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21.
Twin studies represent an important and powerful approach to estimating the relative contributions of environmental and genetic factors to the expression of psychiatric illnesses. In this article, we first explain the rationale for using large populations of monozygotic and dizygotic twin pairs to estimate genetic and environmental contributions to a disorder and the statistical modeling associated with this approach. We then review results from studies of the Vietnam Era Twin Registry that use this methodology to examine the etiology of pathological gambling (PG) behaviors. The results provide strong evidence for genetic contributions to the development of PG in men and set the foundation for future studies aimed at identifying the manner in which specific genes and environmental factors individually and in conjunction contribute to PG.  相似文献   
22.
This research proposes a multi-criteria decision-making (MCDM) framework and demonstrates the impact of competitive conditions on supplier evaluation process for construction supply chains. The paper focuses on the supply chain of a large-scale housing project in order to illustrate the role of competitive capability and suppliers’ profile and its influence on supplier evaluation based on prevailing supply/market conditions. Various scenarios are investigated to demonstrate the impact of competition on supplier evaluation. The contribution of the study lies in highlighting the impact of supply/market conditions on MCDM decisions causing supplier evaluation ‘imbalance’ and MCDM usage. It is expected that the study will be useful for project management, construction, supply chain management, sourcing professionals. The findings of the study are generalisable to projects-based situations such as petroleum refinery and ship building where bill of materials typically consists of thousands of items and a large number of suppliers are involved.  相似文献   
23.
Critical infrastructure systems must be both robust and resilient in order to ensure the functioning of society. To improve the performance of such systems, we often use risk and vulnerability analysis to find and address system weaknesses. A critical component of such analyses is the ability to accurately determine the negative consequences of various types of failures in the system. Numerous mathematical and simulation models exist that can be used to this end. However, there are relatively few studies comparing the implications of using different modeling approaches in the context of comprehensive risk analysis of critical infrastructures. In this article, we suggest a classification of these models, which span from simple topologically‐oriented models to advanced physical‐flow‐based models. Here, we focus on electric power systems and present a study aimed at understanding the tradeoffs between simplicity and fidelity in models used in the context of risk analysis. Specifically, the purpose of this article is to compare performance estimates achieved with a spectrum of approaches typically used for risk and vulnerability analysis of electric power systems and evaluate if more simplified topological measures can be combined using statistical methods to be used as a surrogate for physical flow models. The results of our work provide guidance as to appropriate models or combinations of models to use when analyzing large‐scale critical infrastructure systems, where simulation times quickly become insurmountable when using more advanced models, severely limiting the extent of analyses that can be performed.  相似文献   
24.
25.
The purpose of this study was to examine the influence of abuse and parental characteristics on attributional content and determine the relative contribution of different attributions of blame in predicting psychological symptomatology among adult survivors of childhood sexual abuse. One hundred eighty-three female undergraduates with a history of childhood sexual abuse completed self-report questionnaires. Abuse characteristics were significantly related to attributions. Family- and perpetrator-blame accounted for significant variability in psychological symptomatology, beyond the contributions of abuse characteristics, family environment, and self-blame. Implications for research and treatment are discussed.  相似文献   
26.
ABSTRACT

The Society for Adolescent Health and Medicine emphasizes the need for research to focus on the health outcomes of sexual minority youth (i.e., lesbian, gay, bisexual, transgender, queer). However, sexual minority youth (SMY) are often less willing to participate in research studies where parental consent is required due to potential victimization and discrimination. This is a major concern given that more research is needed to understand the health needs of this population, especially in terms of suicide, substance use, and HIV prevention. The National Suicide Prevention Strategy classifies SMY as a high-risk group, emphasizing the need to explore suicide risks (along with other health outcomes) among this group. However, this high-risk classification also increases the safeguards necessary to conduct research with this population. Many researchers have argued for waivers of parental consent, but such waivers present with several ethical implications. This article discusses ethical principles, risks, benefits, safeguards, and potential alternative approaches to waivers of parental consent for SMY. We conclude by emphasizing the need for policy changes to allow parental consent waivers for research targeting SMY.  相似文献   
27.
Black D  Gates G  Sanders S  Taylor L 《Demography》2000,37(2):139-154
This work provides an overview of standard social science data sources that now allow some systematic study of the gay and lesbian population in the United States. For each data source, we consider how sexual orientation can be defined, and we note the potential sample sizes. We give special attention to the important problem of measurement error, especially the extent to which individuals recorded as gay and lesbian are indeed recorded correctly. Our concern is that because gays and lesbians constitute a relatively small fraction of the population, modest measurement problems could lead to serious errors in inference. In examining gays and lesbians in multiple data sets we also achieve a second objective: We provide a set of statistics about this population that is relevant to several current policy debates.  相似文献   
28.
This cross-sectional, secondary analysis study utilizes data from a prior study of intergenerational substance use among Latina women (n = 316). We explored the influence of substance use frequency and type, as well as cultural and socioeconomic factors on attributions about addiction among a predominantly immigrant sample of Latina women. Women who were less proficient in English (an indicator of adoption of the receiving culture in the acculturation process) and more proficient in Spanish (an indicator of heritage-culture retention) endorsed more spiritual model attributions than women who were more proficient in English and less proficient in Spanish. Women were more proficient in Spanish more frequently endorsed the disease attribution model. Alcohol, marijuana use and non-medical sedative use were linked with spiritual, moral /character and disease attribution models respectively. Participants reporting higher education levels indicated less agreement with the moral/character model of addiction. Implications for culturally tailored social work interventions for Latina women are discussed.  相似文献   
29.
The purpose of this study is to demonstrate how packaging postponement can be effectively leveraged in a dynamically changing diverse retail market where responsiveness is key. The study also guides about the empirical evaluation of how packaging postponement affects the performance in the sanitary pads supply chain by considering operating measures. The focal company belongs to the Indian Fast Moving Consumer Goods sector, hygiene products category. It examines the measures that are critical to a responsive supply chain and presents a comparative analysis of selected measures before and after implementation. The findings illustrate that the packaging postponement not only improves competitive advantage but also significantly contributes to improving product proliferation and supply chain responsiveness. The study provides understanding of drivers and obstacles for packaging postponement strategy with operational insights about ‘how-to’ implement. Most of modelling-based research studies justify the adoption of postponement through savings in inventory only and underplay on other operating measures. While justifying, studies emphasise ‘form’/manufacturing aspects and underestimate the packaging aspects of postponement. This paper addresses these gap areas by systematically highlighting prerequisites and demonstrates the benefits of adopting a packaging strategy to handle variety and responsiveness in an emerging economy.  相似文献   
30.
Motivational enhancement therapy (MET) interventions are being increasingly added to the menu of behavioral interventions for HIV prevention. They present few logistical and psychological barriers for at-risk persons who are ambivalent about transmission risk reduction and appear to offer promise of being transferable to community based organizations and public health programs. We describe the principles of motivational interviewing, a counseling style often used in conjunction with MET, and demonstrate and discuss its application with case examples drawn from a recent pilot trial of a telephone-delivered brief motivational enhancement for HIV risk reduction with men who have sex with men (MSM).  相似文献   
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