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61.
During their follow-up, patients with cancer can experience several types of recurrent events and can also die. Over the last decades, several joint models have been proposed to deal with recurrent events with dependent terminal event. Most of them require the proportional hazard assumption. In the case of long follow-up, this assumption could be violated. We propose a joint frailty model for two types of recurrent events and a dependent terminal event to account for potential dependencies between events with potentially time-varying coefficients. For that, regression splines are used to model the time-varying coefficients. Baseline hazard functions (BHF) are estimated with piecewise constant functions or with cubic M-Splines functions. The maximum likelihood estimation method provides parameter estimates. Likelihood ratio tests are performed to test the time dependency and the statistical association of the covariates. This model was driven by breast cancer data where the maximum follow-up was close to 20 years.  相似文献   
62.
Coaching has become an integral part of systematic management development. This article describes the successful implementation of an individual coaching as an essential element in a leadership development program, that is based on the author’s practical experience. Moreover, the article presents the conceptual framework of the development program, the understanding of coaching and the underlying process. Effective internal marketing, transparency about the coaching process and an emphasis on voluntary compliance are emerging as success factors for the sustainable establishment of the coaching offer.  相似文献   
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Recent years have seen increased attention paid to monitoring social anomie and its dependency on micro- and macro-factors. In this paper, we endorse the theorisation of social anomie as a complex, multidimensional and multilevel phenomenon. To ensure a rigorous measurement of the varying levels of social anomie in the European countries, the current study relies on a multilevel multidimensional item response theory model which explicitly accounts for the presence of a non-ignorable missing data mechanism. This unified approach makes it possible to specify an analytical model of links between anomie features and their determinants and to explore how the latent traits of interest are influenced by individual-level factors, as well as by country-level indicators. Additionally, to avoid misleading inferential conclusions, the proposed model takes into account the respondent’s omitting behaviour, assuming that the missingness mechanism is driven by a latent propensity to respond. Data used in this study have been collected in the 2010 wave of the European Social Survey. To reduce the computational complexities, a Bayesian specification of the MIRT model is provided and the parameter model estimates are obtained through MCMC algorithms.  相似文献   
65.
This article analyzes infanticide based on the Coroners' Records for Providence County, Rhode Island, from the 1870s to 1938 to determine doctors' and coroners' attitudes toward mothers who killed. The nineteenth century witnessed a medical discourse on the possibility of postpartum insanity as a cause of infanticide. While some women claimed temporary insanity, and some doctors and coroners legitimated this defense, its application to mothers who killed was arbitrary. They determined who deserved this diagnosis based on the woman's character, her forthrightness, and extenuating circumstances. Infanticide divided the profession nationally and at the local level and prevented doctors or coroners from speaking in a united voice on the issue. This article does not attempt to follow cases of infanticide through to jury verdicts. Instead, it provides an opportunity to analyze the circumstances women faced that led them to kill their newborns, and to analyze the responses of doctors and coroners to these mothers who killed. Unlike the findings of other studies, neither physicians nor coroners in Rhode Island were united in a claim of ignorance to save these women from guilty verdicts.  相似文献   
66.
While it is generally agreed that income inequality affects an individual’s well-being, researchers disagree on whether people living in areas of high income disparity report more or less happiness than those in more equal environments, thereby indicating the need to study how and why income inequality matters to the individual’s well-being. Findings on group-specific reaction patterns to income inequality further fuel this need. Alesina et al. (2004) argue that a preference for inequality and the perception of the possibility of social mobility account for the indistinct relationship between income inequality and subjective well-being. Combining this hypothesis with previous research on social cognition and drawing on social justice theory, this paper aims to demonstrate the mediating nature of perceptions of income inequality. It argues that the perceived legitimacy of distributive outcomes and procedures contributes to how income inequalities affect individuals and their sense of well-being. The empirical analysis is based on data from the International Social Justice Project, developed from face-to-face interviews with a representative sample of the German population. Using structural equation modeling, the paper finds structural biases in the perception of income inequality. The paper concludes that subjective well-being is a product of the individual’s perception and legitimating processes. The results indicate that social cognition is a useful tool for studies of income inequality and subjective well-being.  相似文献   
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It is believed that health and safety of workers should be worked with children and early teenagers, the perspective that adults are more aware of these issues by providing them with health and quality of life in their daily lives, this is want the ERGOSHOW. The choice of media means for transmitting content of Ergonomics, Health and Safety (OSH) is justified because of the great popularity of computer games are among the public of the study, thereby providing a greater assimilation of the content worked. Therefore, the aim of this study was to work with OSH issues related to children between 08 and 12 years old, city of, State of Minas Gerais, Brazil. To achieve this we used the software ERGOSHOW, quizzes, and lecture. One can see that the use of multimedia tools in the learning, especially when considering the reports of mothers according to the different behavior of children after the development of activities, such as parents in correcting posture in relation to computer use.  相似文献   
69.
This paper presents an analysis of cognitive-ergonomic aspects of e-learning courses, offered by an organism from Brazilian Public Administration. The Cognitive Ergonomic studies conductive and cognitive aspects concerning to the relation between human, physics elements and social elements of the work space. From that usability aspects were evaluated by these points: i) visualization; ii) text comprehension lecture; iii) memory; iv) interface; v) instructional design; and vi) attention and learning. That survey is characterized as having been applied using the following techniques: (1) bibliographic survey, (2) field survey and (3) analysis of the documents. It was chosen the semi-structured questionnaire as the main method of data collection. About the interacting with artifacts, the interface of the courses is classified as direct engagement, because it allows the user to get the feeling that acts directly on the objects. Although the courses are well-structured they have flaws that will be discussed below. Even with these problems, the courses have a good degree of usability.  相似文献   
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