The influence of FDA advisory information and black box warnings on individual use of prescription antidepressants

We examine how use of antidepressant medications is influenced by Food and Drug Administration (FDA) warnings about the increased risk of suicidality associated with pediatric antidepressant use. With individual-level data on antidepressant use from the Medical Expenditure Panel Survey, we consider whether consumer responses to FDA warnings differ among targeted (children) and non-targeted (adult) age-groups. Because the warning labels specifically mentioned new users, we examine separately the effects of the warnings on initiations of antidepressant therapy and on continued use of antidepressants. We find evidence consistent with reduced initiation of antidepressant use among the intended population of children, and that usage among children with more highly educated parents responded earlier to FDA information. However, we also find spillover effects of reduced initiation among the non-targeted population of adults. Overall, our results indicate that the FDA warning may have led consumers to perceive risks beyond those specifically mentioned.     

The Progression of Sexual Relationships

The authors examine factors associated with the advancement or dissolution of newly formed sexual relationships. Data from the 2006–2010 National Survey of Family Growth (NSFG) was used to examine women and men aged 18–39 (n = 2,774) whose most recent sexual relationship began within the 12 months before their interview. Results indicate that newly formed sexual relationships are often transitory. By 12 months, only 23% of respondents remained in nonresidential sexual relationships, another 27% were cohabiting with that partner, and half had ended their relationships. Sexual relationships formed before age 25 are significantly more likely to break up than to transition into cohabitation. Indicators of social class disadvantage, such as living with a stepparent, expedited cohabitation, whereas measures of advantage, such as having a college‐educated mother, deterred transitions into shared living. Racial differences also emerge: Blacks were less likely than Whites to transition rapidly into shared living.     

Parental Divorce,Residence Arrangements,and Contact Between Grandchildren and Grandparents

When parents divorce, grandparents can play a supportive role in the lives of their grandchildren, but a parental divorce may also put grandchild–grandparent ties under pressure. In this study the authors investigated how grandchildren of married and divorced parents differ in the frequency of face‐to‐face contacts with grandparents and how this is mediated by postdivorce residence arrangements. Based on the multi‐actor survey “Divorce in Flanders,” they used reports of contact provided by more than 1,000 grandchildren and compared them with more than 1,100 grandparent reports for validation. The results showed that grandchildren from divorced parents have fewer contacts with their grandparents than grandchildren whose parents are married but that it is the postdivorce residence arrangement of grandchildren that produces this result. When grandchildren live with their divorced father or in a shared residence arrangement, they even see paternal grandparents more often than grandchildren with married parents.     

Implicit and Explicit Sexual Attitudes: How Are They Related to Sexual Desire and Sexual Satisfaction in Men and Women?

This article examines individual variability in sexual desire and sexual satisfaction by exploring the relation between these sexual aspects and sexual attitudes (implicit and explicit) and by taking gender into account, as this has been shown to be an influential factor. A total of 28 men and 33 women living in heterosexual relationships completed questionnaires assessing sexual desire (dyadic, solitary), sexual satisfaction, and explicit sexual attitudes. An adapted version of the Affect Misattribution Procedure was used to assess implicit sexual attitudes. Results showed higher levels of dyadic and solitary sexual desire in men than in women. No gender differences were found regarding sexual satisfaction or sexual attitudes. High dyadic sexual desire was associated with positive implicit and explicit sexual attitudes, regardless of gender. However, solitary sexual desire was significantly higher in men than women and was associated, in women only, with positive implicit sexual attitudes, suggesting that solitary sexual desire may fulfill different functions in men and women. Finally, sexual satisfaction depended on the combination of explicit and implicit sexual attitudes in both men and women. This study highlights the importance of considering both implicit and explicit sexual attitudes to better understand the mechanisms underlying individual variability in sexual desire and satisfaction.     

Reconfigured Everyday Lives of Children from Divorced-Parent Families in Singapore

With the termination of a marriage, children involved inevitably experience dramatic changes in different facets of their lives. This article makes use of narrative accounts of divorced single parents to investigate how their marital dissolution has impacted and changed their children's lives. Empirical data was collected through semi-structured, in-depth interviews with 25 Singaporean divorced parents. Within the policy and social context of Singapore society, I highlight transformations in three specific aspects of the children's lives: one, the reconfigurations of familial relationships and formation of a new family unit; two, the creation of and adaptation to new family practices and routine; three, the adoption of new social identity following parental divorce. This article hopes to present a more nuanced understanding of the divorce experience by emphasizing both the precarious and productive aspects in the children's lives, contra to the existing divorce literature that typically focuses on the former.     

