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51.
Current factory design and evaluation is very primitive. Factory components are designed in many cases independently. Product and process design are not well integrated. An encompassing framework is needed for iterating through a series of total factory designs, searching for optimal performance. In addition, a vehicle is needed for predicting the performance of a proposed advanced manufacturing system, so that engineers may have a sound means for evaluating such proposals. A heterarchical discrete manufacturing SIMNET II simulation model (SIMCELLS) was developed as a comprehensive methodology for designing and evaluating discrete manufacturing systems. SIMCELLS allows manufacturing systems engineers to experiment with alternative system structures and control strategies while seeking that combination of design features that will produce the desired overall system performance. The model in combination with a modernization programme is enabling a firm to successfully manufacture and sell trucks meeting international standards. The SIMNET II model  相似文献   
52.
The just-in-time (JIT) system has been studied extensively and implemented by a number of US firms as an ell'ective production system. The core of JIT involves determination of lot size and setup time reduction so as to increase manufacturing flexibility while minimizing the inventory level. This decision problem usually involves multiple conflicting objectives and mixed-model production. In this paper, goal programming (GP) is applied to a real-world JIT problem involving fabrication of different automotive and industrial rubber composite belts. The model results provide new insights concerning the conflicting nature of several goals, especially between meeting demand and reducing setup or idle time. Also, the GP solution is superior to the current JIT practice of the company.  相似文献   
53.
Abstract. Time‐to‐pregnancy (TTP) is the duration from the time a couple starts trying to become pregnant until they succeed. It is considered one of the most direct methods to measure natural fecundity in humans. Statistical tools for designing and analysing time to pregnancy studies belong to survival analysis, but several features require special attention. Prospective designs are difficult to carry out and retrospective (pregnancy‐based) designs, being widely used in this area, do not allow efficiently including couples remaining childless. A third possible design starts from a cross‐sectional sample of couples currently trying to become pregnant, using current duration (backward recurrence time) as basis for the estimation of TTP. Regression analysis is then most conveniently carried out in the accelerated failure time model. This paper surveys some practical and technical‐statistical issues in implementing this approach in a large telephone‐based survey, the Epidemiological Observatory of Fecundity in France (Obseff).  相似文献   
54.
This paper takes an initial step toward a better understanding of the complex set of pressing problems that need to be addressed by the Eastern European nonprofit sectors and their supporters in the near future. It gives an overview of the main challenges and claims that different nonprofit sectors of the region are at different crossroads. It identifies a general policy crisis that is fueled by the lack of a comprehensive knowledge of the sector and clear political intentions of cooperating with it. In addition, the dependence on foreign funding may result in a sustainability crisis in several Eastern European countries. In the most developed part of the region, the main elements of the present crisis are the fiscal, economic, effectiveness, identity, and legitimacy problems, which have something in common with the challenges facing the much more mature nonprofit sectors of the developed world.  相似文献   
55.
In this article, we investigate cosmopolitan attitudes among the people often considered the most cosmopolitan – the elite. Studying the typical class of frequent travellers provides a particularly good opportunity to study the relationship between transnational activities and cosmopolitanism. We also comprehensively investigate the link between postmaterialist values and cosmopolitan attitudes. We test our arguments using an original dataset that includes a relatively large sample of the German positional top elite in the years 2011 and 2012. A comparison between these data and data from a general population survey shows that while transnational activities affect the attitudes of ordinary citizens, increased travelling does not make elites more cosmopolitan. We discuss several reasons why this might be the case. We also observe that postmaterialist values and the ideological environment of the elite play a key role. Finally, we tentatively suggest that cosmopolitan elites do not endanger national social cohesion, as some fear they might. We show that cosmopolitanism and localism are not mutually exclusive and that members of the German elite feel even more attached to their nation than ordinary Germans.  相似文献   
56.
57.
The frequency of union dissolutions increased sharply over the past 40 years in Western Europe and North America, resulting in a rapid growth in the number of persons living with a second partner. In studies of the 1980s, primarily conducted within the context of marriage, second partnerships were generally found to be less stable than first unions, but more recent studies provide more conflicting evidence. Taking the example of France, we study whether the relationship between first and second union stability indeed reversed between the 1970s and the 2000s, and how union and individual characteristics contributed to changes over time. The analysis presented here is based on the French Generations and Gender Survey (2005). The article first provides an overview of the differences in marriage, childbearing and breakup behaviours in first and second unions. Second, a piecewise linear model for repeated events is used to compare women’s dissolution risks in first and second unions. The results show that over time, the higher instability of second compared to first unions disappeared. Further, women in second unions adopted unmarried cohabitation as a living arrangement more often across the whole period and were more likely to have stepchildren, which was associated with less stable unions. Taking into account this diversity of family situations, i.e. controlling for family form and children, second unions were more stable than first unions, even during the past. At both union orders, marriage breakup risks tended to stabilise despite a continuing increase in the prevalence of separation, which suggests that cohabitation increasingly acts as a filter for marriage.  相似文献   
58.
Shiftwork-induced sleep deprivation and circadian disruption probably leads to an increase in the production of cytokines and dysregulation of innate immune system, respectively. This project aims evaluating changes in salivary IL-1 beta, cortisol, and melatonin in night workers. Method. Two day and three night healthy workers participated in this study. Sleep was evaluated by actimetry and activity protocols. Saliva was collected at waking and bedtime the last workday and the following two days-off and was analyzed by ELISA. Results. Neither sleep duration nor efficiency showed any association with salivary IL-1beta. IL-1beta levels were higher at waking than at bedtime during working days for all workers, but only one day and one night-worker maintained this pattern and hormone rhythms during days off. For this night worker, melatonin levels were shifted to daytime. A second one presented clear alterations in IL-1beta and hormone rhythms on days-off. Conclusions. Our preliminary results suggest that night work can disturb the variation pattern of salivary IL-1beta. No association of this variation with sleep was observed. It seems that disruption in hormone rhythms interfere with salivary IL-1beta production. IL- 1beta production pattern seems to be maintained when rhythms are present, in spite of a shift in melatonin secretion.  相似文献   
59.
Through examining the hashtag #muslimcandyheartrejects, a one-time, short-term, joke hashtag used on Twitter among a group of Muslim tweeters in 2012, we argue that members of Muslim digital diaspora communities use social media to construct and reinforce a Muslim diaspora identity. The architecture of Twitter provides the structure for these engagements, while humor serves meaning-making, cohesion building, and tension-relief functions within the conversation. The conversation itself combines a variety of topics to both describe Muslim identity in diaspora and to critique both Muslim community practices and conditions for Muslims in non-Muslim countries.  相似文献   
60.
Urban Ecosystems - Wild bees provide pollination services and are currently declining at the global scale. A potential cause for this decline is competitive interactions with domestic honey bees....  相似文献   
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