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31.
This article shows how time works against parents with learningdifficulties in the child protection system and Children Actproceedings. The prevailing wisdom, embedded in policy and theliterature, is that delay in care cases is bad for the childand may jeopardize his or her future. This paper shows how thepressure to avoid delay might itself be harming some families,especially parents with learning difficulties. Drawing on interviewswith social work practitioners undertaken as part of a largerstudy, the authors describe the various forms of temporal discriminationthat impact on this group of disabled parents. They concludethat procedural time limits make it harder for parents withlearning difficulties to meet the standards and expectationsenforced by Childrens Services and the courts. 相似文献
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Tim Dyson 《Population studies》2013,67(2):279-297
Part I of this paper (published in the last issue) was focused on demographic responses to three major famines which occurred in late nineteenth-century India. Part II deals with the 1943–44 famine in Bengal and the 1974–75 famine in Bangladesh. The paper presents important and hitherto unanalysed demographic data on the Bengal famine. Drawing on the analysis of Part I, it argues that because of flaws in the data which have been used, there is a need to reconsider some of the judgements which have been made about the demographic consequences of both the 1943–44 and 1974–75 famines. It is contended that some serious misconceptions have arisen concerning short-term demographic responses to famine. Finally, possible implications for famines in other parts of the world are discussed. 相似文献
34.
Prior information is often incorporated informally when planning a clinical trial. Here, we present an approach on how to incorporate prior information, such as data from historical clinical trials, into the nuisance parameter–based sample size re‐estimation in a design with an internal pilot study. We focus on trials with continuous endpoints in which the outcome variance is the nuisance parameter. For planning and analyzing the trial, frequentist methods are considered. Moreover, the external information on the variance is summarized by the Bayesian meta‐analytic‐predictive approach. To incorporate external information into the sample size re‐estimation, we propose to update the meta‐analytic‐predictive prior based on the results of the internal pilot study and to re‐estimate the sample size using an estimator from the posterior. By means of a simulation study, we compare the operating characteristics such as power and sample size distribution of the proposed procedure with the traditional sample size re‐estimation approach that uses the pooled variance estimator. The simulation study shows that, if no prior‐data conflict is present, incorporating external information into the sample size re‐estimation improves the operating characteristics compared to the traditional approach. In the case of a prior‐data conflict, that is, when the variance of the ongoing clinical trial is unequal to the prior location, the performance of the traditional sample size re‐estimation procedure is in general superior, even when the prior information is robustified. When considering to include prior information in sample size re‐estimation, the potential gains should be balanced against the risks. 相似文献
35.
In studies with recurrent event endpoints, misspecified assumptions of event rates or dispersion can lead to underpowered trials or overexposure of patients. Specification of overdispersion is often a particular problem as it is usually not reported in clinical trial publications. Changing event rates over the years have been described for some diseases, adding to the uncertainty in planning. To mitigate the risks of inadequate sample sizes, internal pilot study designs have been proposed with a preference for blinded sample size reestimation procedures, as they generally do not affect the type I error rate and maintain trial integrity. Blinded sample size reestimation procedures are available for trials with recurrent events as endpoints. However, the variance in the reestimated sample size can be considerable in particular with early sample size reviews. Motivated by a randomized controlled trial in paediatric multiple sclerosis, a rare neurological condition in children, we apply the concept of blinded continuous monitoring of information, which is known to reduce the variance in the resulting sample size. Assuming negative binomial distributions for the counts of recurrent relapses, we derive information criteria and propose blinded continuous monitoring procedures. The operating characteristics of these are assessed in Monte Carlo trial simulations demonstrating favourable properties with regard to type I error rate, power, and stopping time, ie, sample size. 相似文献
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I. Blanchard Jennifer I. Kennode David H. Flaherty Roderick Phillips Tim Curtis Jörg Calliess 《Social history》2013,38(5):661-702
