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To address the risk posed to human health by the consumption of VTEC O157 within contaminated pork, lamb, and beef products within Great Britain, a quantitative risk assessment model has been developed. This model aims to simulate the prevalence and amount of VTEC O157 in different meat products at consumption within a single model framework by adapting previously developed models. The model is stochastic in nature, enabling both variability (natural variation between animals, carcasses, products) and uncertainty (lack of knowledge) about the input parameters to be modeled. Based on the model assumptions and data, it is concluded that the prevalence of VTEC O157 in meat products (joints and mince) at consumption is low (i.e., <0.04%). Beef products, particularly beef burgers, present the highest estimated risk with an estimated eight out of 100,000 servings on average resulting in human infection with VTEC O157.  相似文献   
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Poker-machine gamblers have been demonstrated to report increases in the urge to gamble following exposure to salient gambling cues. However, the processes which contribute to this urge to gamble remain to be understood. The present study aimed to investigate whether changes in the conscious experience of visual imagery, rationality and volitional control (over one’s thoughts, images and attention) predicted changes in the urge to gamble following exposure to a gambling cue. Thirty-one regular poker-machine gamblers who reported at least low levels of problem gambling on the Problem Gambling Severity Index (PGSI), were recruited to complete an online cue-reactivity experiment. Participants completed the PGSI, the visual imagery, rationality and volitional control subscales of the Phenomenology of Consciousness Inventory (PCI), and a visual analogue scale (VAS) assessing urge to gamble. Participants completed the PCI subscales and VAS at baseline, following a neutral video cue and following a gambling video cue. Urge to gamble was found to significantly increase from neutral cue to gambling cue (while controlling for baseline urge) and this increase was predicted by PGSI score. After accounting for the effects of problem-gambling severity, cue-reactive visual imagery, rationality and volitional control significantly improved the prediction of cue-reactive urge to gamble. The small sample size and limited participant characteristic data restricts the generalizability of the findings. Nevertheless, this is the first study to demonstrate that changes in the subjective experience of visual imagery, volitional control and rationality predict changes in the urge to gamble from neutral to gambling cue. The results suggest that visual imagery, rationality and volitional control may play an important role in the experience of the urge to gamble in poker-machine gamblers.  相似文献   
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This study describes home environmental features, safety issues, and health-related modifications in a community dwelling sample of 82 elderly people with dementia. Main barriers to the accessibility of the homes were steps both inside and outside the home. The majority of the caregivers had made home modifications that pertained mainly to physical limitations. Home modifications to support cognitive deficits were made to a lesser extent. The main barrier to the implementation of home modifications to accommodate the care recipient's memory loss was skepticism about their usefulness. Regarding the removal of physical barriers, financial constraints were most frequently mentioned.  相似文献   
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Instrumental support can foster or ameliorate parent experiences of work–family conflict. Based on theories relating social support to stress, a framework for considering how school support affects work–family conflict is proposed and tested. Parent experiences of instrumental support (school schedules, school service provision, and staff accessibility) and school demands on parents (volunteer and homework involvement) were investigated in relation to levels of work–family conflict. Work demands were related to both family-interference-with-work and work-interference-with family; family demands related only to time-based family-interference-with-work. Perceptions of school scheduling as supportive were related negatively to both time- and strain-based work-interference-with family, whereas perceptions of school transportation services were related to both time- and strain-based family-interference-with-work. No buffering effects of these types of support were found. Implications for how community organizations can play a role in ameliorating work–family conflict are discussed.  相似文献   
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The asymptotic results pertaining to the distribution of the log-likelihood ratio allow for the creation of a confidence region, which is a general extension of the confidence interval. Two- and three-dimensional regions can be displayed visually to describe the plausible region of the parameters of interest simultaneously. While most advanced statistical textbooks on inference discuss these asymptotic confidence regions, there is no exploration of how to numerically compute these regions for graphical purposes. This article demonstrates the application of a simple trigonometric transformation to compute two- and three-dimensional confidence regions; we transform the Cartesian coordinates of the parameters to create what we call the radial profile log-likelihood. The method is applicable to any distribution with a defined likelihood function, so it is not limited to specific data distributions or model paradigms. We describe the method along with the algorithm, follow with an example of our method, and end with an examination of computation time. Supplementary materials for this article are available online.  相似文献   
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