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91.
A Bayesian discovery procedure   总被引:1,自引:0,他引:1  
Summary.  We discuss a Bayesian discovery procedure for multiple-comparison problems. We show that, under a coherent decision theoretic framework, a loss function combining true positive and false positive counts leads to a decision rule that is based on a threshold of the posterior probability of the alternative. Under a semiparametric model for the data, we show that the Bayes rule can be approximated by the optimal discovery procedure, which was recently introduced by Storey. Improving the approximation leads us to a Bayesian discovery procedure, which exploits the multiple shrinkage in clusters that are implied by the assumed non-parametric model. We compare the Bayesian discovery procedure and the optimal discovery procedure estimates in a simple simulation study and in an assessment of differential gene expression based on microarray data from tumour samples. We extend the setting of the optimal discovery procedure by discussing modifications of the loss function that lead to different single-thresholding statistics. Finally, we provide an application of the previous arguments to dependent (spatial) data.  相似文献   
92.
93.
The Tweedie compound Poisson distribution is a subclass of the exponential dispersion family with a power variance function, in which the value of the power index lies in the interval (1,2). It is well known that the Tweedie compound Poisson density function is not analytically tractable, and numerical procedures that allow the density to be accurately and fast evaluated did not appear until fairly recently. Unsurprisingly, there has been little statistical literature devoted to full maximum likelihood inference for Tweedie compound Poisson mixed models. To date, the focus has been on estimation methods in the quasi-likelihood framework. Further, Tweedie compound Poisson mixed models involve an unknown variance function, which has a significant impact on hypothesis tests and predictive uncertainty measures. The estimation of the unknown variance function is thus of independent interest in many applications. However, quasi-likelihood-based methods are not well suited to this task. This paper presents several likelihood-based inferential methods for the Tweedie compound Poisson mixed model that enable estimation of the variance function from the data. These algorithms include the likelihood approximation method, in which both the integral over the random effects and the compound Poisson density function are evaluated numerically; and the latent variable approach, in which maximum likelihood estimation is carried out via the Monte Carlo EM algorithm, without the need for approximating the density function. In addition, we derive the corresponding Markov Chain Monte Carlo algorithm for a Bayesian formulation of the mixed model. We demonstrate the use of the various methods through a numerical example, and conduct an array of simulation studies to evaluate the statistical properties of the proposed estimators.  相似文献   
94.
本文首先选取利率、汇率、股票价格和社会融资规模四个金融变量,建立SVAR模型确定变量权重,构建了量化我国金融状况整体松紧程度的中国金融状况指数.其次,基于已构建指数,引入谱分析方法研究发现:中国金融状况指数与宏观经济景气指数中的一致指数、环比和同比CPI三个指标之间均存在39个月的耦合震荡周期,且中国金融状况指数领先三个指标的期数分别为1.91、0.44和5.5个月,对应一致性统计量的值依次为0.94、0.97和0.96,均接近于1,说明中国金融状况指数对宏观经济景气指数中的一致指数以及对通货膨胀均具有先导性和强相关性,可作为其他宏观经济指标的先行指标.  相似文献   
95.
收入分布函数的研究对于收入不平等的探讨意义重大,但是国内该领域的研究尚待进一步的拓展。笔者在文献回顾的基础上梳理了国外的相关研究,把常用的分布函数分成两参数分布和多参数分布函数两类,介绍了各类函数拟合居民实际收入分布的效果及其与基尼系数的关系;同时,本文剖析了各类函数之间的内在联系;进一步,基于分布函数的角度,笔者研究了收入流动性与收入不平等之间的联系,分析了平均数和中位数比值与基尼系数之间的数学关系以及如何利用该比值来估计分布函数的参数。利用这些研究结果,文章探讨了2010年我国城镇居民的收入结构和贫困问题并提出了一些前瞻性的研究建议。  相似文献   
96.
In high dimensional classification problem, two stage method, reducing the dimension of predictor first and then applying the classification method, is a natural solution and has been widely used in many fields. The consistency of the two stage method is an important issue, since errors induced by dimension reduction method inevitably have impacts on the following classification method. As an effective method for classification problem, boosting has been widely used in practice. In this paper, we study the consistency of two stage method–dimension reduction based boosting algorithm (briefly DRB) for classification problem. Theoretical results show that Lipschitz condition on the base learner is required to guarantee the consistency of DRB. This theoretical findings provide useful guideline for application.  相似文献   
97.
This paper focuses on a novel method of developing one-sample confidence bands for survival functions from right censored data. The approach is model-based, relying on a parametric model for the conditional expectation of the censoring indicator given the observed minimum, and derives its strength from easy access to a good-fitting model among a plethora of choices available for binary response data. The substantive methodological contribution is in exploiting a semiparametric estimator of the survival function to produce improved simultaneous confidence bands. To obtain critical values for computing the confidence bands, a two-stage bootstrap approach that combines the classical bootstrap with the more recent model-based regeneration of censoring indicators is proposed and a justification of its asymptotic validity is also provided. Several different confidence bands are studied using the proposed approach. Numerical studies, including robustness of the proposed bands to misspecification, are carried out to check efficacy. The method is illustrated using two lung cancer data sets.  相似文献   
98.
99.
The semi‐Markov process often provides a better framework than the classical Markov process for the analysis of events with multiple states. The purpose of this paper is twofold. First, we show that in the presence of right censoring, when the right end‐point of the support of the censoring time is strictly less than the right end‐point of the support of the semi‐Markov kernel, the transition probability of the semi‐Markov process is nonidentifiable, and the estimators proposed in the literature are inconsistent in general. We derive the set of all attainable values for the transition probability based on the censored data, and we propose a nonparametric inference procedure for the transition probability using this set. Second, the conventional approach to constructing confidence bands is not applicable for the semi‐Markov kernel and the sojourn time distribution. We propose new perturbation resampling methods to construct these confidence bands. Different weights and transformations are explored in the construction. We use simulation to examine our proposals and illustrate them with hospitalization data from a recent cancer survivor study. The Canadian Journal of Statistics 41: 237–256; 2013 © 2013 Statistical Society of Canada  相似文献   
100.
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