R. H. Hilton, The English Peasantry in the Later Middle Ages (1975), 256 (Clarendon Press, Oxford, £6.50). Colin Platt, The English Medieval Town (1976), 219 (Seeker and Warburg, £6.00). James Axtell, The School Upon A Hill. Education and Society In Colonial New England (1974), xxi+298 (Yale University Press, New Haven, £7.50). Kenneth A. Lockridge, Literacy in Colonial New England. An Enquiry Into The Social Context of Literacy in the Early Modern West (1974), 164 (W. W. Norton and Co., New‐York, $6.95). Jean‐Claude Perrot, Genèse d'une ville moderns. Caen au XVIII'siècle (1975), 2 vols, 1157 (Mouton: Paris, the Hague, 250 fr.). Douglas Hay, Peter Linebaugh and E. P. Thompson (eds.), Albion's Fatal Tree (1975), 344+15 illustrations (Allen Lane, £7.50). E. P. Thompson, Whigs and Hunters (1975), 300+17 illustrations (Allen Lane, £6.50). Arthur E. Imhof (ed.), Historische Demographie als Sozialgeschichte. Giessen und Umgebung (1975), 2 vols, 626+495 (Historische Kommission für Hessen, Darmstadt und Marburg, DM 48). Historical Demography as Social History. Giessen and Surrounding District.1 Alan Forrest, Society and Politics in Revolutionary Bordeaux (1975), xi+300 (Oxford University Press, £8.00). Richard Hunter and Ida Macalpine, Psychiatry for the Poor (1974), 264 (Dawsons of Pall Mall, £4.50, paperback £1.50). Vieda Skultans, Madness and Morals. Ideas on Insanity in the Nineteenth Century (197 5), xv+260 (Routledge and Kegan Paul, £5.50). Thomas S. Szasz, The Age of Madness, The History of Involuntary Mental Hospitalization Presented in Selected Texts (1973), xxi+372 (Routledge and Kegan Paul, £5.95). Harald Runblom and Hans Norman (eds.), From Sweden to America: a History of the Migration (1976), 391 (University of Minnesota Press, Minneapolis, and University of Uppsala). Charlotte Erickson (ed.), Emigration from Europe 1815–1914: Select Documents (1976), 320 (A. and C. Black, £6.50). T. J. Nossiter, Influence, Opinion and Political Idioms in Reformed England: Case Studies from the North‐East, 1832–1874 (1975), xii+255 (Harvester, £7.50). Robert J. Bezucha, The Lyon Uprising of 1834: Social and Political Conflict in the Early July Monarchy (1974), xviii+271 (Harvard University Press, Cambridge, Massachusetts, £6.25). Lawrence Schofer, The Formation of a Modern Labour Force. Upper Silesia, 1865–1914 (1975), xvi+213 (University of California Press, Berkeley, Los Angeles and London, £7.80). Léon Poliakov, The History of Anti‐Semitism. Volume III. From Voltaire to Wagner (1975), x+582 (Routledge and Kegan Paul, no price given). Reinhard Rürup, Emanzipation und Antisemitismus. Studien zur ‘Judenfrage’ der bürgerlichen Gesellschaft (1975), 208 (Vandenhoeck and Rupprecht, Göttingen, paperback DM 28). Uriel Tal, Christians and Jews in Germany. Religion, Politics and Ideology in the Second Reich, 1870–1914 (1975), 359 (Cornell University Press, Ithaca and London, £10.70). Richard S. Levy, The Downfall of the Anti‐Semitic Political Parties in Imperial Germany (1975), 335 (Yale University Press, New Haven and London, no price given). Andrew G. Whiteside, The Socialism of Fools. Georg Ritter von Schönerer and Austrian Pan‐Germanism (1975), x+404 (University of California Press, Berkeley, Los Angeles and London, £15.75). Paul Thompson, The Edwardians: the remaking of British society (1975), xi+382 (Weidenfeld and Nicolson, £10.00). Marc Fried, The World of the Urban Working Class (1975), x+410 (Harvard University Press, Cambridge, Massachusetts, £6.50). Philip Gabriel Eidelberg, The Great Rumanian Peasant Revolt of 1907 (1974), xii+260 (E. J. Brill, Leiden, 64 guilders). Peter H. Mcrkl, Political Violence under the Swastika: 581 Early Nazis (1975), xiv+735 (Princeton University Press, Princeton, $17.50, paper $6.30). 相似文献
40.
Illicit computer intruders, or hackers, are often thought of as pathological individuals rather than as members of a community. However, hackers exist within social groups that provide expertise, support, training, journals and conferences. This article outlines this community to establish the nature of hacking within ‘information societies’. To delineate a ‘sociology of hackers’, an introduction is provided to the nature of computer–mediated communication and the act of computer intrusion, the hack. Following this the hacking community is explored in three sections. First, a profile of the number of hackers and hacks is provided by exploring available demographics. Second, an outline of its culture is provided through a discussion of six different aspects of the hacking community. The six aspects are technology, secrecy, anonymity, membership fluidity, male dominance and motivations. Third, an exploration of the community's construction of a boundary, albeit fluid, between itself and its other, the computer security industry, is provided. This boundary is constructed through metaphors whose central role is to establish the ethical nature of hacking. Finally, a conclusion that rejects any pathologisation of hackers is offered. 相似文献