An assessment of the statistical methods used to analyse toxicology studies

The Statisticians in the Pharmaceutical Industry Toxicology Special Interest Group has collated and compared statistical analysis methods for a number of toxicology study types including general toxicology, genetic toxicology, safety pharmacology and carcinogenicity. In this paper, we present the study design, experimental units and analysis methods.     

Does welfare reform affect fertility? Evidence from the UK

This paper provides evidence on the effect of welfare reform on fertility, focusing on UK reforms in 1999 that increased per-child spending by 50% in real terms. We use a difference-in-differences approach, exploiting the fact that the reforms were targeted at low-income households. The reforms were likely to differentially affect the fertility of women in couples and single women because of the opportunity cost effects of the welfare-to-work element. We find no increase in births among single women, but evidence to support an increase in births (by around 15%) among coupled women.     

School Students at Work

Over half of three hundred fifth-formers surveyed had taken holiday jobs and over a third worked part-time during the school term. The average remuneration for those who worked was $1.75 for boys and $1.20 for girls and the average time in employment per week was almost twenty hours in the holidays and about seven and a half during term. While the respondents reported that they worked for money and to gain acceptance in the adult world, a majority of them stated that they favoured compulsory work experience, advocating that all students should spend time on farms or in factories as part of their education.     

UK Paramedics Confidence in Identifying Child Sexual Abuse: A Mixed-Methods Investigation

United Kingdom (UK) paramedics are in a prime position to identify children and young people who are victims or at risk of sexual abuse. Paramedics have access, by phone, or in person, to unprepared homes and communities which other health professionals such as social workers may not. Little research exists however, investigating UK paramedic confidence in identifying child sexual abuse. This mixed-method explanatory sequential investigation used the self-reported confidence levels of 276 UK paramedics to inform the design of seven semi-structured focus groups with 25 UK paramedics from a large ambulance service with operating models similar to all UK services. Multiple factors contribute to a lack of confidence in identifying child sexual abuse, child sexual exploitation, and female genital mutilation, including a perceived lack of exposure to sexual abuse, the perceived hidden nature of sexual abuse, and the lack of physical symptoms and examination. An overarching lack of knowledge is the most significant contributor to a lack of confidence which in turn perpetuates misinformation surrounding prevalence, location, and the signs and symptoms of sexual abuse. These findings suggest a lack of sufficient training and a need for further research evaluating the content of current training and its method of delivery.     

Bayesian CV@R/super-quantile regression

In this paper we provide a Bayesian interpretation of the conditional value at risk, CV@R, or super-quantile regression recently developed by Rockafellar et al. [Super-quantile regression with applications to buffered reliability, uncertainty quantification, and conditional value-at-risk, Eur. J. Oper. Res. 234 (2014), pp. 140–154]. Computations are based on particle filtering using a special posterior distribution consistent with the super-quantile concept. An empirical application to data used by RRM as well to another data set on energy prices confirms their results and shows the applicability of the new techniques.     

The price of youth: commodification of young people through malleable risk practices

Risk has become a dominant part of theory and practice in young people's services over the past 30 years [Kemshall, H. 2008. “Risk, Rights and Justice: Understanding and Responding to Youth Risk.” Youth Justice 8 (1): 21–37; Goldson, G. 2000. “Children in Need’ or ‘Young Offenders’? Hardening ideology, organizational change and new challenges for social work with children in trouble.” Child and Family Social Work 5 (3): 255–265]. Young people are simultaneously described as ‘at-risk’ and risky, ‘permanent suspects’ [Mcara, L., and S. Mcvie. 2005. “The usual suspects? Street-life, young people and the police.” Criminal Justice 5 (1): 5–36] with the potential for committing crime, using drugs, being sexually promiscuous or under-performing in the socio-economic climate [Turnbull, G., and J. Spence. 2011. “What's at risk? The proliferation of risk across child and youth policy in England.” Journal of Youth Studies 14 (8): 939–959]. This paper reports on a UK study of youth practitioners’ perceptions of young people in relation to ‘risk’ and how this affects practice. Findings identify a context where practitioners engage with notions of young people as at-risk or risky, managing tensions between external constructions and the ‘real’ individual on an on-going basis. ‘Risk’ becomes malleable, with young people's risk biographies being amplified or attenuated on the basis of the practitioner's view of needs, resource allocations, contracts, targets, practitioner or organisational fears, risk management processes, and the desire to get the best for the young person. Whilst of short-term benefit, this commodification of young people is counter-productive, magnifying the construction of youth as risky others. The paper calls for new approaches to challenge the continued dominance of the youth risk paradigm in practice, policy and the academic youth studies field.     

