An Empirical Study of Statistical Properties of Variance Partition Coefficients for Multi-Level Logistic Regression Models

Partitioning the variance of a response by design levels is challenging for binomial and other discrete outcomes. Goldstein (2003 Goldstein , H. ( 2003 ). Multilevel Statistical Models. 3rd ed . London : Edward Arnold . [Google Scholar]) proposed four definitions for variance partitioning coefficients (VPC) under a two-level logistic regression model. In this study, we explicitly derived formulae for multi-level logistic regression model and subsequently studied the distributional properties of the calculated VPCs. Using simulations and a vegetation dataset, we demonstrated associations between different VPC definitions, the importance of methods for estimating VPCs (by comparing VPC obtained using Laplace and penalized quasilikehood methods), and bivariate dependence between VPCs calculated at different levels. Such an empirical study lends an immediate support to wider applications of VPC in scientific data analysis.     

On Fan's adaptive Neyman tests for comparing two spectral densities

In this paper, we consider tests for assessing whether two stationary and independent time series have the same spectral densities (or same autocovariance functions). Both frequency domain and time domain test statistics for this purpose are reviewed. The adaptive Neyman tests are then introduced and their performances are investigated. Our tests are adaptive, that is, they are constructed completely by the data and do not involve any unknown smoothing parameters. Simulation studies show that our proposed tests are at least comparable to the current tests in most cases. Furthermore, our tests are much more powerful in some cases, such as against the long orders of autoregressive moving average (ARMA) models such as seasonal ARMA series.     

Comparison of One-Sided Tolerance Limits in Unbalanced One-Way Random Models

Cox's discrete logistic model was extended to the study of the life table by Thompson (1977) to handle grouped survival data. Inferences about the effect of grouping are studies byMonte Carlo methods. The results show that the effect of grouping is not substantial. This approach is applied to the grouped data on liver cancer. The computer program developed for grouped censored data with continuous and indicator covariates is of practical importance and is available fromThe Ohio State University     

Comparison of Confidence Intervals on Between Group Variance in Unbalanced Heteroscedastic One-Way Random Models

A computer algorithm for computing the alternative distributions of the Wilcoxon signed rank statistic under shift alternatives is discussed. An explicit error bound is derived for the numeric integration approximation to these distributions.

A nonparametric process control procedure in which the standard CUSUM procedure is applied to the Wilcoxon signed rank statistic is discussed. In order to implement this procedure, the distribution of the Wilcoxon statistic under shift of the underlying distribution from its point of symmetry needs to be computed. The average run length of the nonparametric and parametric CUSUM are compared.     

Positive False Discovery Rate Estimate in Step-Wise Variable Selection

Selecting predictors to optimize the outcome prediction is an important statistical method. However, it usually ignores the false positives in the selected predictors. In this article, we advocate a conventional stepwise forward variable selection method based on the predicted residual sum of squares, and develop a positive false discovery rate (pFDR) estimate for the selected predictor subset, and a local pFDR estimate to prioritize the selected predictors. This pFDR estimate takes account of the existence of non null predictors, and is proved to be asymptotically conservative. In addition, we propose two views of a variable selection process: an overall and an individual test. An interesting feature of the overall test is that its power of selecting non null predictors increases with the proportion of non null predictors among all candidate predictors. Data analysis is illustrated with an example, in which genetic and clinical predictors were selected to predict the cholesterol level change after four months of tamoxifen treatment, and pFDR was estimated. Our method's performance is evaluated through statistical simulations.     

More on the Preliminary Test Estimator in Almost Unbiased Liu Regression

This article is concerned with the parameter estimation in linear regression model when it is suspected that the regression coefficients are the subspace of the equality restrictions. The objective of this article is to introduce the preliminary test almost unbiased Liu estimators (PTAULE) based on the Wald (W), the likelihood ratio (LR), and the Lagrangian multiplier (LM) tests and compare the proposed estimators in the sense of the quadratic bias and mean square error (MSE) criterion.     

An Extension of Economic Design of x-Bar Control Charts for Non Normally Distributed Data Under Weibull Shock Models

Three parameters—sample size, sampling intervals, and the control limits—must be determined when the x bar chart to monitor a manufacturing process. The constant sampling intervals were widely employed because of its administrative simplicity. However, the variable sampling interval (VSI) has recently been shown to give substantially faster detection of most process shifts than fixed-sampling-interval (FSI) for x-bar charts. In addition, these measurements in the subgroup are assumed to be normally distributed. That assumption may not be tenable. This investigation compares the economic design of x-bar control charts for non normal data under Weibull shock models with various sampling avenues.     

Spatial Cluster Detection for Longitudinal Outcomes Using Administrative Regions

This article proposes a new spatial cluster detection method for longitudinal outcomes that detects neighborhoods and regions with elevated rates of disease while controlling for individual level confounders. The proposed method, CumResPerm, utilizes cumulative geographic residuals through a permutation test to detect potential clusters which are defined as sets of administrative regions, such as a town or group of administrative regions. Previous cluster detection methods are not able to incorporate individual level data including covariate adjustment, while still being able to define potential clusters using informative neighborhood or town boundaries. Often, it is of interest to detect such spatial clusters because individuals residing in a town may have similar environmental exposures or socioeconomic backgrounds due to administrative reasons, such as zoning laws. Therefore, these boundaries can be very informative and more relevant than arbitrary clusters such as the standard circle or square. Application of the CumResPerm method will be illustrated by the Home Allergens and Asthma prospective cohort study analyzing the relationship between area or neighborhood residence and repeated measured outcome, occurrence of wheeze in the last six months, while taking into account mobile locations.     

Bonferroni-type Plug-in Procedure Controlling Generalized Familywise Error Rate

Consider the multiple hypotheses testing problem controlling the generalized familywise error rate k-FWER, the probability of at least k false rejections. We propose a plug-in procedure based on the estimation of the number of true null hypotheses. Under the independence assumption of the p-values corresponding to the true null hypotheses, we first introduce the least favorable configuration (LFC) of k-FWER for Bonferroni-type plug-in procedure, then we construct a plug-in k-FWER-controlled procedure based on LFC. For dependent p-values, we establish the asymptotic k-FWER control under some mild conditions. Simulation studies suggest great improvement over generalized Bonferroni test and generalized Holm test.     

The adaptive calibration of testing p-values

Abstract

In statistical hypothesis testing, a p-value is expected to be distributed as the uniform distribution on the interval (0, 1) under the null hypothesis. However, some p-values, such as the generalized p-value and the posterior predictive p-value, cannot be assured of this property. In this paper, we propose an adaptive p-value calibration approach, and show that the calibrated p-value is asymptotically distributed as the uniform distribution. For Behrens–Fisher problem and goodness-of-fit test under a normal model, the calibrated p-values are constructed and their behavior is evaluated numerically. Simulations show that the calibrated p-values are superior than original ones.