Estimating the discovery rate in a continuous time recapture model

We consider a family of marked Poisson process models for the discovery of distinct errors in a computer program and also for sampling, in continu-ous time, a population containing an unknown number of distinct biological species. Captures (selections or discoveries) are assumed to occur at a con-stant rate, each event consisting of the discovery of a distinct process (error or species) or the recurrence of a previously discovered process. Using a generalization of Nayak’s (1988) model we derive confidence limits for the discovery rate. The limits are based on the asymptotic distribution of a scaled logarithmic function of the maximum likelihood estimator.     

Amemiya‘s generalized least squares and tests of overidentification in simultaneous equation models with qualitative or limited dependent variables

Amemiya's generalized least squares method for the estimation of simultaneous equation modeis with qualitative or limited dependent variables is known to be efficient relative to many popular two stage estimators. This note points out that test statistics for overidentification restrictions can be obtained as by-products of Amerniya's generalized least squares procedure. Amemiya's procedure is shown to be a minimum chisquare method. The Amemiya procedure is valuable both for efficient estimation and for model evaluation of such models.     

Exchange option in a two-state Poisson CAPM

In this paper we derive the pricing formula for the exchange option value in a two-state Poisson CAPM. A two-state Poisson CAPM models the stochastic market environment. We also provide examples and graphs to illustrate our result.     

Comparison of conditional and unconditional confidence intervals for the double exponential distribution

Conditional confidence intervals for the location parameter of the double exponential distribution based on maximum likelihood estimators conditioned on a set of ancillary statistics and the corresponding unconditional confidence intervals based on the maximum likelihood estimators alone are compared in two ways. Monte Carlo techniques are used and the conditional approach appears to give slightly better results although agreement as n becomes larger is noted     

New approximate confidence intervals for the difference between two Poisson means and comparison

The problem of estimating the difference between two Poisson means is considered. A new moment confidence interval (CI), and a fiducial CI for the difference between the means are proposed. The moment CI is simple to compute, and it specializes to the classical Wald CI when the sample sizes are equal. Numerical studies indicate that the moment CI offers improvement over the Wald CI when the sample sizes are different. Exact properties of the CIs based on the moment, fiducial and hybrid methods are evaluated numerically. Our numerical study indicates that the hybrid and fiducial CIs are in general comparable, and the moment CI seems to be the best when the expected total counts from both distributions are two or more. The interval estimation procedures are illustrated using two examples.     

Point estimation after early stopping in a repeated measures trial

When the individual measurements are statistically independent, the maximum likelihood estimator calculated at the end of a sequential procedure overestimates the underlying effect. There are many clinical trials in which we are interested in comparing changes in responses between two treatment groups sequentially. Lee and DeMets (1991, JASA 86, 757–762) proposed a group sequential method for comparing rates of change when a response variable is measured for eaeh patient at successive follow-up visits. They assumed that the response follows the linear mixed effects model and derived the asymptotic joint distribution of the sequentially computed statistics. In this article, we consider the maximum likelihood estimator (MLE), the median unbiased estimator (MUE) and the midpoint of a 100(1-α)% confidence interval as point estimators for the rate of change in the linear mixed effects model, and investigate their properties by Monte Carlo simulation.