Dose-Response and Risk Assessment of Airborne Hexavalent Chromium and Lung Cancer Mortality

This study evaluates the dose-response relationship for inhalation exposure to hexavalent chromium [Cr(VI)] and lung cancer mortality for workers of a chromate production facility, and provides estimates of the carcinogenic potency. The data were analyzed using relative risk and additive risk dose-response models implemented with both Poisson and Cox regression. Potential confounding by birth cohort and smoking prevalence were also assessed. Lifetime cumulative exposure and highest monthly exposure were the dose metrics evaluated. The estimated lifetime additional risk of lung cancer mortality associated with 45 years of occupational exposure to 1 microg/m3 Cr(VI) (occupational exposure unit risk) was 0.00205 (90%CI: 0.00134, 0.00291) for the relative risk model and 0.00216 (90%CI: 0.00143, 0.00302) for the additive risk model assuming a linear dose response for cumulative exposure with a five-year lag. Extrapolating these findings to a continuous (e.g., environmental) exposure scenario yielded an environmental unit risk of 0.00978 (90%CI: 0.00640, 0.0138) for the relative risk model [e.g., a cancer slope factor of 34 (mg/kg-day)-1] and 0.0125 (90%CI: 0.00833, 0.0175) for the additive risk model. The relative risk model is preferred because it is more consistent with the expected trend for lung cancer risk with age. Based on statistical tests for exposure-related trend, there was no statistically significant increased lung cancer risk below lifetime cumulative occupational exposures of 1.0 mg-yr/m3, and no excess risk for workers whose highest average monthly exposure did not exceed the current Permissible Exposure Limit (52 microg/m3). It is acknowledged that this study had limited power to detect increases at these low exposure levels. These cancer potency estimates are comparable to those developed by U.S. regulatory agencies and should be useful for assessing the potential cancer hazard associated with inhaled Cr(VI).     

The dilemma of recognition: Administrative categories and cultural diversity

Governments around the world combat inequality by means of group-specific redistribution. Some pursue redistribution that benefits groups, but also wish to avoid accentuating or even recognizing group distinctions. This poses a dilemma that they try to resolve by adjusting the category system used to target redistribution. There are three types of adjustment: accommodation (the multicultural approach), denial (the ideal-typical liberal solution), and replacement (a compromise). In replacement the targets of redistributive policies are constructed to avoid accentuation or recognition of inconvenient group distinctions, but still allow redistribution that benefits these groups. Replacement is increasingly in demand around the world because the disadvantages of multiculturalism are becoming apparent while denial is hard to sustain in the face of group inequality. The actual effect of replacement is little researched and less understood, however. Does it resolve the dilemma of recognition? Two examples–India and Nigeria–where replacement has been tried ever since the 1950s cast doubt on its viability.     

试论宗教对话的层次性、基本中介与普遍模式——三论21世纪基督宗教的对话形态

宗教对话不仅是一个关乎当代人类文明健康发展的大问题 ,而且还是一个关乎当代宗教和平乃至当代和平的大问题。为此 ,我们从学理上阐述宗教对话的层次性、基本中介和普遍模式 ,以及揭露希克宗教多元主义的要害在于宗教对话的“平面化”。     

《红楼梦》80回前后死亡描写之比较

本文主要讨论的是《红楼梦》中重要人物死亡描写的前后比较,以及书中关于死亡意象描写的前后比较。得出的结论是由于作家的生死观、侧重点、创作意图的不同,前80回与后40回中死亡描写的手法是不同的。     

论高等教育社会学研究方法的取向及其本土化建构

一门学科发展的重要意义在于其研究成果与其他相关学科的研究成果往往具有较强的关联性和互补性。对于高等教育社会学而言 ,这一旨趣能否有效实现 ,首先取决于研究者在研究视角与方法的选择方面所体现出来的社会学素养及其自觉性。高等教育社会学的研究方法既要遵行社会学研究的一般策略和原则 ,又要从高等教育的实在特性出发 ,将其研究的目的、策略和方法真正纳入到社会学的研究视域之中 ,从而实现研究方法体系同研究主体、客体和具体环境的高度协同 ,这是实施高等教育社会学本土化建构的基础。     

失范行为的调适之道——根治腐败的社会学思考

腐败是一种社会失范行为。它是权力缺乏制约、私欲恶性膨胀、权力资本化和新旧体制转换共同作用的结果。用社会学视角解决反腐治本问题 ,其思路是完善制度约束人 ,有效监督激励人 ,严法弘德规范人     

明理做人是"思想道德修养"教学的主题

文章抓住明理做人这个主题 ,围绕“思想道德修养”课六个方面的教育内容 ,努力把道理讲明、讲实 ,使学生理解和把握做人的真谛     

探析我国金融控股公司的建立模式与监管制度

金融服务业的变革和一体化,促进了金融集团及金融控股公司的发展。我国金融控股公司有两种模式:非金融企业控股公司和银行控股公司。在监管制度上,强调应实行综合监管与分业监管相结合,从传统监管方式向风险目标值法转移,要制定对金融控股公司资本充足性的监管,建立内部的“防火墙”。     

播音主持有声语言形象感的音声创造

播音主持语言具有音声性的特点,认真分析播音作品中语言的形象感,并通过词语的语音要素用恰当多样的声音将其表现出来,创造出丰富可感的声音形象,可以充分调动受众在视听过程中的各种心理功能。本文细致分析不同文体的播音作品,并对各种文体提出音声创造中的不同要求。     

A genealogy of the disabled identity in relation to work and sexuality

That 'disability' has been central to the formation of the ideal liberal citizen in the modern era can be effectively illuminated by focusing on two prime modes of subjectification, work and sexuality. This paper seeks to demonstrate that a better understanding of their historical involvement in the creation of the disabled identity and their manifestation in recent times in the form of welfare reform and sexual rehabilitation can pave the way for the development of more effective pathways of liberation.

The purpose of history, guided by genealogy, is not to discover the roots of our identity but to commit itself to its dissipation. (Foucault, 1977a, p. 162)