日本的东洋史研究

日本的东洋史研究,中国史占绝对多数。回顾东洋史研究,是按王朝和地域确定研究范围;文学的两大中心东京帝国大学和京都帝国大学有着不同的治学风格;对中国各时代的研究都有代表性的学者涌现。最近证实个别问题的研究较多,题目多种;人们关注新发掘的资料;中日历史学界考察、交流情况越来越多。日本除了在大学增设东洋史专业教育外,还拥有专门的研究机构,刊载东洋史的学术刊物陆续涌现。     

血管生成素通过ERK信号通路促进HeLa细胞的增殖

目的通过细胞外信号调节激酶（extracellularregulatedproteinkinases,ERK）通路及NF-xB信号途径探讨血管生成素（angiogenin,Ang）对HeLa细胞的促增殖及抗凋亡作用机制。方法用不同浓度的重组人Ang刺激HeLa细胞,MTr法分析Ang对HeLa细胞的促增殖作用,蛋白质印迹实验检测ERK信号通路相关分子的表达情况。U0126抑制ERK信号通路,检测Ang诱导的ERKl／2的磷酸化及c—myc的表达情况,同时检测Ang对细胞增殖的影响。敲低Ang的表达,检测细胞的凋亡情况。双荧光素酶报告基因检测Ang对NF-KB报告基因的激活。蛋白水平检测Ang刺激的HeLa细胞后,NF—KB通路相关分子的表达。结果Ang能促进HeLa细胞增殖,ERKl／2的磷酸化水平及c—myc的表达随重组人Ang浓度的升高而增加。U0126能抑制Ang诱导的ERKI／2的磷酸化、c—myc的上调及细胞的增殖。Ang的低表达促进HeLa细胞的凋亡,但不影响NF-KB报告基因的激活及NF—KB通路上相关分子的表达。结论Ang能够促进HeLa细胞增殖,并通过活化ERK通路促进细胞的增殖,但其抑凋亡作用与NF-KB通路无关。     

Impacts of collaboration and network indicators on patent quality: The case of Canadian nanotechnology innovation

This article studies the impact of collaboration and co-inventorship network characteristics of Canadian nanotechnology inventors on the quality of their inventions. We investigate the impact of four types of variables on patent quality, using the number of claims as a proxy for quality: (a) the presence of highly central inventors; (b) the presence of star inventors; (c) repeated collaboration; (d) international collaboration. We show that the presence of more central inventors and of stars in the research team has a positive influence on patent quality, while repeated collaboration has a negative impact. Patents owned by foreign organisations, controlling for whether assignees are firm, yields patents of higher quality.     

西晋末期王浚集团、张轨集团兴衰之比较

本文选择分析王浚集团、张轨集团两个汉族地方武装势力 ,比较它们不同的形成、发展过程 ,探讨它们不同命运的原因 ,进而从一个侧面加深对西晋末期历史的认识     

Lifetime estimation from doubly censored data and dirichlet process prior knowledge on the observable random vector

The purpose of this paper is to present a nonparametric Bayesian procedure for estimating a survival curve in a double censoring situation. Assuming a proportional hazard rates model, we propose a consistent estimation of lifetime, based on a Dirichlet process prior knowledge on the observable random vector. Some large sample properties of this estimator are also derived, We prove strong consistency and asymptotic weak convergence to a Gaussian pro cess. Finally, a simulation study is presented in order to analyze the behavior of the proposed estimator, and establish some comparisons to other estimators.     

“双增”协调运行作用机理研究

以农民增收促进和保证农业增产,实现“双增”目标协调运行的内在机理在于调整农业生产结构,提高质量效益,保障有效供给,增加农民收入,以形成农业发展的持久内在动力。同时也要借助于政府强有力的支持和推动,使内外二力形成合力,达到“双增”目标的实现。