
This article relates the results of a study carried out on the roles and functions of pluriactivity in rural Norway. The study sought to define the effect on pluriactivity of the integration of rural areas into urban labour markets, international systems of production, and the changes in the sectoral mix in rural areas. The analysis is based on three types of data: a list of enterprises from the national register of economic units, the central register of employed workers, and information from local informants in the sample municipalities. The article concludes that the rate of pluriactivity among the rural population depends on the way in which economic sectors are classified. A further finding is that pluriactivity is an important feature of rural Norway, but is still mainly associated with agricultural enterprise. A final conclusion is that pluriactivity has other characteristics in larger labour markets than in smaller labour markets in rural areas due to the urban influence on the former.  相似文献   
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汇率风险中经济风险被认为是最重要的风险之一。经济风险管理的一个重要途径就是合理地降低和控制经济风险暴露。应根据经济风险暴露的决定因素,采取控制某一种外币的净现金流量规模,将风险分散于多种外币上,控制市场需求对产品价格及汇率的敏感程度、控制企业运营的成本状态、提高企业的风险管理水平等手段和措施,将汇率风险的经济风险暴露控制在合理的水平。  相似文献   
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The authors consider the linear model Yn = ψXn + ?n relating a functional response with explanatory variables. They propose a simple test of the nullity of ψ based on the principal component decomposition. The limiting distribution of their test statistic is chi‐squared, but this distribution is also an excellent approximation in finite samples. The authors illustrate their method using data from terrestrial magnetic observatories.  相似文献   
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医学生就业心理误区及调适   总被引:4,自引:0,他引:4  
完成长达五年的医科学业,进入人才市场求职择业,是大学生们人生的重大转折。面对日益激烈的高校毕业生就业市场,莘莘学子容易走入心理误区,从而影响他们顺利就业。文章在问卷调查的基础上,对医学生的各种就业心理误区及其成因进行了剖析,并提出了帮助医学生走出心理误区的方法。  相似文献   
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In fixed-odds numbers games, the prizes and the odds of winning are known at the time of placement of the wager. Both players and operators are subject to the vagaries of luck in such games. Most game operators limit their liability exposure by imposing a sales limit on the bets received for each bet type, at the risk of losing the rejected bets to the underground operators. This raises a question—how should the game operator set the appropriate sales limit? We argue that the choice of the sales limit is intimately related to the ways players select numbers to bet on in the games. There are ample empirical evidences suggesting that players do not choose all numbers with equal probability, but have a tendency to bet on (small) numbers that are closely related to events around them (e.g., birth dates, addresses, etc.). To the best of our knowledge, this is the first paper to quantify this phenomenon and examine its relation to the classical Benford’s law. We use this connection to develop a choice model, and propose a method to set the appropriate sales limit in these games.  相似文献   
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联系蔡元培对社会问题的基本思考,探讨了蔡元培健全人格教育思想的产生其内涵,分析了蔡元培的美育思想在健全人格形成中的地位和作用,认为美育思想是从道德教育入手改进社会的手段。  相似文献   
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