Attribution of tumour lethality and estimation of the time to onset of occult tumours in the absence of cause-of-death Information

A new statistical approach is developed for estimating the carcinogenic potential of drugs and other chemical substances used by humans. Improved statistical methods are developed for rodent tumorigenicity assays that have interval sacrifices but not cause-of-death data. For such experiments, this paper proposes a nonparametric maximum likelihood estimation method for estimating the distributions of the time to onset of and the time to death from the tumour. The log-likelihood function is optimized using a constrained direct search procedure. Using the maximum likelihood estimators, the number of fatal tumours in an experiment can be imputed. By applying the procedure proposed to a real data set, the effect of calorie restriction is investigated. In this study, we found that calorie restriction delays the tumour onset time significantly for pituitary tumours. The present method can result in substantial economic savings by relieving the need for a case-by-case assignment of the cause of death or context of observation by pathologists. The ultimate goal of the method proposed is to use the imputed number of fatal tumours to modify Peto's International Agency for Research on Cancer test for application to tumorigenicity assays that lack cause-of-death data.     

Construction of central composite designs for balanced orthogonal blocks

Box & Hunter (1957) recommended a set of orthogonally blocked central composite designs (CCD) when the region of interest is spherical. In order to achieve rotatability along with orthogonal blocking, the block size for those designs becomes unequal and it may not be attractive or practical to use such unequally blocked designs in many practical situations. In this paper, a construction method of orthogonally blocked CCD under the assumption of equal block size is proposed and an index of block orthogonality is introduced.     

Understanding the antecedents of aggressive behavior in Persian Gulf War veterans within individual,interpersonal, and community contexts

ABSTRACT

The present study applies the social-ecological framework to examine multiple level correlates of aggressive behavior of veterans of the first Gulf War in 1991. Data were collected from the VA‘s Persian Gulf Family Support Programs (PGFSP), and the sample includes 1,519 veterans who participated in the PGFSP. At the individual level, the study finds that younger and female veterans and those with higher self-esteem were less likely to report displaying aggressive behavior. At the interpersonal level, veterans who displayed misconduct in the home are more likely to display aggressive behavior. At the community level, veterans who were in the Air Force was less likely, while those in the Marines were more likely to be aggressive. Implications for practice are discussed.     

Powerful emotions: symbolic power and the (productive and punitive) force of collective feeling

This article argues that emotions can be a medium of social power. Using qualitative interview material from American Jews discussing anti-Semitism and its relationship to contemporary politics, it engages recent scholarship on emotions and political contention and shows how emotions make effective the various forms of symbolic exclusion by which group members exercise what Bourdieu calls symbolic power. It also explores the emotional connections to group membership by which some “excluded” members can engage in symbolic struggle over “the principles of vision and division” Bourdieu (Sociological Theory 7(1), 14–25, 1989) that define the group. Finally, it shows how emotions work to incite discipline in some group members, inspiring them to conform to dominant definitions of group membership so as to avoid both symbolic struggle and exclusion.     

The Clash between Social Policy and Traditional Values: Unmet Welfare Needs Sustained by the Culture of Familism in South Korea

Drawing from a wider study of the ideas of poverty and inequality in South Korea, this paper reports on the lived experiences of disadvantaged South Koreans and their relationship to the National Basic Livelihood Security System (NBLSS), a flagship social assistance program aimed at addressing poverty and inequality. Utilizing a cultural approach to understanding and analysing policy responses to poverty, the impact of familism in the application of the NBLSS safety net is examined. Research data is presented through the testimonies, obtained through qualitative research interviews, of disadvantaged research participants and those who work with them, as well as policy‐makers' perspectives, revealing key flaws in the current NBLSS policy objectives. It is clearly evident that, by clinging to outdated Confucian conceptualizations of familial piety as a justification for highly selectivist access to what is no more than a subsistence level of financial support for poor people, the proposition of a poverty safety net is compromised and is widely missing its aim of reducing poverty and inequality in contemporary South Korea.     

Self-Regulatory Driving Behaviors: Gender and Transportation Support Effects

This study examined the relationship between transportation support and self-regulatory driving behaviors of 566 community-dwelling older adults living in retirement communities, with a focus on gender differences. The results of logistic regression analysis showed that older women were more likely to avoid driving at night or on the highway than their male counterparts. Transportation support from peer friends was found to increase the likelihood of self-regulatory driving behaviors. The findings of this study imply that transportation policy and driving safety programs for older adults need to be developed, considering available transportation alternatives and gender differences in driving behaviors.     

Importance of pension income of elderly households in Korea and related factors

Utilising the 2014 Household Income and Expenditure Survey of Korea, this study examined the importance of pension incomes for elderly-headed households in Korea and the influence of other income sources and socio-demographic factors on pension income. It was found that 64.8% of those surveyed received pension income, which accounted for 12.4% of total income on average. As age increased, the importance of pension income increased. Pension income receipt and amount were affected by household size, gender, age, educational level and home ownership. Policymakers could use the factors identified in this research to develop effective and selective pension policies.