Quality of work and job satisfaction: comparing female part-time work in four European countries

Adding to the debate on the integrative or marginalizing nature of female part-time work, this article provides a comparative analysis of the implications of female part-time work for different intrinsic job quality dimensions and job satisfaction. Drawing on national micro-data from Britain, Germany, the Netherlands, and Sweden, our multivariate analyses show cross-national similarities in terms of lower job learning opportunities for female part-timers. We found a significantly higher incidence of repetitiveness only among Swedish female part-timers and lower degrees of task discretion among British, Dutch, and Swedish women working part-time hours. Female part-timers were either equally satisfied with their work as female full-timers or even more satisfied. This held true also after accounting for the lower intrinsic job quality of part-time work. While women working part-time hours were as affected by their job quality characteristics as were full-timers, we conclude that the shorter hours of work per se provide an important additional source of job satisfaction.     

NPO Financial Statement Quality: An Empirical Analysis Based on Benford’s Law

In order to assess the accuracy of the figures reported in NPOs’ financial statements, I perform a digital analysis on Belgian non-profit organizations’ financial statements for accounting years 2007 up to 2012. Specifically, I compare observed frequencies for digits in the second-from-the-left position with expected frequencies based on Benford’s Law. Results based on the full sample indicate that observed frequencies strongly conform to Benford’s Law (and thus suggest a high degree of accuracy of the figures reported in NPOs’ financial statements). Nevertheless, I note statistically significant deviations from Benford’s Law (both for the entire distribution and at the individual digit level). The largest deviation is noted for zeroes in the second position (i.e., a significantly positive deviation), which can be explained based on humans’ reliance upon so-called cognitive reference points. Considering different sub-samples, I note that observed deviations from Benford’s Law are largest for the smallest non-profits and those non-profits that rely most heavily on grants and/or donations.     

Women Elite Leaders Doing Respectable Business Femininity: How Privilege is Conferred,Contested and Defended through the Body

This paper offers a theory of respectable business femininity. Respectable business femininity is theorized as a discursive and relational process that explains tensions women elite leaders experience at the nexus of being both One and Other and sometimes privileged, embedded notions of leadership as masculine and wider expectations of acceptable embodied femininity. Such tensions manifest through a disciplining of women leaders’ bodies and appearance by self‐and‐others, as a means of appraising women as credible elite leaders and respectable women. Through a qualitative study we show how, within sites of ambiguity, embodied leadership and subjectivities are both enabled and constrained. Accounts highlight how privilege is fluid and (de)stabilized in that it is conferred, contested and defended through women's bodies and appearance. We advance understandings of contemporary respectable femininity, privilege at work, and body work, and consider practical implications for women leaders and management education.     

COST INCREASES DUE TO DEMAND UNCERTAINTY IN MRP LOT SIZING

This paper analyzes the cost increases due to demand uncertainty in single-level MRP lot sizing on a rolling horizon. It is shown that forecast errors have a tremendous effect on the cost effectiveness of lot-sizing techniques even when these forecast errors are small. Moreover, the cost differences between different techniques become rather insignificant in the presence of forecast errors. Since most industrial firms face demand uncertainty to some extent, our findings may have important managerial implications. Various simulation experiments give insight into both the nature and the magnitude of the cost increases for different heuristics. Analytical results are developed for the constant-demand case with random noise and forecasting by exponential smoothing. It is also shown how optimal buffers can be obtained by use of a simple model. Although the analysis in this paper is restricted to simplified cases, the results merit further consideration and study. This paper is one of the first to inject forecast errors into MRP lot-sizing research. As such it attempts to deal with one of the major objections against the practical relevance of previous research in this area.     

马尼拉、澳门、广州:紧密相联的三座城市

数百年来,马尼拉、澳门和广州一直相互依存,保持着密切关系。从16世纪后期至今,三者有着紧密的互动关系,每一城市对其他两者都有着深刻的影响与冲击。这些联系已经维系了几百年,直到今天仍有数万菲律宾人在珠江三角洲生活和工作。牛痘传入澳门和广州或许是巴尔米斯环球之旅的意外收获,但它也确实是三个地区之间长期密切关系的一个表现。在巴尔米斯来到珠江三角洲200周年之际,我们不应忘记三地人民之间在历史上的紧密关系,这一关系仍继续支持和维系着中菲两国,它也将把我们带向未来。