Reference‐based sensitivity analysis for time‐to‐event data

The analysis of time‐to‐event data typically makes the censoring at random assumption, ie, that—conditional on covariates in the model—the distribution of event times is the same, whether they are observed or unobserved (ie, right censored). When patients who remain in follow‐up stay on their assigned treatment, then analysis under this assumption broadly addresses the de jure, or “while on treatment strategy” estimand. In such cases, we may well wish to explore the robustness of our inference to more pragmatic, de facto or “treatment policy strategy,” assumptions about the behaviour of patients post‐censoring. This is particularly the case when censoring occurs because patients change, or revert, to the usual (ie, reference) standard of care. Recent work has shown how such questions can be addressed for trials with continuous outcome data and longitudinal follow‐up, using reference‐based multiple imputation. For example, patients in the active arm may have their missing data imputed assuming they reverted to the control (ie, reference) intervention on withdrawal. Reference‐based imputation has two advantages: (a) it avoids the user specifying numerous parameters describing the distribution of patients' postwithdrawal data and (b) it is, to a good approximation, information anchored, so that the proportion of information lost due to missing data under the primary analysis is held constant across the sensitivity analyses. In this article, we build on recent work in the survival context, proposing a class of reference‐based assumptions appropriate for time‐to‐event data. We report a simulation study exploring the extent to which the multiple imputation estimator (using Rubin's variance formula) is information anchored in this setting and then illustrate the approach by reanalysing data from a randomized trial, which compared medical therapy with angioplasty for patients presenting with angina.     

The Role of Physical Context,Verbal Skills,Non‐parental Care,Social Support,and Type of Parental Discipline in the Development of ToM Capacity in Five‐Year‐Old Children

The aim of this study was to analyze the influence of family context on the performance of 5‐year‐old children (N = 70) in theory of mind (ToM) tasks. The children's performances were assessed during individual sessions held at school. Children's verbal skills were assessed using the Peabody picture vocabulary test (PPVT). Interviews were also conducted with parents in the family home in order to gather sociodemographic data and to assess diverse variables of the family context. In addition to confirming the important role played by children's verbal skills in ToM, the results also supported a potential influence of family context in ToM development through variables, such as quality of non‐parental care or level of social contact and support. The educational implications of these results are discussed in relation to family intervention.     

Putting the Pieces of the Puzzle Together: Age and Sex-Specific Estimates of Migration amongst Countries in the EU/EFTA, 2002–2007

Because of inconsistencies in the reported migration flows and large amounts of missing data, our knowledge of international migration patterns in the Europe is limited. Methods for overcoming data obstacles and harmonising international migration data, however, are improving. In this article, we provide a methodology for integrating various pieces of incomplete information together, including a partial set of harmonised migration flows, to estimate a complete set of migration flows by origin, destination, age and sex for the 31 countries in the European Union and European Free Trade Association from 2002 to 2007. The results represent a synthetic data base that can be used to inform population projections, policy decisions and migration theory.     

Values,Perceived Risks and Benefits,and Acceptability of Nuclear Energy

We examined how personal values and perceptions of risks and benefits are associated with the acceptability of nuclear energy (NE). A theoretical model is tested in which beliefs about the risks and benefits of NE mediate the relationship between values and acceptability. The results showed that egoistic values are positively related to the perceived benefits and acceptability of NE. In contrast, altruistic and biospheric values were positively related to the perceived risks of NE. Although it has been argued that NE may help to combat climate change through lower CO₂ emissions, these environmental benefits were not acknowledged by people with strong biospheric values. Furthermore, results confirmed that the more risks respondents perceived, the less they were inclined to accept NE. In contrast, the more a person believed that NE has beneficial consequences, the more acceptable NE was. Finally, as expected, perceived risks and benefits were found to partly mediate the relationship between personal values and acceptability. We discuss the theoretical and practical implications of these findings.     

An Estimation of the Economic Impact of Migrant Access on GDP: the Case of the Madrid Region

In recent years, the Madrid Region (Comunidad de Madrid) has experienced a huge increase in immigrants accessing the labour market. In this paper, a dynamic input‐output exercise is presented, yielding the direct and indirect effects of this migration inflow on the Madrid GDP. In addition, the induced demand effect is estimated, offering a complete estimate framework of the impact of migrant access on regional value added.     

The wages of sweat: A social history perspective on the fight against sweatshops

The social history of the fight against sweatshops casts light on the current movement in favor of corporate social responsibility. But making the head of a chain of subcontractors responsible for seeing to the well-being of those at the end of the chain is not contemporaneous with present-day globalization and North/South relations. Since the 19th century, when the sweatshop system appeared, those who champion the workers have pointed a finger at those who, though they only exercise indirect control, profit from their exploitation. As our historical analysis emphasizes, though in other contexts the issue of poor working conditions sometimes found solutions that (partially) avoided holding the principal liable, what characterizes the anti-sweatshop movement in the context of globalization is its nearly exclusive focus on bringing pressure to bear on the contractor at the head of the chain.     

Barrieren, Brücken und Balancen

The present paper discusses conceptions of appropriate distance relations in present day service jobs. We show how employees manage their emotions in order to comply with these largely ideological conceptions. In two comparative case studies of a call center and of community care for elderly people we demonstrate that the conceptions of appropriate distance are diametrically opposed to the objective spatial distance of the interactants. Thus, Customer Relations Management suggests an emotionalised relation between customers and call center agents who are located hundreds or even thousands of kilometres away from customers. This emotional closeness supposedly maximises the economic exploitation of the commercial interaction. In the service of elderly care which involves close body contact, however, the conception of a professional relation between carer and client is based on the carer’s ability to distance herself in order not to ‘burn out’. We show that the effects of rationalisation, bureaucratisation and new technologies in service jobs of both capitalist service economies and welfare states create dilemmas between the feeling rules and the working conditions. Service workers try to solve these dilemmas by more or less improvised practices of manipulating their feelings and sensations.