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991.
Comparison of accuracy between two diagnostic tests can be implemented by investigating the difference in paired Youden indices. However, few literature articles have discussed the inferences for the difference in paired Youden indices. In this paper, we propose an exact confidence interval for the difference in paired Youden indices based on the generalized pivotal quantities. For comparison, the maximum likelihood estimate‐based interval and a bootstrap‐based interval are also included in the study for the difference in paired Youden indices. Abundant simulation studies are conducted to compare the relative performance of these intervals by evaluating the coverage probability and average interval length. Our simulation results demonstrate that the exact confidence interval outperforms the other two intervals even with small sample size when the underlying distributions are normal. A real application is also used to illustrate the proposed intervals. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
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995.
Bayesian model comparison for compartmental models with applications in positron emission tomography
We develop strategies for Bayesian modelling as well as model comparison, averaging and selection for compartmental models with particular emphasis on those that occur in the analysis of positron emission tomography (PET) data. Both modelling and computational issues are considered. Biophysically inspired informative priors are developed for the problem at hand, and by comparison with default vague priors it is shown that the proposed modelling is not overly sensitive to prior specification. It is also shown that an additive normal error structure does not describe measured PET data well, despite being very widely used, and that within a simple Bayesian framework simultaneous parameter estimation and model comparison can be performed with a more general noise model. The proposed approach is compared with standard techniques using both simulated and real data. In addition to good, robust estimation performance, the proposed technique provides, automatically, a characterisation of the uncertainty in the resulting estimates which can be considerable in applications such as PET. 相似文献
996.
功能性模型认为,提升警察信任的主要方法在于预防和控制犯罪,降低犯罪率与提升公众安全感;而表达性模型认为,提升警察信任更应注重维护社会正义与社区凝聚力。基于提出促进中国警察信任度提高的理论模型,提升公众获得感、幸福感、安全感,实现国家和社会整体安全的最终目的,采用结构方程模型验证“功能性-表达性模型”与中国警察信任关系的结果表明,功能性模型与表达性模型内部因素之间存在显著路径关系,同时功能性模型显著影响表达性模型指标进而改变公众对警察的信任程度。经调节效应分析后发现,主观社会阶层负向调节被害经历到犯罪恐惧感的直接路径,社交媒体使用负向调节犯罪恐惧感到警察信任的直接路径;在主观社会阶层和社交媒体使用的共同调节作用下,“被害经历→犯罪恐惧感→警察信任”中介路径效应值,随社交媒体使用频率的提升而增大,随主观社会阶层的升高而减小。 相似文献
997.
Although the concept of crisis severity has existed in the crisis communication literature for two decades, it has not been theoretically tested and explained. Based on Defensive Attribution Theory (DAT), this study intends to specify the relationship between crisis severity and crisis responsibility as well as organizational reputation within the SCCT model. Through a 2 (crisis severity) × 3 (crisis type) between-subject factorial experiment (n?=?274), the study revealed that higher crisis severity causes worse reputation regardless of crisis type. For accidental crisis, higher crisis severity leads to higher intentionality, one dimension of crisis responsibility. The findings indicate that crisis severity still has value in SCCT and deserves further investigation. 相似文献
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AbstractThis paper considers the optimization problems for a consecutive-2-out-of-n:G system where n is considered to be fixed or random. When the number of components is constant, the optimal number of components and the optimal replacement time are discussed by minimizing the expected cost rates. Furthermore, we focus on the above discussions again when n is a random variable. We give an approximate value of MTTF and propose the preventive replacement policy, respectively. 相似文献
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周舟 《成都大学学报(社会科学)》2015,(2):92-95
中国的教育体制正在迎来素质化改革,从高校教育到学龄前的儿童教育都面临着新的挑战和发展。儿童的创造力如何在繁重的学习压力下保持自身健康成长,对每一位教育工作者和家长来说都是一个重要的课题。文章结合动画这种大部分人从小都会接触的熟悉事物,尝试从动画的起源——定格动画中寻找到一些可行的方案,让儿童在动画充满想象力的奇特世界中通过动手来汲取更多的营养,放飞创造力的翅膀。 相似文献
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The case-cohort design is widely used as a means of reducing the cost in large cohort studies, especially when the disease rate is low and covariate measurements may be expensive, and has been discussed by many authors. In this paper, we discuss regression analysis of case-cohort studies that produce interval-censored failure time with dependent censoring, a situation for which there does not seem to exist an established approach. For inference, a sieve inverse probability weighting estimation procedure is developed with the use of Bernstein polynomials to approximate the unknown baseline cumulative hazard functions. The proposed estimators are shown to be consistent and the asymptotic normality of the resulting regression parameter estimators is established. A simulation study is conducted to assess the finite sample properties of the proposed approach and indicates that it works well in practical situations. The proposed method is applied to an HIV/AIDS case-cohort study that motivated this investigation. 相似文献