Direct and Indirect Causal Effects via Potential Outcomes*

Abstract. The use of the concept of ‘direct’ versus ‘indirect’ causal effects is common, not only in statistics but also in many areas of social and economic sciences. The related terms of ‘biomarkers’ and ‘surrogates’ are common in pharmacological and biomedical sciences. Sometimes this concept is represented by graphical displays of various kinds. The view here is that there is a great deal of imprecise discussion surrounding this topic and, moreover, that the most straightforward way to clarify the situation is by using potential outcomes to define causal effects. In particular, I suggest that the use of principal stratification is key to understanding the meaning of direct and indirect causal effects. A current study of anthrax vaccine will be used to illustrate ideas.     

Rural/Urban Differences in Child Growth and Survival in Bolivia

Abstract Using data from a national survey in Bolivia and from a regional sample of poor communities in two regions of Bolivia, we model the effects of community conditions, household characteristics, and social relations on child health as measured by child mortality and stunted growth. Based on national data, children in rural areas are twice as likely to die before the age of two than are children in large cities, and about one‐third of the children in rural areas are stunted. Including measures of community, household, and maternal characteristics accounts for at least two‐thirds of the urban/rural difference in child health. We conclude that expansion of health services, improvements in household and community sanitation, and socioeco‐nomic development are all needed to overcome the rural disadvantage in child health.     

Transnational Migration: Bringing Gender In

This article aims to bring gender into an even tighter transnational migration focus by broadening and deepening our original framework of “gendered geographies of power,” linking it more directly to existing and emerging scholarship. We examine and highlight previously neglected areas such as the role of the state and the social imaginary in gendering transnational processes and experiences. We identify topics that remain under‐appreciated, under‐researched, and/or under‐theorized. Finally, we initiate a discussion of how a gendered analysis of transnational migration can help bridge this particular research to other gendered transnational processes under study that do not privilege migration.     

A simple procedure for the selection of significant effects

Summary.  Given a large number of test statistics, a small proportion of which represent departures from the relevant null hypothesis, a simple rule is given for choosing those statistics that are indicative of departure. It is based on fitting by moments a mixture model to the set of test statistics and then deriving an estimated likelihood ratio. Simulation suggests that the procedure has good properties when the departure from an overall null hypothesis is not too small.     

魏晋南北朝的美学思想和盆景艺术

魏晋南北朝是中国古代动乱最多、人民生活最悲惨的时代。战争、动乱使汉王朝“独尊儒术”的旧思想体制大崩溃 ,导致魏晋南北朝时期的古代中国思想最解放、最自由。美学思想和精神的自由 ,酿就了艺术创造精神的勃发 ,因而新的艺术形式、艺术规律应运而生并相互融会贯通。此时的盆景艺术正是在绘画、园林、盆栽、赏石等艺术形式的影响下孕育了自己最初的表现形式和美学规律 ,因此可以说该时期是盆景发展史上的一个重要阶段     

THE EFFICACY AND EFFECTIVENESS OF MARITAL AND FAMILY THERAPY: A PERSPECTIVE FROM META-ANALYSIS

This article reviews the major findings from a multiproject meta-analysis of the effects of marital and family therapy (MFT). Across 163 randomized trials, MFT demonstrates moderate, statistically significant, and often clinically significant effects. No orientation is yet demonstrably superior to any other, nor is MFT superior to individual therapy. Cost effectiveness information is scant in these 163 studies, but supportive. Randomized experiments yield very different answers from nonrandomized experimental studies of the effects of MFT, calling into question whether we should mix the two in reviews. We have also found several new differences in the ways that marital therapy (MT) and family therapy (FT) studies are conducted, making them harder to compare. Finally, important questions still exist about whether any psychotherapy, including MFT, yet has sufficient information about how well research generalizes to everyday clinical practice.     

A screening system for tardive dyskinesia: development and implementation.

1. Most diagnosed cases of tardive dyskinesia (TD) are mildly inconvenient to the patient, but some can be severe or life-threatening. The primary goal of intervention should be early identification of abnormal movements related to TD and the prescribing of an appropriate medication regimen. 2. Unless specific training occurs and a specific monitoring system is in place, TD movements may be missed. However, not all movements are necessarily related to TD. 3. Although screening and monitoring are valuable, nothing is more important than prevention. New medications must be developed that do not carry the risk of TD, and other approaches to treat TD must be developed.     

Estimating the Rayleigh distribution scale parameter from doubly censored samples—Some comments

In a recent paper in this journal, Lee, Kapadia and Brock (1980) developed maximum likelihood (ML) methods for estimating the scale parameter of the Rayleigh distribution from doubly censored samples. They reported convergence difficulties in attempting to solve numerically the nonlinear likelihood equation (LE). To mitigate these difficulties, they employed approximations to simplify the LE, but found that the solution of the resulting simplified equation can give rise to parameter estimates of erratic accuracy. We show that the use of approximations to simplify the LE is unnecessary. In fact, under suitable parametric transformation, the log-likelihood function is strictly concave, the ML estimate always exists, is unique and finite. Furthermore, the LE is easy to solve numerically. A numerical example is given to illustrate the computations involved.     

Recurrent pain in college students.

The authors investigated the prevalence of recurrent pain in a college student sample. Of the 1,564 students surveyed, 467 (29%) indicated that they had experienced recurrent pain at an intensity that was mostly in the mild-to-moderate range. Students who reported having recurrent pain were significantly older and more depressed than students who did not indicate they suffered from recurrent pain. Pain intensity was positively correlated (r = .14) with depression among the students who reported having recurrent pain. Implications of the findings for future research, treatment, and health promotion efforts are discussed.     

Construction and selection of tightened-normal-tightened sampling inspection scheme of type TNT-(n1, n2; c)

A table is presented for the construction and selection of tightened-normal-tightened sampling scheme of type TNT-(n1, n2;c). Efficiency of TNT-(n1, n2;c) scheme over conventional single and double sampling plans is discussed.