‘Nomadic’ organization and the experience of journeying: Through liminal spaces and organizing places

This paper explores the author's experience of ‘nomadic’ organization [Deleuze, G., and F. Guattari. 1988. A Thousand Plateaus. London: Continuum] through the findings of an ethnographic study of an annual folk-culture community festival in a rural region of Sweden. The study concerned the practices of one small village community organizing group, of which the author was a member, in contributing to the festival. Using autoethnographic methods, the author brings together phenomenological theories of embodied knowledge [Merleau-Ponty, M. 1962. The Phenomenology of Perception. Abingon: Routledge; Küpers, W. 2011. “Dancing on the Līmen – Embodied and Creative Inter-Places as Thresholds of Be(com)ing: Phenomenological Perspectives on Liminality and Transitional Spaces in Organisation and Leadership.” Tamara – Journal for Critical Organization Inquiry Special Issue on Liminality 9 (3–4): 45–59.] and process theories or organizing [Chia, R. 1999. “A Rhizomic Model of Organizational Change and Transformation: Perspective from a Metaphysics of Change.” British Journal of Management 10 (2): 209–227; Tsoukas, H., and R. Chia. 2002. “On Organizational Becoming: Rethinking Organizational Change.” Organization Science 13 (5): 567–582] to examine his experiences of nomadic ‘journeying’. This highlights his movement in and through liminal spaces, both physical and metaphorical, as part of the research project, and his engagement with fellow participants in the co-construction of a place as part of the festival site organization. The impacts of these experiences on the author and their implications for the spatial relations of organizing are examined using fragments of reflexion, incorporating photographic and poetic elements.     

Repositioning Risk and Resilience: Improving the Lives of Children and Adults with Mental Health Problems in Eastern Europe and Central Asia

The repositioning of risk and resilience within the social work and mental health agenda is examined in this paper through a consideration of the social exclusion of vulnerable children and adults living in Eastern Europe and Central Asia (EECA). There is a pressing need in this region for the development of better conceptions and cultural adaptations of risk and resilience models. An important task is spelling out the implications for effective prevention and intervention programs, and for practitioners and service users in terms of an inclusive, person-centred, and emancipatory practice. The societies of the EECA region may be understood as comprising a distinctive form of risk society, distinguished from Western counterparts by their adverse risk levels, and by their emancipatory potential. Strategies based on user inclusion and participatory action require to be fashioned, along with the development of the social work profession, to facilitate the empowerment of users in the EECA region.     

Always Look a Gift Horse in the Mouth: Community Organisations Controlling Assets

The idea of community-based organisations (CBOs) owning or managing physical assets, such as land or buildings, has a long history in many countries. This paper examines policy and practice in the UK where there has been significant interest in this field. A variety of benefits have been attributed to the role of assets including motivating community engagement, providing a vehicle for outsourcing public services, or creating financially sustainable organisations. The empirical research reveals there is a heterogeneous set of CBOs holding assets, but the majority of them are small with few paid staff. The analysis proposes a spectrum of CBO types in the field. It concludes that policy makers will need to recognise that these types are informed by contrasting traditions, ideas and operating logics that affect their different practices and resource dependencies.